FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200346650> ?p ?o ?g. }

• W4200346650 endingPage "354" @default.
• W4200346650 startingPage "343" @default.
• W4200346650 abstract "Exosomes are membrane bound extracellular vesicles that play an important role in many biological processes. While they have great application value, exosome isolation is still considered a major scientific challenge. In the present study, a novel separation strategy for exosomes is proposed based on the specific interaction between immobilized peptide ligands and phosphatidylserine moieties which are highly abundant on the surface of exosomes. With the new affinity method, intact model exosomes can be recovered with a high yield in a short processing time. The purity of exosome samples enriched from serum by the affinity method is far higher than that isolated by ultrafiltration, and similar to that obtained by density gradient centrifugation and ultracentrifugation. Moreover, the variety of contaminants co-isolated by the affinity method is relatively low due to its specific separation principle. Proteomics analysis of exosomes isolated by the affinity method from the serum of healthy, hepatocellular carcinoma patients, and intrahepatic cholangiocarcinoma patients was performed to prove the applicability of this method. In conclusion, our novel strategy shows characteristics of easy preparation, high specificity, and cost-effectiveness, and provides a promising approach for exosome isolation which should have wide applications." @default.
• W4200346650 created "2021-12-31" @default.
• W4200346650 creator A5003642180 @default.
• W4200346650 creator A5006313457 @default.
• W4200346650 creator A5010607811 @default.
• W4200346650 creator A5017950267 @default.
• W4200346650 creator A5025615349 @default.
• W4200346650 creator A5026785307 @default.
• W4200346650 creator A5038858339 @default.
• W4200346650 creator A5079139980 @default.
• W4200346650 date "2022-09-01" @default.
• W4200346650 modified "2023-10-17" @default.
• W4200346650 title "Peptide ligand-SiO2 microspheres with specific affinity for phosphatidylserine as a new strategy to isolate exosomes and application in proteomics to differentiate hepatic cancer" @default.
• W4200346650 cites W1794677843 @default.
• W4200346650 cites W2006332321 @default.
• W4200346650 cites W2009628603 @default.
• W4200346650 cites W2024720397 @default.
• W4200346650 cites W2061996203 @default.
• W4200346650 cites W2072167135 @default.
• W4200346650 cites W2082439103 @default.
• W4200346650 cites W2086268589 @default.
• W4200346650 cites W2091868933 @default.
• W4200346650 cites W2112391486 @default.
• W4200346650 cites W2123614057 @default.
• W4200346650 cites W2137245183 @default.
• W4200346650 cites W2166027129 @default.
• W4200346650 cites W2414083225 @default.
• W4200346650 cites W2522821491 @default.
• W4200346650 cites W2553886049 @default.
• W4200346650 cites W2582091628 @default.
• W4200346650 cites W2600094664 @default.
• W4200346650 cites W2607237735 @default.
• W4200346650 cites W2607716704 @default.
• W4200346650 cites W2619076775 @default.
• W4200346650 cites W2640213649 @default.
• W4200346650 cites W2738491178 @default.
• W4200346650 cites W2751681739 @default.
• W4200346650 cites W2753937241 @default.
• W4200346650 cites W2772391116 @default.
• W4200346650 cites W2783798137 @default.
• W4200346650 cites W2789596991 @default.
• W4200346650 cites W2797361394 @default.
• W4200346650 cites W2800337771 @default.
• W4200346650 cites W2801124446 @default.
• W4200346650 cites W2884761045 @default.
• W4200346650 cites W2890807645 @default.
• W4200346650 cites W2895641553 @default.
• W4200346650 cites W2896616277 @default.
• W4200346650 cites W2897629267 @default.
• W4200346650 cites W2903530962 @default.
• W4200346650 cites W2925579059 @default.
• W4200346650 cites W2944848693 @default.
• W4200346650 cites W2972920912 @default.
• W4200346650 cites W2980151372 @default.
• W4200346650 cites W2990529806 @default.
• W4200346650 cites W2992570326 @default.
• W4200346650 cites W3005104290 @default.
• W4200346650 cites W3048596299 @default.
• W4200346650 cites W3084205805 @default.
• W4200346650 cites W4211008300 @default.
• W4200346650 doi "https://doi.org/10.1016/j.bioactmat.2021.12.017" @default.
• W4200346650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35356814" @default.
• W4200346650 hasPublicationYear "2022" @default.
• W4200346650 type Work @default.
• W4200346650 citedByCount "11" @default.
• W4200346650 countsByYear W42003466502022 @default.
• W4200346650 countsByYear W42003466502023 @default.
• W4200346650 crossrefType "journal-article" @default.
• W4200346650 hasAuthorship W4200346650A5003642180 @default.
• W4200346650 hasAuthorship W4200346650A5006313457 @default.
• W4200346650 hasAuthorship W4200346650A5010607811 @default.
• W4200346650 hasAuthorship W4200346650A5017950267 @default.
• W4200346650 hasAuthorship W4200346650A5025615349 @default.
• W4200346650 hasAuthorship W4200346650A5026785307 @default.
• W4200346650 hasAuthorship W4200346650A5038858339 @default.
• W4200346650 hasAuthorship W4200346650A5079139980 @default.
• W4200346650 hasBestOaLocation W42003466501 @default.
• W4200346650 hasConcept C104317684 @default.
• W4200346650 hasConcept C132946820 @default.
• W4200346650 hasConcept C145059251 @default.
• W4200346650 hasConcept C179247698 @default.
• W4200346650 hasConcept C181199279 @default.
• W4200346650 hasConcept C185592680 @default.
• W4200346650 hasConcept C20518536 @default.
• W4200346650 hasConcept C2778918659 @default.
• W4200346650 hasConcept C2779281246 @default.
• W4200346650 hasConcept C2779637612 @default.
• W4200346650 hasConcept C2781261824 @default.
• W4200346650 hasConcept C41625074 @default.
• W4200346650 hasConcept C43617362 @default.
• W4200346650 hasConcept C46111723 @default.
• W4200346650 hasConcept C54689828 @default.
• W4200346650 hasConcept C55493867 @default.
• W4200346650 hasConceptScore W4200346650C104317684 @default.
• W4200346650 hasConceptScore W4200346650C132946820 @default.
• W4200346650 hasConceptScore W4200346650C145059251 @default.
• W4200346650 hasConceptScore W4200346650C179247698 @default.
• W4200346650 hasConceptScore W4200346650C181199279 @default.

• next