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- W4200367885 abstract "The most effective method to mitigate decompression sickness in divers is hyperbaric oxygen (HBO2) pre-breathing. However, divers breathing HBO2 are at risk for developing central nervous system oxygen toxicity (CNS-OT), which can manifest as symptoms that might impair a diver's performance, or cause more serious symptoms like seizures. In this study, we have collected electrodermal activity (EDA) signals in fifteen subjects at elevated oxygen partial pressures (2.06 ATA, 35 FSW) in the foxtrot chamber pool at the Duke University Hyperbaric Center, while performing a cognitive stress test for up to 120 minutes. Specifically, we have computed the time-varying spectral analysis of EDA (TVSymp) as a tool for sympathetic tone assessment and evaluated its feasibility for the prediction of symptoms of CNS-OT in divers. The preliminary results show large increase in the amplitude TVSymp values derived from EDA recordings ~2 minutes prior to expert human adjudication of symptoms related to oxygen toxicity. An early detection based on TVSymp might allow the diver to take countermeasures against the dire consequences of CNS-OT which can lead to drowning.Clinical Relevance-This study provides a sensitive analysis method which indicates a significant increase in the electrodermal activity prior to human expert adjudication of symptoms related to CNS-OT." @default.
- W4200367885 created "2021-12-31" @default.
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- W4200367885 date "2021-11-01" @default.
- W4200367885 modified "2023-09-27" @default.
- W4200367885 title "Time-varying Spectral Index of Electrodermal Activity to Predict Central Nervous System Oxygen Toxicity Symptoms in Divers: Preliminary results" @default.
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- W4200367885 doi "https://doi.org/10.1109/embc46164.2021.9629924" @default.
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