FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200375989> ?p ?o ?g. }

• W4200375989 endingPage "1345" @default.
• W4200375989 startingPage "1345" @default.
• W4200375989 abstract "Approximately 40% of patients with diffuse large B cell lymphoma (DLBCL) do not respond or develop relapsed disease after first-line chemoimmunotherapy. A minority of these patients can be cured with autologous hematopoietic stem cell transplantation (AHCT). Although chimeric antigen receptor (CAR) T cells have transformed the treatment paradigm of relapsed/refractory DLBCL, only 30-40% of patients achieve durable remissions. In addition, many patients with relapsed/refractory DLBCL are ineligible to receive treatment with CAR T cells due to comorbidities or logistical limitations. Since 2019, the following four non-CAR T-cell treatments have been approved in relapsed/refractory DLBCL: polatuzumab in combination with bendamustine and rituximab, selinexor, tafasitamab plus lenalidomide, and loncastuximab. In this article, I review the data behind these four approvals and discuss important considerations on their use in clinical practice. I also review emerging therapies that have shown promising early results in relapsed/refractory DLBCL including the bispecific antibodies, antibody-drug conjugates, Bruton tyrosine kinase inhibitors, BCL2 inhibitors, immune checkpoint inhibitors, and epigenetic modifiers." @default.
• W4200375989 created "2021-12-31" @default.
• W4200375989 creator A5017559837 @default.
• W4200375989 date "2021-12-10" @default.
• W4200375989 modified "2023-10-16" @default.
• W4200375989 title "Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Look at the Approved and Emerging Therapies" @default.
• W4200375989 cites W1020989877 @default.
• W4200375989 cites W1973628185 @default.
• W4200375989 cites W1997353354 @default.
• W4200375989 cites W2018071905 @default.
• W4200375989 cites W2024373518 @default.
• W4200375989 cites W2026374501 @default.
• W4200375989 cites W2044352858 @default.
• W4200375989 cites W2046816028 @default.
• W4200375989 cites W2055352702 @default.
• W4200375989 cites W2055773216 @default.
• W4200375989 cites W2103746815 @default.
• W4200375989 cites W2109440389 @default.
• W4200375989 cites W2117460825 @default.
• W4200375989 cites W2120775216 @default.
• W4200375989 cites W2126772526 @default.
• W4200375989 cites W2127018518 @default.
• W4200375989 cites W2141920998 @default.
• W4200375989 cites W2145785161 @default.
• W4200375989 cites W2146651952 @default.
• W4200375989 cites W2147246240 @default.
• W4200375989 cites W2150129319 @default.
• W4200375989 cites W2150587745 @default.
• W4200375989 cites W2153558008 @default.
• W4200375989 cites W2158267770 @default.
• W4200375989 cites W2237058775 @default.
• W4200375989 cites W2279127916 @default.
• W4200375989 cites W2280483683 @default.
• W4200375989 cites W2300442403 @default.
• W4200375989 cites W2484616545 @default.
• W4200375989 cites W2518731208 @default.
• W4200375989 cites W2557253070 @default.
• W4200375989 cites W2580493818 @default.
• W4200375989 cites W2582696216 @default.
• W4200375989 cites W2605009867 @default.
• W4200375989 cites W2607299002 @default.
• W4200375989 cites W2609884290 @default.
• W4200375989 cites W2624307079 @default.
• W4200375989 cites W2744261860 @default.
• W4200375989 cites W2773804840 @default.
• W4200375989 cites W2789949637 @default.
• W4200375989 cites W2790566984 @default.
• W4200375989 cites W2790840176 @default.
• W4200375989 cites W2792232222 @default.
• W4200375989 cites W2802559042 @default.
• W4200375989 cites W2899044337 @default.
• W4200375989 cites W2903062212 @default.
• W4200375989 cites W2903225254 @default.
• W4200375989 cites W2904110283 @default.
• W4200375989 cites W2907944761 @default.
• W4200375989 cites W2909334052 @default.
• W4200375989 cites W2918959628 @default.
• W4200375989 cites W2934686121 @default.
• W4200375989 cites W2962711446 @default.
• W4200375989 cites W2969216121 @default.
• W4200375989 cites W2973850435 @default.
• W4200375989 cites W2983242185 @default.
• W4200375989 cites W2983366686 @default.
• W4200375989 cites W2984927918 @default.
• W4200375989 cites W2986196170 @default.
• W4200375989 cites W2991516079 @default.
• W4200375989 cites W2998129775 @default.
• W4200375989 cites W3001767756 @default.
• W4200375989 cites W3013817962 @default.
• W4200375989 cites W3014583893 @default.
• W4200375989 cites W3026000147 @default.
• W4200375989 cites W3027036348 @default.
• W4200375989 cites W3034162969 @default.
• W4200375989 cites W3037697670 @default.
• W4200375989 cites W3048990846 @default.
• W4200375989 cites W3082855561 @default.
• W4200375989 cites W3089094196 @default.
• W4200375989 cites W3094712772 @default.
• W4200375989 cites W3094763563 @default.
• W4200375989 cites W3095664938 @default.
• W4200375989 cites W3095704533 @default.
• W4200375989 cites W3095832065 @default.
• W4200375989 cites W3096107020 @default.
• W4200375989 cites W3096548119 @default.
• W4200375989 cites W3111329327 @default.
• W4200375989 cites W3132778321 @default.
• W4200375989 cites W3137447968 @default.
• W4200375989 cites W3161133732 @default.
• W4200375989 cites W3176363517 @default.
• W4200375989 cites W3177222765 @default.
• W4200375989 cites W3180046707 @default.
• W4200375989 cites W3180238237 @default.
• W4200375989 cites W3198713553 @default.
• W4200375989 cites W3203991390 @default.
• W4200375989 cites W4200570830 @default.
• W4200375989 cites W4246296409 @default.
• W4200375989 doi "https://doi.org/10.3390/jpm11121345" @default.
• W4200375989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34945817" @default.

• next