Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200400093> ?p ?o ?g. }
- W4200400093 endingPage "131205" @default.
- W4200400093 startingPage "131205" @default.
- W4200400093 abstract "Surface-enhanced Raman spectroscopy (SERS) has attracted enormous interests as a biological sensing technique. However, the wide application of SERS technique suffers from the limitation of sensitivity, uniformity and universality for the analytes. Herein, a graphene-nanopyramids hybrid SERS system with high uniformity and sensitivity was used to label-freely detect analytes at different scales. Colloidal lithography and modern semiconductor nanofabrication process were employed for the fabrication of wafer-scale highly-ordered array of Au nanopyramids, which ensures the uniformity of the system. The graphene layer not only plays a role of biology-compatible supporting layer for analytes but also further enhances the Raman signals and facilitates the quantitative analysis capability of the hybrid system as an intensity gauge. For nanoscale chemical and protein molecules including Rhodamine 6G (R6G), methylene blue (MB), catalase and lysozyme with concentrations lower than 10−10 M, clear SERS signals can be obtained with analytical enhancement factors (EFs) of ~109 for R6G and MB. For micron-scale analytes, Raman fingerprints of cells, i.e. erythrocyte and leukocyte have been obtained. Moreover, using statistical principal component analysis method, one can easily distinguish different analytes based on their Raman fingerprints. The experiment results of EF are in good agreement with the theoretical values predicted by finite-difference time-domain simulation. Such a wafer-scale, highly uniform and universal system will certainly enable the wider application of SERS in multiscale label-free detection of chemicals, proteins and cells, etc. with high sensitivity and specificity." @default.
- W4200400093 created "2021-12-31" @default.
- W4200400093 creator A5000612349 @default.
- W4200400093 creator A5004465849 @default.
- W4200400093 creator A5007529205 @default.
- W4200400093 creator A5014216586 @default.
- W4200400093 creator A5018269983 @default.
- W4200400093 creator A5020227993 @default.
- W4200400093 creator A5021787665 @default.
- W4200400093 creator A5028796651 @default.
- W4200400093 creator A5031165365 @default.
- W4200400093 creator A5035843058 @default.
- W4200400093 creator A5041436817 @default.
- W4200400093 creator A5047187328 @default.
- W4200400093 creator A5068744771 @default.
- W4200400093 creator A5072118178 @default.
- W4200400093 creator A5075275821 @default.
- W4200400093 creator A5076617776 @default.
- W4200400093 creator A5085381331 @default.
- W4200400093 date "2022-03-01" @default.
- W4200400093 modified "2023-10-18" @default.
- W4200400093 title "Highly sensitive label-free detection of analytes at different scales using uniform graphene-nanopyramids hybrid SERS system" @default.
- W4200400093 cites W1973837452 @default.
- W4200400093 cites W1989941207 @default.
- W4200400093 cites W2014159097 @default.
- W4200400093 cites W2021136655 @default.
- W4200400093 cites W2024092247 @default.
- W4200400093 cites W2038068130 @default.
- W4200400093 cites W2038754799 @default.
- W4200400093 cites W2041280299 @default.
- W4200400093 cites W2042647070 @default.
- W4200400093 cites W2073472738 @default.
- W4200400093 cites W2074880343 @default.
- W4200400093 cites W2083004238 @default.
- W4200400093 cites W2087090334 @default.
- W4200400093 cites W2088154743 @default.
- W4200400093 cites W2093759230 @default.
- W4200400093 cites W2098943829 @default.
- W4200400093 cites W2129719133 @default.
- W4200400093 cites W2135487480 @default.
- W4200400093 cites W2138688250 @default.
- W4200400093 cites W2140934822 @default.
- W4200400093 cites W2156920977 @default.
- W4200400093 cites W2299637118 @default.
- W4200400093 cites W2301954252 @default.
- W4200400093 cites W2312826039 @default.
- W4200400093 cites W2320545600 @default.
- W4200400093 cites W2395724393 @default.
- W4200400093 cites W2592697518 @default.
- W4200400093 cites W2622418749 @default.
- W4200400093 cites W2730282942 @default.
- W4200400093 cites W2751255504 @default.
- W4200400093 cites W2795764155 @default.
- W4200400093 cites W2797445881 @default.
- W4200400093 cites W2883094376 @default.
- W4200400093 cites W2906613092 @default.
- W4200400093 cites W2911016303 @default.
- W4200400093 cites W2911349318 @default.
- W4200400093 cites W3012845972 @default.
- W4200400093 cites W3046342366 @default.
- W4200400093 cites W3049764105 @default.
- W4200400093 doi "https://doi.org/10.1016/j.snb.2021.131205" @default.
- W4200400093 hasPublicationYear "2022" @default.
- W4200400093 type Work @default.
- W4200400093 citedByCount "10" @default.
- W4200400093 countsByYear W42004000932022 @default.
- W4200400093 countsByYear W42004000932023 @default.
- W4200400093 crossrefType "journal-article" @default.
- W4200400093 hasAuthorship W4200400093A5000612349 @default.
- W4200400093 hasAuthorship W4200400093A5004465849 @default.
- W4200400093 hasAuthorship W4200400093A5007529205 @default.
- W4200400093 hasAuthorship W4200400093A5014216586 @default.
- W4200400093 hasAuthorship W4200400093A5018269983 @default.
- W4200400093 hasAuthorship W4200400093A5020227993 @default.
- W4200400093 hasAuthorship W4200400093A5021787665 @default.
- W4200400093 hasAuthorship W4200400093A5028796651 @default.
- W4200400093 hasAuthorship W4200400093A5031165365 @default.
- W4200400093 hasAuthorship W4200400093A5035843058 @default.
- W4200400093 hasAuthorship W4200400093A5041436817 @default.
- W4200400093 hasAuthorship W4200400093A5047187328 @default.
- W4200400093 hasAuthorship W4200400093A5068744771 @default.
- W4200400093 hasAuthorship W4200400093A5072118178 @default.
- W4200400093 hasAuthorship W4200400093A5075275821 @default.
- W4200400093 hasAuthorship W4200400093A5076617776 @default.
- W4200400093 hasAuthorship W4200400093A5085381331 @default.
- W4200400093 hasConcept C10390740 @default.
- W4200400093 hasConcept C120665830 @default.
- W4200400093 hasConcept C121332964 @default.
- W4200400093 hasConcept C136525101 @default.
- W4200400093 hasConcept C142724271 @default.
- W4200400093 hasConcept C160671074 @default.
- W4200400093 hasConcept C160756335 @default.
- W4200400093 hasConcept C162117346 @default.
- W4200400093 hasConcept C171250308 @default.
- W4200400093 hasConcept C178790620 @default.
- W4200400093 hasConcept C185592680 @default.
- W4200400093 hasConcept C192562407 @default.
- W4200400093 hasConcept C204787440 @default.