Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200399807> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4200399807 abstract "To investigate the clinical manifestations of orbital involvement in a large cohort of Chinese patients with IgG4-related disease (IgG4-RD).A total of 573 patients with IgG4-related disease were included. We described and compared the demographic, clinical, laboratory and histopathologic findings from 314 patients with IgG4-related ophthalmic disease (IgG4-ROD) and 259 with extra-ophthalmic IgG4-RD.Male predominance was found significant in extra-ophthalmic IgG4-RD only. Patients with IgG4-ROD showed younger age at diagnosis and longer duration from onset till diagnosis. In patients with extra-ophthalmic IgG4-RD, the most commonly involved extra-ophthalmic organ was pancreas; while in IgG4-ROD patients, salivary gland was most frequently affected. Multivariate analysis exhibited IgG4-ROD was associated with allergy history, higher serum IgG4/IgG ratio, multiple organs involvement and sialoadenitis. Orbital images were reviewed in 173 (55.1%) IgG4-ROD patients. Fifty-one (29.5%) patients had multiple lesions. Lacrimal gland involvement was detected in 151 (87.3%) patients, followed by extraocular muscles (40, 23.1%), other orbital soft tissue (40, 23.1%) and trigeminal nerve (8, 4.6%). Biopsy was performed from various organs in 390 cases. A dense lymphoplasmacytic infiltration and fibrosis were the main feature in orbital specimens. Storiform fibrosis and obliterative phlebitis were absent in lacrimal gland.Lacrimal gland involvement was the most common orbital manifestation of IgG4-ROD. Patients with IgG4-ROD showed different characteristic in demographic, clinical, laboratory findings compared to patients with extra-ophthalmic IgG4-RD. These features might indicate potential differences in the pathogenesis of these two subgroups of IgG4-RD." @default.
- W4200399807 created "2021-12-31" @default.
- W4200399807 creator A5006759432 @default.
- W4200399807 creator A5007184871 @default.
- W4200399807 creator A5024716499 @default.
- W4200399807 creator A5026841517 @default.
- W4200399807 creator A5027079857 @default.
- W4200399807 creator A5048371164 @default.
- W4200399807 creator A5058333204 @default.
- W4200399807 creator A5063850144 @default.
- W4200399807 creator A5065771969 @default.
- W4200399807 creator A5070795303 @default.
- W4200399807 creator A5089853906 @default.
- W4200399807 date "2021-12-01" @default.
- W4200399807 modified "2023-09-26" @default.
- W4200399807 title "Ophthalmic involvement disparities in clinical characteristics of IgG4-related disease: a retrospective study of 573 patients" @default.
- W4200399807 cites W1891160624 @default.
- W4200399807 cites W2075300336 @default.
- W4200399807 cites W2108302885 @default.
- W4200399807 cites W2133763046 @default.
- W4200399807 cites W2140390659 @default.
- W4200399807 cites W2192872568 @default.
- W4200399807 cites W2758287922 @default.
- W4200399807 cites W2787136837 @default.
- W4200399807 cites W2808855218 @default.
- W4200399807 cites W2904681499 @default.
- W4200399807 cites W2906835839 @default.
- W4200399807 cites W2911475862 @default.
- W4200399807 cites W2913417984 @default.
- W4200399807 cites W2914871644 @default.
- W4200399807 cites W2955638605 @default.
- W4200399807 cites W2993526648 @default.
- W4200399807 cites W3035551419 @default.
- W4200399807 cites W3037425728 @default.
- W4200399807 cites W3081503639 @default.
- W4200399807 cites W4226001314 @default.
- W4200399807 doi "https://doi.org/10.1186/s12886-021-02210-z" @default.
- W4200399807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34961492" @default.
- W4200399807 hasPublicationYear "2021" @default.
- W4200399807 type Work @default.
- W4200399807 citedByCount "2" @default.
- W4200399807 countsByYear W42003998072022 @default.
- W4200399807 countsByYear W42003998072023 @default.
- W4200399807 crossrefType "journal-article" @default.
- W4200399807 hasAuthorship W4200399807A5006759432 @default.
- W4200399807 hasAuthorship W4200399807A5007184871 @default.
- W4200399807 hasAuthorship W4200399807A5024716499 @default.
- W4200399807 hasAuthorship W4200399807A5026841517 @default.
- W4200399807 hasAuthorship W4200399807A5027079857 @default.
- W4200399807 hasAuthorship W4200399807A5048371164 @default.
- W4200399807 hasAuthorship W4200399807A5058333204 @default.
- W4200399807 hasAuthorship W4200399807A5063850144 @default.
- W4200399807 hasAuthorship W4200399807A5065771969 @default.
- W4200399807 hasAuthorship W4200399807A5070795303 @default.
- W4200399807 hasAuthorship W4200399807A5089853906 @default.
- W4200399807 hasBestOaLocation W42003998071 @default.
- W4200399807 hasConcept C118487528 @default.
- W4200399807 hasConcept C142724271 @default.
- W4200399807 hasConcept C167135981 @default.
- W4200399807 hasConcept C2775934546 @default.
- W4200399807 hasConcept C2776807875 @default.
- W4200399807 hasConcept C2778650826 @default.
- W4200399807 hasConcept C2779298748 @default.
- W4200399807 hasConcept C2780224187 @default.
- W4200399807 hasConcept C2780559512 @default.
- W4200399807 hasConcept C71924100 @default.
- W4200399807 hasConceptScore W4200399807C118487528 @default.
- W4200399807 hasConceptScore W4200399807C142724271 @default.
- W4200399807 hasConceptScore W4200399807C167135981 @default.
- W4200399807 hasConceptScore W4200399807C2775934546 @default.
- W4200399807 hasConceptScore W4200399807C2776807875 @default.
- W4200399807 hasConceptScore W4200399807C2778650826 @default.
- W4200399807 hasConceptScore W4200399807C2779298748 @default.
- W4200399807 hasConceptScore W4200399807C2780224187 @default.
- W4200399807 hasConceptScore W4200399807C2780559512 @default.
- W4200399807 hasConceptScore W4200399807C71924100 @default.
- W4200399807 hasIssue "1" @default.
- W4200399807 hasLocation W42003998071 @default.
- W4200399807 hasLocation W42003998072 @default.
- W4200399807 hasLocation W42003998073 @default.
- W4200399807 hasLocation W42003998074 @default.
- W4200399807 hasOpenAccess W4200399807 @default.
- W4200399807 hasPrimaryLocation W42003998071 @default.
- W4200399807 hasRelatedWork W1979173488 @default.
- W4200399807 hasRelatedWork W2014279656 @default.
- W4200399807 hasRelatedWork W2023170279 @default.
- W4200399807 hasRelatedWork W2027352144 @default.
- W4200399807 hasRelatedWork W2941838460 @default.
- W4200399807 hasRelatedWork W2981029773 @default.
- W4200399807 hasRelatedWork W3183606730 @default.
- W4200399807 hasRelatedWork W4200399807 @default.
- W4200399807 hasRelatedWork W4220883392 @default.
- W4200399807 hasRelatedWork W4313479980 @default.
- W4200399807 hasVolume "21" @default.
- W4200399807 isParatext "false" @default.
- W4200399807 isRetracted "false" @default.
- W4200399807 workType "article" @default.