Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200386543> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4200386543 abstract "Background Iron (Fe) is traditionally supplemented in poultry and swine diets using inorganic forms (e.g. sulfates, oxides). However, research suggests that organic sources are more beneficial due to greater bioavailability. In this paper, we present results from four studies aimed at assessing ferric citrate (CI-FER™, Akeso Biomedical Inc., Burlington, MA, USA) as a safe and effective source of Fe for broilers and piglets. Methods A total of four studies were performed in Germany following standard farming practices for each species. One study in day-old broiler chicks and one study in weaned piglets were designed as target animal safety studies where animals were randomly allocated to one of three treatment groups: a negative control group, the proposed dose group and a multifold dose group. Broilers and pigs were fed the experimental diets for 35 and 42 days, respectively. In each study, average daily feed intake, average daily weight gain and feed conversion ratio were measured, and blood samples were taken at study end for routine biochemistry and haematology. The other two studies were designed to evaluate different sources of dietary Fe for weaned piglets bred and managed under standard farm conditions. All piglets received routine Fe injections (200 mg Fe dextran, intramuscular) on day 3 of age, as well as the experimental diets for 42 days. In both studies, performance parameters were measured. In one study, Fe digestibility and serum Fe, superoxide dismutase and haptoglobin were also measured. In all studies, the general health status of the animals was monitored daily and all culls and mortality recorded. Each study followed a complete randomised block design. Results In broilers, ferric citrate was well tolerated up to 2,000 mg/kg feed (×10 the recommended inclusion rate) and no adverse effects on growth, blood parameters or mortality were observed. In piglets, ferric citrate was well tolerated up to 5,000 mg/kg feed (×10 the recommended inclusion rate) with no adverse effects on growth, blood parameters or mortality. In addition, piglets fed ferric citrate performed significantly better than animals fed the negative control diet (containing only endogenous Fe) and those fed inorganic forms of Fe. Moreover, piglets fed ferric citrate demonstrated improved Fe digestibility and improved oxidative status. Altogether, these findings show that ferric citrate is a safe and easily digestible source of dietary Fe for broilers and piglets." @default.
- W4200386543 created "2021-12-31" @default.
- W4200386543 date "2021-12-22" @default.
- W4200386543 modified "2023-09-26" @default.
- W4200386543 title "Supplemental Information 5: Author checklist." @default.
- W4200386543 doi "https://doi.org/10.7717/peerj.12636/supp-5" @default.
- W4200386543 hasPublicationYear "2021" @default.
- W4200386543 type Work @default.
- W4200386543 citedByCount "0" @default.
- W4200386543 crossrefType "component" @default.
- W4200386543 hasBestOaLocation W42003865431 @default.
- W4200386543 hasConcept C126322002 @default.
- W4200386543 hasConcept C140793950 @default.
- W4200386543 hasConcept C147583825 @default.
- W4200386543 hasConcept C150903083 @default.
- W4200386543 hasConcept C206396517 @default.
- W4200386543 hasConcept C22830521 @default.
- W4200386543 hasConcept C2777417653 @default.
- W4200386543 hasConcept C2778248108 @default.
- W4200386543 hasConcept C2780084898 @default.
- W4200386543 hasConcept C2780289900 @default.
- W4200386543 hasConcept C2780320433 @default.
- W4200386543 hasConcept C2780959883 @default.
- W4200386543 hasConcept C42972112 @default.
- W4200386543 hasConcept C71924100 @default.
- W4200386543 hasConcept C86803240 @default.
- W4200386543 hasConceptScore W4200386543C126322002 @default.
- W4200386543 hasConceptScore W4200386543C140793950 @default.
- W4200386543 hasConceptScore W4200386543C147583825 @default.
- W4200386543 hasConceptScore W4200386543C150903083 @default.
- W4200386543 hasConceptScore W4200386543C206396517 @default.
- W4200386543 hasConceptScore W4200386543C22830521 @default.
- W4200386543 hasConceptScore W4200386543C2777417653 @default.
- W4200386543 hasConceptScore W4200386543C2778248108 @default.
- W4200386543 hasConceptScore W4200386543C2780084898 @default.
- W4200386543 hasConceptScore W4200386543C2780289900 @default.
- W4200386543 hasConceptScore W4200386543C2780320433 @default.
- W4200386543 hasConceptScore W4200386543C2780959883 @default.
- W4200386543 hasConceptScore W4200386543C42972112 @default.
- W4200386543 hasConceptScore W4200386543C71924100 @default.
- W4200386543 hasConceptScore W4200386543C86803240 @default.
- W4200386543 hasLocation W42003865431 @default.
- W4200386543 hasOpenAccess W4200386543 @default.
- W4200386543 hasPrimaryLocation W42003865431 @default.
- W4200386543 hasRelatedWork W12099772 @default.
- W4200386543 hasRelatedWork W14162785 @default.
- W4200386543 hasRelatedWork W14626305 @default.
- W4200386543 hasRelatedWork W16136096 @default.
- W4200386543 hasRelatedWork W362691 @default.
- W4200386543 hasRelatedWork W4935125 @default.
- W4200386543 hasRelatedWork W6790760 @default.
- W4200386543 hasRelatedWork W7229153 @default.
- W4200386543 hasRelatedWork W7416997 @default.
- W4200386543 hasRelatedWork W8083787 @default.
- W4200386543 isParatext "false" @default.
- W4200386543 isRetracted "false" @default.
- W4200386543 workType "paratext" @default.