Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200330894> ?p ?o ?g. }
- W4200330894 endingPage "876" @default.
- W4200330894 startingPage "865" @default.
- W4200330894 abstract "Recently, a study showed that glycerol fermentation by Clostridium pasteurianum could be metabolically redirected when the electroactive bacterium Geobacter sulfurreducens was added in the culture. It was assumed that this metabolic shift of the fermentative species resulted from an interspecies electron transfer. The aim of this study was to find out the mechanisms used for this interaction and how they affect the metabolism of C. pasteurianum. To get insights into the mechanisms involved, several coculture setups and RNA sequencing with differential expression analysis were performed. As a result, a putative interaction model was proposed: G. sulfurreducens produces cobamide molecules that possibly modify C. pasteurianum metabolic pathway at the key enzyme glycerol dehydratase, and affect its vanadium nitrogenase expression. In addition, the results suggested that G. sulfurreducens' electrons could enter C. pasteurianum through its transmembrane flavin-bound polyferredoxin and cellular cytochrome b5-rubredoxin interplay, putatively reinforcing the metabolic shift. Unravelling the mechanisms behind the interaction between fermentative and electroactive bacteria helps to better understand the role of bacterial interactions in fermentation setups. KEY POINTS: • C. pasteurianum-G. sulfurreducens interaction inducing a metabolic shift is mediated • C. pasteurianum's metabolic shift in coculture might be induced by cobamides • Electrons possibly enter C. pasteurianum through a multiflavin polyferredoxin." @default.
- W4200330894 created "2021-12-31" @default.
- W4200330894 creator A5005393947 @default.
- W4200330894 creator A5012991850 @default.
- W4200330894 creator A5034244914 @default.
- W4200330894 creator A5040549205 @default.
- W4200330894 creator A5048625443 @default.
- W4200330894 creator A5073513056 @default.
- W4200330894 date "2021-12-23" @default.
- W4200330894 modified "2023-09-26" @default.
- W4200330894 title "Mechanisms underlying Clostridium pasteurianum’s metabolic shift when grown with Geobacter sulfurreducens" @default.
- W4200330894 cites W1532479482 @default.
- W4200330894 cites W1602874755 @default.
- W4200330894 cites W1625202529 @default.
- W4200330894 cites W1640038695 @default.
- W4200330894 cites W1828900086 @default.
- W4200330894 cites W1991550311 @default.
- W4200330894 cites W2003246897 @default.
- W4200330894 cites W2006610149 @default.
- W4200330894 cites W2021341670 @default.
- W4200330894 cites W2036167123 @default.
- W4200330894 cites W2056535655 @default.
- W4200330894 cites W2074316065 @default.
- W4200330894 cites W2079709777 @default.
- W4200330894 cites W2086677226 @default.
- W4200330894 cites W2103017472 @default.
- W4200330894 cites W2103441770 @default.
- W4200330894 cites W2108234281 @default.
- W4200330894 cites W2120024428 @default.
- W4200330894 cites W2124799197 @default.
- W4200330894 cites W2129753011 @default.
- W4200330894 cites W2138207763 @default.
- W4200330894 cites W2156333289 @default.
- W4200330894 cites W2159431397 @default.
- W4200330894 cites W2164154943 @default.
- W4200330894 cites W2179438025 @default.
- W4200330894 cites W2328448938 @default.
- W4200330894 cites W2393928818 @default.
- W4200330894 cites W2408404713 @default.
- W4200330894 cites W2548455443 @default.
- W4200330894 cites W2582378544 @default.
- W4200330894 cites W2596823135 @default.
- W4200330894 cites W2606463463 @default.
- W4200330894 cites W2618064434 @default.
- W4200330894 cites W2734360091 @default.
- W4200330894 cites W2745163464 @default.
- W4200330894 cites W2755336277 @default.
- W4200330894 cites W2790050048 @default.
- W4200330894 cites W2840480151 @default.
- W4200330894 cites W2890807726 @default.
- W4200330894 cites W2919392282 @default.
- W4200330894 cites W2950221693 @default.
- W4200330894 cites W2981480910 @default.
- W4200330894 cites W2982602599 @default.
- W4200330894 cites W2991299717 @default.
- W4200330894 cites W3008096504 @default.
- W4200330894 cites W3038922381 @default.
- W4200330894 cites W3042561839 @default.
- W4200330894 cites W3094967361 @default.
- W4200330894 cites W3107978144 @default.
- W4200330894 cites W3110435477 @default.
- W4200330894 cites W3128643980 @default.
- W4200330894 cites W4643690 @default.
- W4200330894 doi "https://doi.org/10.1007/s00253-021-11736-7" @default.
- W4200330894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34939136" @default.
- W4200330894 hasPublicationYear "2021" @default.
- W4200330894 type Work @default.
- W4200330894 citedByCount "2" @default.
- W4200330894 countsByYear W42003308942022 @default.
- W4200330894 countsByYear W42003308942023 @default.
- W4200330894 crossrefType "journal-article" @default.
- W4200330894 hasAuthorship W4200330894A5005393947 @default.
- W4200330894 hasAuthorship W4200330894A5012991850 @default.
- W4200330894 hasAuthorship W4200330894A5034244914 @default.
- W4200330894 hasAuthorship W4200330894A5040549205 @default.
- W4200330894 hasAuthorship W4200330894A5048625443 @default.
- W4200330894 hasAuthorship W4200330894A5073513056 @default.
- W4200330894 hasBestOaLocation W42003308942 @default.
- W4200330894 hasConcept C12554922 @default.
- W4200330894 hasConcept C134621786 @default.
- W4200330894 hasConcept C181199279 @default.
- W4200330894 hasConcept C185592680 @default.
- W4200330894 hasConcept C192989942 @default.
- W4200330894 hasConcept C2779812452 @default.
- W4200330894 hasConcept C2781092032 @default.
- W4200330894 hasConcept C2900893 @default.
- W4200330894 hasConcept C523546767 @default.
- W4200330894 hasConcept C54355233 @default.
- W4200330894 hasConcept C55493867 @default.
- W4200330894 hasConcept C58123911 @default.
- W4200330894 hasConcept C62231903 @default.
- W4200330894 hasConcept C86803240 @default.
- W4200330894 hasConcept C95444343 @default.
- W4200330894 hasConceptScore W4200330894C12554922 @default.
- W4200330894 hasConceptScore W4200330894C134621786 @default.
- W4200330894 hasConceptScore W4200330894C181199279 @default.
- W4200330894 hasConceptScore W4200330894C185592680 @default.
- W4200330894 hasConceptScore W4200330894C192989942 @default.