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- W4200360862 abstract "Cardiovascular disease accounts for more than 17 million deaths globally every year, of which complications of hypertension account for 9.4 million deaths worldwide. Early detection and management of hypertension can prevent costly interventions, including dialysis and cardiac surgery. Non-pharmacological approaches for managing hypertension commonly involve lifestyle modification, including exercise and dietary regulations such as reducing salt and fluid intake; however, a majority of patients will eventually require antihypertensive medications. In 2020, the International Society of Hypertension published worldwide guidelines in its efforts to reduce the global prevalence of raised blood pressure (BP) in adults aged 18 years or over. Currently, several classes of medications are used to control hypertension, either as mono- or combination therapy depending on the disease severity. These drug classes include those that target the renin-angiotensin-aldosterone system (RAAS) and adrenergic receptors, calcium channel blockers, diuretics and vasodilators. While some of these classes of medications have shown significant benefits in controlling BP and reducing cardiovascular mortality, the prevalence of hypertension remains high. Significant efforts have been made in developing new classes of drugs that lower BP; these medications exert their therapeutic benefits through different pathways and mechanism of actions. With several of these emerging classes in phase III clinical trials, it is hoped that the discovery of these novel therapeutic avenues will aid in reducing the global burden of hypertension." @default.
- W4200360862 created "2021-12-31" @default.
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- W4200360862 date "2021-12-08" @default.
- W4200360862 modified "2023-10-06" @default.
- W4200360862 title "Current and Emerging Classes of Pharmacological Agents for the Management of Hypertension" @default.
- W4200360862 cites W1495136860 @default.
- W4200360862 cites W1508421392 @default.
- W4200360862 cites W1555341178 @default.
- W4200360862 cites W1577634658 @default.
- W4200360862 cites W1753850950 @default.
- W4200360862 cites W1811184201 @default.
- W4200360862 cites W1821239563 @default.
- W4200360862 cites W1886334003 @default.
- W4200360862 cites W1930564149 @default.
- W4200360862 cites W1937226585 @default.
- W4200360862 cites W1969072445 @default.
- W4200360862 cites W1977607782 @default.
- W4200360862 cites W1977711279 @default.
- W4200360862 cites W1978012152 @default.
- W4200360862 cites W1978517521 @default.
- W4200360862 cites W1980766884 @default.
- W4200360862 cites W1986122868 @default.
- W4200360862 cites W1988918323 @default.
- W4200360862 cites W1991393575 @default.
- W4200360862 cites W1998146750 @default.
- W4200360862 cites W2004775683 @default.
- W4200360862 cites W2008045175 @default.
- W4200360862 cites W2012591190 @default.
- W4200360862 cites W2013354239 @default.
- W4200360862 cites W2017831416 @default.
- W4200360862 cites W2020498330 @default.
- W4200360862 cites W202512764 @default.
- W4200360862 cites W2030435316 @default.
- W4200360862 cites W2032473880 @default.
- W4200360862 cites W2032678337 @default.
- W4200360862 cites W2040842213 @default.
- W4200360862 cites W2048114546 @default.
- W4200360862 cites W2062126244 @default.
- W4200360862 cites W2062187031 @default.
- W4200360862 cites W2064433742 @default.
- W4200360862 cites W2068759718 @default.
- W4200360862 cites W2073417228 @default.
- W4200360862 cites W2073756362 @default.
- W4200360862 cites W2074921868 @default.
- W4200360862 cites W2077038286 @default.
- W4200360862 cites W2079883736 @default.
- W4200360862 cites W2081374800 @default.
- W4200360862 cites W2081597080 @default.
- W4200360862 cites W2084191761 @default.
- W4200360862 cites W2096431191 @default.
- W4200360862 cites W2104458786 @default.
- W4200360862 cites W2105551553 @default.
- W4200360862 cites W2110051876 @default.
- W4200360862 cites W2113972884 @default.
- W4200360862 cites W2114369401 @default.
- W4200360862 cites W2118113989 @default.
- W4200360862 cites W2119369921 @default.
- W4200360862 cites W2121759271 @default.
- W4200360862 cites W2126125759 @default.
- W4200360862 cites W2129832544 @default.
- W4200360862 cites W2129991662 @default.
- W4200360862 cites W2133217116 @default.
- W4200360862 cites W2134726862 @default.
- W4200360862 cites W2135521686 @default.
- W4200360862 cites W2139561039 @default.
- W4200360862 cites W2143954917 @default.
- W4200360862 cites W2146764370 @default.
- W4200360862 cites W21478844 @default.
- W4200360862 cites W2150392479 @default.
- W4200360862 cites W2150599338 @default.
- W4200360862 cites W2151003504 @default.
- W4200360862 cites W2153299838 @default.
- W4200360862 cites W2161358815 @default.
- W4200360862 cites W2162304120 @default.
- W4200360862 cites W2164227528 @default.
- W4200360862 cites W2165472412 @default.
- W4200360862 cites W2166819422 @default.
- W4200360862 cites W2171146813 @default.
- W4200360862 cites W2172025889 @default.
- W4200360862 cites W2172032309 @default.
- W4200360862 cites W2306940576 @default.
- W4200360862 cites W2324112105 @default.
- W4200360862 cites W2342465070 @default.
- W4200360862 cites W2475261460 @default.
- W4200360862 cites W2521000591 @default.
- W4200360862 cites W2562329777 @default.
- W4200360862 cites W2562411701 @default.
- W4200360862 cites W2591873133 @default.
- W4200360862 cites W2606476580 @default.
- W4200360862 cites W2607031541 @default.