FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200368905> ?p ?o ?g. }

• W4200368905 endingPage "504" @default.
• W4200368905 startingPage "493" @default.
• W4200368905 abstract "Haemophagocytic lymphohistiocytosis (HLH) is a rare hyper-inflammatory condition with poor outcomes.Few population-based estimates of the incidence and survival in adults exist. We aimed to provide these data for England.We used population-based linked data from primary care, secondary care, cancer registries and mortality databases in England to identify people diagnosed with HLH between 1 January 2000 and 31 December 2016. We calculated annual incidence rates by age and sex, modelled change in incidence over time with Poisson regression, calculated overall 1-year survival using Kaplan-Meier methods and estimated adjusted hazard ratios (HRs) of death using a Cox proportional hazards model.We identified 214 patients with HLH. The reported age and sex-adjusted incidence increased twofold over the period, from around one to around two per million. Incidence was highest in those below 1 year (14.6 per million) and ≥75 years (2.2 per million), and lowest in those aged 15-44 years (0.8 per million). One-year survival varied by age and sex from 77% (95% confidence interval [CI] 63%-86%) in those <15 years to 30% (95% CI 14%-49%) in those ≥75. In patients with haematological cancer, the adjusted HR for death was 2.60 (95% CI 1.45-4.66) compared to patients with no malignant or rheumatological disease.The incidence of HLH diagnosis in England has increased between 2000 and 2016 and occurs in all ages with varying underlying diseases. One-year survival varies substantially, being particularly poor in those aged over 75 years and those with haematological malignancy." @default.
• W4200368905 created "2021-12-31" @default.
• W4200368905 creator A5014238582 @default.
• W4200368905 creator A5017095589 @default.
• W4200368905 creator A5025808265 @default.
• W4200368905 creator A5029918292 @default.
• W4200368905 creator A5031678815 @default.
• W4200368905 creator A5051153337 @default.
• W4200368905 creator A5061036825 @default.
• W4200368905 creator A5063224846 @default.
• W4200368905 creator A5074552203 @default.
• W4200368905 creator A5083217353 @default.
• W4200368905 creator A5086477783 @default.
• W4200368905 creator A5086557429 @default.
• W4200368905 date "2021-12-22" @default.
• W4200368905 modified "2023-09-27" @default.
• W4200368905 title "Incidence and survival of haemophagocytic lymphohistiocytosis: A population‐based cohort study from England" @default.
• W4200368905 cites W1505641753 @default.
• W4200368905 cites W1530342027 @default.
• W4200368905 cites W1652620147 @default.
• W4200368905 cites W2001492097 @default.
• W4200368905 cites W2043530968 @default.
• W4200368905 cites W2061534249 @default.
• W4200368905 cites W2066746871 @default.
• W4200368905 cites W2069381373 @default.
• W4200368905 cites W2102180920 @default.
• W4200368905 cites W2146417320 @default.
• W4200368905 cites W2162251899 @default.
• W4200368905 cites W2163067702 @default.
• W4200368905 cites W2170319894 @default.
• W4200368905 cites W2171678723 @default.
• W4200368905 cites W2295521935 @default.
• W4200368905 cites W2345859514 @default.
• W4200368905 cites W2417246715 @default.
• W4200368905 cites W2499603116 @default.
• W4200368905 cites W2607418663 @default.
• W4200368905 cites W2608320814 @default.
• W4200368905 cites W2625802019 @default.
• W4200368905 cites W2755192480 @default.
• W4200368905 cites W2790210283 @default.
• W4200368905 cites W2793254732 @default.
• W4200368905 cites W2887068202 @default.
• W4200368905 cites W2889907608 @default.
• W4200368905 cites W2936019126 @default.
• W4200368905 cites W2940683302 @default.
• W4200368905 cites W2970701054 @default.
• W4200368905 cites W2998160446 @default.
• W4200368905 cites W3008297186 @default.
• W4200368905 cites W3023366480 @default.
• W4200368905 cites W3034960314 @default.
• W4200368905 cites W3106284751 @default.
• W4200368905 cites W3108411523 @default.
• W4200368905 cites W3112209524 @default.
• W4200368905 cites W3149026346 @default.
• W4200368905 cites W3161544585 @default.
• W4200368905 doi "https://doi.org/10.1111/joim.13432" @default.
• W4200368905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34875131" @default.
• W4200368905 hasPublicationYear "2021" @default.
• W4200368905 type Work @default.
• W4200368905 citedByCount "8" @default.
• W4200368905 countsByYear W42003689052022 @default.
• W4200368905 countsByYear W42003689052023 @default.
• W4200368905 crossrefType "journal-article" @default.
• W4200368905 hasAuthorship W4200368905A5014238582 @default.
• W4200368905 hasAuthorship W4200368905A5017095589 @default.
• W4200368905 hasAuthorship W4200368905A5025808265 @default.
• W4200368905 hasAuthorship W4200368905A5029918292 @default.
• W4200368905 hasAuthorship W4200368905A5031678815 @default.
• W4200368905 hasAuthorship W4200368905A5051153337 @default.
• W4200368905 hasAuthorship W4200368905A5061036825 @default.
• W4200368905 hasAuthorship W4200368905A5063224846 @default.
• W4200368905 hasAuthorship W4200368905A5074552203 @default.
• W4200368905 hasAuthorship W4200368905A5083217353 @default.
• W4200368905 hasAuthorship W4200368905A5086477783 @default.
• W4200368905 hasAuthorship W4200368905A5086557429 @default.
• W4200368905 hasBestOaLocation W42003689052 @default.
• W4200368905 hasConcept C10515644 @default.
• W4200368905 hasConcept C107130276 @default.
• W4200368905 hasConcept C120665830 @default.
• W4200368905 hasConcept C121332964 @default.
• W4200368905 hasConcept C126322002 @default.
• W4200368905 hasConcept C144024400 @default.
• W4200368905 hasConcept C149923435 @default.
• W4200368905 hasConcept C187212893 @default.
• W4200368905 hasConcept C207103383 @default.
• W4200368905 hasConcept C2908647359 @default.
• W4200368905 hasConcept C44249647 @default.
• W4200368905 hasConcept C50382708 @default.
• W4200368905 hasConcept C61511704 @default.
• W4200368905 hasConcept C71924100 @default.
• W4200368905 hasConcept C72563966 @default.
• W4200368905 hasConcept C73269764 @default.
• W4200368905 hasConcept C99454951 @default.
• W4200368905 hasConceptScore W4200368905C10515644 @default.
• W4200368905 hasConceptScore W4200368905C107130276 @default.
• W4200368905 hasConceptScore W4200368905C120665830 @default.
• W4200368905 hasConceptScore W4200368905C121332964 @default.
• W4200368905 hasConceptScore W4200368905C126322002 @default.

• next