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- W4200427801 abstract "Physical activity benefits both fitness and cognition. However, its effect on long-term memory is unclear. Successful memory involves not only remembering information over time but also keeping memories distinct and less confusing. The ability to separate similar experiences into distinct memories is one of the main features of episodic memory. In this work, we evaluated the effect of acute and chronic physical activity on a new task to assess spatial pattern separation in a 3D virtual reality environment. We manipulated the load of memory similarity and found that 25 minutes of cycling after encoding - but not before retrieval - was sufficient to improve similar, but not dissimilar memories, 24 hours after encoding. Furthermore, we found that participants who engaged in regular physical activity, but not sedentary subjects, showed memory for the similar condition the next day. Thus, physical activity could be a simple way to improve discrimination of spatial memories in humans." @default.
- W4200427801 created "2021-12-31" @default.
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- W4200427801 date "2021-12-14" @default.
- W4200427801 modified "2023-10-18" @default.
- W4200427801 title "Acute and chronic physical activity improve spatial pattern separation in humans" @default.
- W4200427801 doi "https://doi.org/10.1101/2021.12.13.472386" @default.
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