FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200398428> ?p ?o ?g. }

• W4200398428 endingPage "219" @default.
• W4200398428 startingPage "210" @default.
• W4200398428 abstract "Our current investigation comprises the synthesis and pharmacological impact of bromelain copper nanoparticles (BrCuNP) against diabetes mellitus (DM) and associated ischemia/reperfusion (I/R) – induced myocardial infarction. Bromelain is a proteolytic enzyme obtained from Ananas comosus L. Merr., which has blood platelet aggregation inhibiting and arterial thrombolytic potential. Moreover, copper is well-known to facilitate glucose metabolism and strengthen cardiac muscle and antioxidant activity; although, chronic or long-term exposure to high doses of copper may lead to copperiedus. To restrict these potential hazards, we synthesized herbal nano-formulation which convincingly indicated the improved primordial therapeutic potential of copper by reformulating the treatment carrier with bromelain, resulting in facile synthesis of BrCuNP. DM was induced by administration of double cycle repetitive dose of low dose streptozotocin (20 mg/kg, i.p.) in high-fat diet- fed animals. DM and associated myocardial I/R injury were estimated by increased serum levels of total cholesterol, low-density lipoprotein, very low-density lipoprotein, lactate dehydrogenase, creatine kinase myocardial band, cardiac troponin, thiobarbituric acid reactive substances, tumor necrosis factor α, interleukin 6, and reduced serum level of high-density lipoprotein and nitrite/nitrate concentration. However, treatment with BrCuNP ameliorates various serum biomarkers by approving cardioprotective potential against DM- and I/R-associated injury. Furthermore, upturn of histopathological changes were observed in cardiac tissue of BrCuNP-treated rats in comparison to disease models." @default.
• W4200398428 created "2021-12-31" @default.
• W4200398428 creator A5016338755 @default.
• W4200398428 creator A5031637107 @default.
• W4200398428 creator A5038574717 @default.
• W4200398428 creator A5058262943 @default.
• W4200398428 creator A5085853972 @default.
• W4200398428 creator A5090827915 @default.
• W4200398428 date "2022-03-01" @default.
• W4200398428 modified "2023-10-16" @default.
• W4200398428 title "Facile synthesis of bromelain copper nanoparticles to improve the primordial therapeutic potential of copper against acute myocardial infarction in diabetic rats" @default.
• W4200398428 cites W1813115710 @default.
• W4200398428 cites W1915983093 @default.
• W4200398428 cites W1963821409 @default.
• W4200398428 cites W1973860724 @default.
• W4200398428 cites W2005066650 @default.
• W4200398428 cites W2006370100 @default.
• W4200398428 cites W2031871255 @default.
• W4200398428 cites W2035129904 @default.
• W4200398428 cites W2090415737 @default.
• W4200398428 cites W2104969665 @default.
• W4200398428 cites W2111296715 @default.
• W4200398428 cites W2112531993 @default.
• W4200398428 cites W2147675653 @default.
• W4200398428 cites W2172016746 @default.
• W4200398428 cites W2314093755 @default.
• W4200398428 cites W2337938280 @default.
• W4200398428 cites W2346507930 @default.
• W4200398428 cites W2409181047 @default.
• W4200398428 cites W2480909796 @default.
• W4200398428 cites W2528451823 @default.
• W4200398428 cites W2580537586 @default.
• W4200398428 cites W2620079766 @default.
• W4200398428 cites W2736036657 @default.
• W4200398428 cites W2740251705 @default.
• W4200398428 cites W2793411171 @default.
• W4200398428 cites W2794439438 @default.
• W4200398428 cites W2809376706 @default.
• W4200398428 cites W2809958435 @default.
• W4200398428 cites W2890699547 @default.
• W4200398428 cites W2900053361 @default.
• W4200398428 cites W2900601576 @default.
• W4200398428 cites W2911663503 @default.
• W4200398428 cites W2927993870 @default.
• W4200398428 cites W2987185629 @default.
• W4200398428 cites W3003630972 @default.
• W4200398428 cites W3085298651 @default.
• W4200398428 doi "https://doi.org/10.1139/cjpp-2021-0129" @default.
• W4200398428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34910610" @default.
• W4200398428 hasPublicationYear "2022" @default.
• W4200398428 type Work @default.
• W4200398428 citedByCount "6" @default.
• W4200398428 countsByYear W42003984282022 @default.
• W4200398428 countsByYear W42003984282023 @default.
• W4200398428 crossrefType "journal-article" @default.
• W4200398428 hasAuthorship W4200398428A5016338755 @default.
• W4200398428 hasAuthorship W4200398428A5031637107 @default.
• W4200398428 hasAuthorship W4200398428A5038574717 @default.
• W4200398428 hasAuthorship W4200398428A5058262943 @default.
• W4200398428 hasAuthorship W4200398428A5085853972 @default.
• W4200398428 hasAuthorship W4200398428A5090827915 @default.
• W4200398428 hasConcept C126322002 @default.
• W4200398428 hasConcept C134018914 @default.
• W4200398428 hasConcept C181199279 @default.
• W4200398428 hasConcept C185592680 @default.
• W4200398428 hasConcept C2777318727 @default.
• W4200398428 hasConcept C2777504301 @default.
• W4200398428 hasConcept C2778004101 @default.
• W4200398428 hasConcept C2780829032 @default.
• W4200398428 hasConcept C36880943 @default.
• W4200398428 hasConcept C500558357 @default.
• W4200398428 hasConcept C55493867 @default.
• W4200398428 hasConcept C555293320 @default.
• W4200398428 hasConcept C71924100 @default.
• W4200398428 hasConcept C98274493 @default.
• W4200398428 hasConceptScore W4200398428C126322002 @default.
• W4200398428 hasConceptScore W4200398428C134018914 @default.
• W4200398428 hasConceptScore W4200398428C181199279 @default.
• W4200398428 hasConceptScore W4200398428C185592680 @default.
• W4200398428 hasConceptScore W4200398428C2777318727 @default.
• W4200398428 hasConceptScore W4200398428C2777504301 @default.
• W4200398428 hasConceptScore W4200398428C2778004101 @default.
• W4200398428 hasConceptScore W4200398428C2780829032 @default.
• W4200398428 hasConceptScore W4200398428C36880943 @default.
• W4200398428 hasConceptScore W4200398428C500558357 @default.
• W4200398428 hasConceptScore W4200398428C55493867 @default.
• W4200398428 hasConceptScore W4200398428C555293320 @default.
• W4200398428 hasConceptScore W4200398428C71924100 @default.
• W4200398428 hasConceptScore W4200398428C98274493 @default.
• W4200398428 hasIssue "3" @default.
• W4200398428 hasLocation W42003984281 @default.
• W4200398428 hasLocation W42003984282 @default.
• W4200398428 hasOpenAccess W4200398428 @default.
• W4200398428 hasPrimaryLocation W42003984281 @default.
• W4200398428 hasRelatedWork W1975268474 @default.
• W4200398428 hasRelatedWork W2015555338 @default.
• W4200398428 hasRelatedWork W2036847398 @default.
• W4200398428 hasRelatedWork W2081217615 @default.

• next