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- W4200363460 abstract "To determine if childhood obesity has an effect on the ocular surface and tear film of children who are afflicted.Patients who had childhood obesity, 85 eyes, and patients who were healthy, 75 eyes, were enrolled in this prospective and comparative study. The tear film breakup time (TF-BUT), tear meniscus area and height (TMA and TMH) values, Schirmer test scores, and ocular surface disease index (OSDI) scores were obtained for all participants.The TMH, TMA, TF-BUT, and Schirmer test results were statistically significantly lower in the obesity group (p < 0.001 for all). The children with obesity and insulin resistance had lower TMH, TMA, TF-BUT, and Schirmer test results when compared to the children without insulin resistance (p < 0.05 for all). The body mass index was found to be correlated with the TMH, TMA, TF-BUT, and Schirmer test results (p < 0.001 for all).Children with obesity had lower TMA, TMH, TF-BUT, and Schirmer test results than healthy subjects. When insulin resistance was added to obesity, these values were even lower.Untersuchungen zum Zusammenhang zwischen Fettleibigkeit bei Kindern und dem Tränenfilm betroffener Kinder.Von Patienten mit Adipositas im Kindesalter wurden 85 Augen und von gesunden Patienten 75 Augen in diese prospektive und vergleichende Designstudie eingeschlossen. Für alle Teilnehmer wurden die Werte für die Tränenfilmauflösungszeit (TF-BUT), die Tränenmeniskusfläche und -höhe (TMA und TMH), die Schirmer-Testwerte und die OSDI-Werte (OSDI: Ocular Surface Disease Index) ermittelt.Die TMH-, TMA-, TF-BUT- und Schirmer-Testergebnisse waren in der Adipositasgruppe statistisch signifikant niedriger (p < 0,001 für alle). Die Kinder mit Fettleibigkeit und Insulinresistenz hatten niedrigere TMH-, TMA-, TF-BUT- und Schirmer-Testergebnisse im Vergleich zu den Kindern ohne Insulinresistenz (p < 0,05 für alle). Es wurde festgestellt, dass der Body-Mass-Index mit den TMH-, TMA-, TF-BUT- und Schirmer-Testergebnissen korreliert (p < 0,001 für alle).Die Kinder mit Adipositas hatten niedrigere TMA-, TMH-, TF-BUT- und Schirmer-Testergebnisse als gesunde Probanden. Wenn die Insulinresistenz zu Fettleibigkeit hinzugefügt wurde, waren diese Werte noch niedriger." @default.
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- W4200363460 date "2021-12-15" @default.
- W4200363460 modified "2023-10-18" @default.
- W4200363460 title "Assessment of Tear Film Anomalies in Childhood Obesity" @default.
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- W4200363460 doi "https://doi.org/10.1055/a-1668-0276" @default.
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