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- W4200345586 abstract "Two undescribed phenolic derivatives musaones A and B, six undescribed γ-butyrolactone musaolides A-F, together with two undescribed cyclopentanone musaolides G and H were isolated from the solid culture of an endophytic strain Phaeosphaeriopsis musae M. Arzanlou & Crous (Phaeosphaeriaceae). Their structures were unambiguously elucidated by extensive spectral analyses. The absolute configurations of two diastereomers musaolides G and H were assigned by comparing their experimental and calculated ECD data. Moreover, the in vitro α-glucosidase inhibition and cytotoxic activities of isolated compounds (except musaolide D) were evaluated to understand their biological effects, wherein musaone B and musaolide F displayed promising α-glucosidase inhibition with IC50 values of 37.3 ± 0.59 μM and 105.18 ± 2.76 μM respectively, compared to the positive control acarbose (24.99 ± 1.28 μM)." @default.
- W4200345586 created "2021-12-31" @default.
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- W4200345586 date "2022-03-01" @default.
- W4200345586 modified "2023-09-23" @default.
- W4200345586 title "Bioactive polyketide derivatives from the endophytic fungus Phaeosphaeriopsis musa" @default.
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- W4200345586 doi "https://doi.org/10.1016/j.phytochem.2021.113055" @default.
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