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- W4200412145 abstract "Rampant use of antibiotics in human and veterinary medicine with the paucity in the discovery of novel antibiotics has pushed the clinically relevant microbes to develop long-term and indeed a never-ending threat of antimicrobial resistance. As a result, the infections pertinent to gastrointestinal, pulmonary/air-way, and urogenital tract are posing a real challenge to cure by conventional antibiotics. As more antibiotics are rendered ineffective to curb infectious diseases, it is crucial to unravel novel antimicrobials to fight against resistant infections. Today, several advanced strategies, such as antimicrobial peptides, bacteriophages, endolysins, nanoparticles, engineered peptides, antibodies, and probiotics, have been put forth by the scientific community to combat difficult-to-treat-infections with antibiotics. Amidst the several alternatives to antibiotics, the present chapter aims to highlight the role of probiotics in confronting antibiotic-resistant pathogens due to their multifaceted inhibitory action on pathogenic microbes. Probiotic-based remedial approach targets both pathogens (superbug) and host. The mechanisms of actions of probiotics against multidrug superbugs largely remain multifarious. The protective mode of probiotics against such infections is mediated by various antagonistic activities, such as antimicrobial, antibiofilm, antivirulence, antiquorum sensing, antiinvasive, antiadhesive, and antidrug resistance. Besides strengthening the epithelial barrier functioning, probiotics strengthen the host immune system by priming the immune cells to fight against superbugs. Owing to these beneficial effects, probiotics intervention through intragastric, intravaginal, and intranasal routes are widely evaluated as a promising strategy to curb the resistant infections of intestinal, urogenital/vaginal, and respiratory infections caused by antibiotic-resistant pathogens. In this context, the present chapter recapitulates the mechanism of action of probiotics while antagonizing the multidrug-resistant superbugs and their subsequent infections." @default.
- W4200412145 created "2021-12-31" @default.
- W4200412145 creator A5081396216 @default.
- W4200412145 creator A5083766161 @default.
- W4200412145 date "2022-01-01" @default.
- W4200412145 modified "2023-09-26" @default.
- W4200412145 title "Role of probiotics in infections with multidrug-resistant organisms" @default.
- W4200412145 cites W1588999779 @default.
- W4200412145 cites W1963808068 @default.
- W4200412145 cites W1964263490 @default.
- W4200412145 cites W1964954110 @default.
- W4200412145 cites W1966072666 @default.
- W4200412145 cites W2004142936 @default.
- W4200412145 cites W2009755654 @default.
- W4200412145 cites W2015564190 @default.
- W4200412145 cites W2016865034 @default.
- W4200412145 cites W2018491677 @default.
- W4200412145 cites W2019742352 @default.
- W4200412145 cites W2022617341 @default.
- W4200412145 cites W2026577253 @default.
- W4200412145 cites W2034662430 @default.
- W4200412145 cites W2051024501 @default.
- W4200412145 cites W2053944820 @default.
- W4200412145 cites W2057031142 @default.
- W4200412145 cites W2061195394 @default.
- W4200412145 cites W2063692880 @default.
- W4200412145 cites W2078781178 @default.
- W4200412145 cites W2079236702 @default.
- W4200412145 cites W2086206082 @default.
- W4200412145 cites W2095017924 @default.
- W4200412145 cites W2096282426 @default.
- W4200412145 cites W2118357516 @default.
- W4200412145 cites W2121747156 @default.
- W4200412145 cites W2126492324 @default.
- W4200412145 cites W2128414896 @default.
- W4200412145 cites W2133379595 @default.
- W4200412145 cites W2151372451 @default.
- W4200412145 cites W2160747323 @default.
- W4200412145 cites W2163366375 @default.
- W4200412145 cites W2165966813 @default.
- W4200412145 cites W2175097395 @default.
- W4200412145 cites W2192215408 @default.
- W4200412145 cites W2239738725 @default.
- W4200412145 cites W2321514759 @default.
- W4200412145 cites W2345300303 @default.
- W4200412145 cites W2487171814 @default.
- W4200412145 cites W2537895025 @default.
- W4200412145 cites W2549976565 @default.
- W4200412145 cites W2581345147 @default.
- W4200412145 cites W2587064316 @default.
- W4200412145 cites W2601068128 @default.
- W4200412145 cites W2731461969 @default.
- W4200412145 cites W2737953146 @default.
- W4200412145 cites W2744700551 @default.
- W4200412145 cites W2760582990 @default.
- W4200412145 cites W2770654152 @default.
- W4200412145 cites W2784307328 @default.
- W4200412145 cites W2791571451 @default.
- W4200412145 cites W2793051982 @default.
- W4200412145 cites W2799537073 @default.
- W4200412145 cites W2799829750 @default.
- W4200412145 cites W2801910542 @default.
- W4200412145 cites W2803487426 @default.
- W4200412145 cites W2806070478 @default.
- W4200412145 cites W2807266621 @default.
- W4200412145 cites W2811435928 @default.
- W4200412145 cites W2896182701 @default.
- W4200412145 cites W2903347362 @default.
- W4200412145 cites W2909070987 @default.
- W4200412145 cites W2912354751 @default.
- W4200412145 cites W2913351284 @default.
- W4200412145 cites W2925399545 @default.
- W4200412145 cites W2933130235 @default.
- W4200412145 cites W2944886876 @default.
- W4200412145 cites W2945441327 @default.
- W4200412145 cites W2949897498 @default.
- W4200412145 cites W2958532943 @default.
- W4200412145 cites W2970234575 @default.
- W4200412145 cites W2972346588 @default.
- W4200412145 cites W2981955239 @default.
- W4200412145 cites W2982538900 @default.
- W4200412145 cites W2995761345 @default.
- W4200412145 cites W3004378989 @default.
- W4200412145 cites W3021515196 @default.
- W4200412145 cites W3037816944 @default.
- W4200412145 cites W3045191833 @default.
- W4200412145 cites W3048461040 @default.
- W4200412145 cites W4210498721 @default.
- W4200412145 doi "https://doi.org/10.1016/b978-0-12-823733-5.00004-0" @default.
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