Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200435575> ?p ?o ?g. }
- W4200435575 endingPage "e12456" @default.
- W4200435575 startingPage "e12456" @default.
- W4200435575 abstract "Corynebacterium pseudotuberculosis is a Gram-positive facultative intracellular pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants, mastitis in dairy cattle, ulcerative lymphangitis in equines, and oedematous skin disease in buffalos. With the growing advance in high-throughput technologies, genomic studies have been carried out to explore the molecular basis of its virulence and pathogenicity. However, data large-scale functional genomics studies are necessary to complement genomics data and better understating the molecular basis of a given organism. Here we summarize, MS-based proteomics techniques and bioinformatics tools incorporated in genomic functional studies of C. pseudotuberculosis to discover the different patterns of protein modulation under distinct environmental conditions, and antigenic and drugs targets.In this study we performed an extensive search in Web of Science of original and relevant articles related to methods, strategy, technology, approaches, and bioinformatics tools focused on the functional study of the genome of C. pseudotuberculosis at the protein level.Here, we highlight the use of proteomics for understating several aspects of the physiology and pathogenesis of C. pseudotuberculosis at the protein level. The implementation and use of protocols, strategies, and proteomics approach to characterize the different subcellular fractions of the proteome of this pathogen. In addition, we have discussed the immunoproteomics, immunoinformatics and genetic tools employed to identify targets for immunoassays, drugs, and vaccines against C. pseudotuberculosis infection.In this review, we showed that the combination of proteomics and bioinformatics studies is a suitable strategy to elucidate the functional aspects of the C. pseudotuberculosis genome. Together, all information generated from these proteomics studies allowed expanding our knowledge about factors related to the pathophysiology of this pathogen." @default.
- W4200435575 created "2021-12-31" @default.
- W4200435575 creator A5017562043 @default.
- W4200435575 creator A5018158199 @default.
- W4200435575 creator A5065170435 @default.
- W4200435575 creator A5069429361 @default.
- W4200435575 date "2021-12-23" @default.
- W4200435575 modified "2023-10-16" @default.
- W4200435575 title "A journey through the Corynebacterium pseudotuberculosis proteome promotes insights into its functional genome" @default.
- W4200435575 cites W1177134112 @default.
- W4200435575 cites W127457810 @default.
- W4200435575 cites W140186901 @default.
- W4200435575 cites W1475074082 @default.
- W4200435575 cites W1537641994 @default.
- W4200435575 cites W1559693804 @default.
- W4200435575 cites W1571861186 @default.
- W4200435575 cites W1600326538 @default.
- W4200435575 cites W1761822939 @default.
- W4200435575 cites W185751362 @default.
- W4200435575 cites W1926460457 @default.
- W4200435575 cites W1935158889 @default.
- W4200435575 cites W1952551347 @default.
- W4200435575 cites W1965952876 @default.
- W4200435575 cites W1969248471 @default.
- W4200435575 cites W1969534656 @default.
- W4200435575 cites W1972375069 @default.
- W4200435575 cites W1972552473 @default.
- W4200435575 cites W1974585766 @default.
- W4200435575 cites W1981768599 @default.
- W4200435575 cites W1983554329 @default.
- W4200435575 cites W1986557523 @default.
- W4200435575 cites W1986887325 @default.
- W4200435575 cites W1987218429 @default.
- W4200435575 cites W1988642109 @default.
- W4200435575 cites W1989082176 @default.
- W4200435575 cites W1990882513 @default.
- W4200435575 cites W1997604729 @default.
- W4200435575 cites W2000671695 @default.
- W4200435575 cites W2001460112 @default.
- W4200435575 cites W2003199906 @default.
- W4200435575 cites W2003290131 @default.
- W4200435575 cites W2005095482 @default.
- W4200435575 cites W2005135379 @default.
- W4200435575 cites W2005191612 @default.
- W4200435575 cites W2006707827 @default.
- W4200435575 cites W2008241299 @default.
- W4200435575 cites W2009951837 @default.
- W4200435575 cites W2013038528 @default.
- W4200435575 cites W2018142194 @default.
- W4200435575 cites W2020228517 @default.
- W4200435575 cites W2020462542 @default.
- W4200435575 cites W2021497905 @default.
- W4200435575 cites W2022597868 @default.
- W4200435575 cites W2024609229 @default.
- W4200435575 cites W2026274850 @default.
- W4200435575 cites W2027404133 @default.
- W4200435575 cites W2031817672 @default.
- W4200435575 cites W2032663071 @default.
- W4200435575 cites W2035944542 @default.
- W4200435575 cites W2042111367 @default.
- W4200435575 cites W2043214808 @default.
- W4200435575 cites W2043545998 @default.
- W4200435575 cites W2043691606 @default.
- W4200435575 cites W2044678473 @default.
- W4200435575 cites W2045391217 @default.
- W4200435575 cites W2049835283 @default.
- W4200435575 cites W2056027400 @default.
- W4200435575 cites W2057587367 @default.
- W4200435575 cites W2067232676 @default.
- W4200435575 cites W2067863279 @default.
- W4200435575 cites W2068709070 @default.
- W4200435575 cites W2070377977 @default.
- W4200435575 cites W2075138494 @default.
- W4200435575 cites W2076573583 @default.
- W4200435575 cites W2077302483 @default.
- W4200435575 cites W2079727190 @default.
- W4200435575 cites W2084806647 @default.
- W4200435575 cites W2084866660 @default.
- W4200435575 cites W2087563064 @default.
- W4200435575 cites W2090481734 @default.
- W4200435575 cites W2090875160 @default.
- W4200435575 cites W2091839935 @default.
- W4200435575 cites W2092258760 @default.
- W4200435575 cites W2096495272 @default.
- W4200435575 cites W2097523781 @default.
- W4200435575 cites W2099980906 @default.
- W4200435575 cites W2100151882 @default.
- W4200435575 cites W2100793006 @default.
- W4200435575 cites W2107539594 @default.
- W4200435575 cites W2110714820 @default.
- W4200435575 cites W2112690862 @default.
- W4200435575 cites W2116272367 @default.
- W4200435575 cites W2117217301 @default.
- W4200435575 cites W2123211765 @default.
- W4200435575 cites W2124303345 @default.
- W4200435575 cites W2127697941 @default.
- W4200435575 cites W2128042434 @default.
- W4200435575 cites W2130833873 @default.