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- W4200361567 abstract "Patients with end-stage heart failure often present with concomitant end-stage renal or end-stage liver disease requiring transplantation. There are limited data regarding the risks, benefits and long-term outcomes of heart-kidney (HKT) and heart-liver transplantation (HLT), and guidelines are mainly limited to expert consensus statements.The incidence of HKT and HLT has steadily increased in recent years with favourable outcomes. Both single-centre and large database studies have shown benefits of HKT/HLT through improved survival, freedom from dialysis and lower rates of rejection and coronary allograft vasculopathy. Current guidelines are institution dependent and controversial due to the ethical considerations surrounding multiorgan transplantation (MOT).MOT is an effective and necessary option for patients with end-stage heart and kidney/liver failure. MOT is ethically permissible, and efforts should be made to consider eligible patients as early as possible to limit morbidity and mortality. Further research is needed regarding appropriate listing criteria and long-term outcomes." @default.
- W4200361567 created "2021-12-31" @default.
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- W4200361567 date "2021-12-09" @default.
- W4200361567 modified "2023-09-26" @default.
- W4200361567 title "Two is better than one: when to consider multiorgan transplant" @default.
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- W4200361567 doi "https://doi.org/10.1097/mot.0000000000000951" @default.
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