Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200379904> ?p ?o ?g. }
- W4200379904 abstract "The difficulty of faithfully recapitulating malarial protein complexes in heterologous expression systems has long impeded structural study for much of the Plasmodium falciparum proteome. However, recent advances in single-particle cryo electron microscopy (cryoEM) now enable structure determination at atomic resolution with significantly reduced requirements for both sample quantity and purity. Combined with recent developments in gene editing, these advances open the door to structure determination and structural proteomics of macromolecular complexes enriched directly from P. falciparum parasites. Furthermore, the combination of cryoEM with the rapidly emerging use of in situ cryo electron tomography (cryoET) to directly visualize ultrastructures and protein complexes in the native cellular context will yield exciting new insights into the molecular machinery underpinning malaria parasite biology and pathogenesis." @default.
- W4200379904 created "2021-12-31" @default.
- W4200379904 creator A5024391384 @default.
- W4200379904 creator A5031801456 @default.
- W4200379904 creator A5049610765 @default.
- W4200379904 date "2021-12-01" @default.
- W4200379904 modified "2023-10-17" @default.
- W4200379904 title "Structural parasitology of the malaria parasite Plasmodium falciparum" @default.
- W4200379904 cites W1596563064 @default.
- W4200379904 cites W1890431460 @default.
- W4200379904 cites W1919302209 @default.
- W4200379904 cites W195201687 @default.
- W4200379904 cites W1967015536 @default.
- W4200379904 cites W1974978266 @default.
- W4200379904 cites W1984080130 @default.
- W4200379904 cites W2000122627 @default.
- W4200379904 cites W2003470884 @default.
- W4200379904 cites W2007732687 @default.
- W4200379904 cites W2009600663 @default.
- W4200379904 cites W2011665065 @default.
- W4200379904 cites W2013817482 @default.
- W4200379904 cites W2016314394 @default.
- W4200379904 cites W2037606550 @default.
- W4200379904 cites W2039175603 @default.
- W4200379904 cites W2039735909 @default.
- W4200379904 cites W2043891526 @default.
- W4200379904 cites W2049964978 @default.
- W4200379904 cites W2055730063 @default.
- W4200379904 cites W2056299698 @default.
- W4200379904 cites W2062579188 @default.
- W4200379904 cites W2074543807 @default.
- W4200379904 cites W2088822039 @default.
- W4200379904 cites W2089024353 @default.
- W4200379904 cites W2100455255 @default.
- W4200379904 cites W2104234755 @default.
- W4200379904 cites W2111780819 @default.
- W4200379904 cites W2117756276 @default.
- W4200379904 cites W2124675604 @default.
- W4200379904 cites W2125214575 @default.
- W4200379904 cites W2130264012 @default.
- W4200379904 cites W2132923209 @default.
- W4200379904 cites W2138390185 @default.
- W4200379904 cites W2143279537 @default.
- W4200379904 cites W2149360962 @default.
- W4200379904 cites W2151383900 @default.
- W4200379904 cites W2154609189 @default.
- W4200379904 cites W2162684905 @default.
- W4200379904 cites W2164659462 @default.
- W4200379904 cites W2165449806 @default.
- W4200379904 cites W2167868583 @default.
- W4200379904 cites W2212589734 @default.
- W4200379904 cites W2235248450 @default.
- W4200379904 cites W2278831064 @default.
- W4200379904 cites W2279402243 @default.
- W4200379904 cites W2328799122 @default.
- W4200379904 cites W2416387409 @default.
- W4200379904 cites W2475032147 @default.
- W4200379904 cites W2559997082 @default.
- W4200379904 cites W2587625522 @default.
- W4200379904 cites W2593511418 @default.
- W4200379904 cites W2613934809 @default.
- W4200379904 cites W2621796664 @default.
- W4200379904 cites W2744245504 @default.
- W4200379904 cites W2765383168 @default.
- W4200379904 cites W2773278544 @default.
- W4200379904 cites W2787027993 @default.
- W4200379904 cites W2787540286 @default.
- W4200379904 cites W2791354025 @default.
- W4200379904 cites W2792220024 @default.
- W4200379904 cites W2797011957 @default.
- W4200379904 cites W2883886095 @default.
- W4200379904 cites W2888208011 @default.
- W4200379904 cites W2903613121 @default.
- W4200379904 cites W2921332072 @default.
- W4200379904 cites W2950967305 @default.
- W4200379904 cites W2953320394 @default.
- W4200379904 cites W2955683107 @default.
- W4200379904 cites W2957093526 @default.
- W4200379904 cites W2963372443 @default.
- W4200379904 cites W2966796608 @default.
- W4200379904 cites W2977933365 @default.
- W4200379904 cites W2990430418 @default.
- W4200379904 cites W2990714798 @default.
- W4200379904 cites W2996870716 @default.
- W4200379904 cites W2999528257 @default.
- W4200379904 cites W3003776813 @default.
- W4200379904 cites W3024513041 @default.
- W4200379904 cites W3025920658 @default.
- W4200379904 cites W3046809066 @default.
- W4200379904 cites W3083406432 @default.
- W4200379904 cites W3092921638 @default.
- W4200379904 cites W3108495343 @default.
- W4200379904 cites W3117048947 @default.
- W4200379904 cites W3118289127 @default.
- W4200379904 cites W3123664588 @default.
- W4200379904 cites W3127326657 @default.
- W4200379904 cites W3127722007 @default.
- W4200379904 cites W3131760520 @default.
- W4200379904 cites W3164248691 @default.
- W4200379904 cites W3164812140 @default.