FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200437721> ?p ?o ?g. }

• W4200437721 endingPage "1185" @default.
• W4200437721 startingPage "1173" @default.
• W4200437721 abstract "Abstract Background Antimicrobial resistance has been recognised as a global threat with carbapenemase- producing-Enterobacteriaceae (CPE) as a prime example. CPE has similarities to COVID-19 where asymptomatic patients may be colonised representing a source for onward transmission. There are limited treatment options for CPE infection leading to poor outcomes and increased costs. Admission screening can prevent cross-transmission by pre-emptively isolating colonised patients. Objective We assess the relative cost-effectiveness of screening programmes compared with no- screening. Methods A microsimulation parameterised with NHS Scotland date was used to model scenarios of the prevalence of CPE colonised patients on admission. Screening strategies were (a) two-step screening involving a clinical risk assessment (CRA) checklist followed by microbiological testing of high-risk patients; and (b) universal screening. Strategies were considered with either culture or polymerase chain reaction (PCR) tests. All costs were reported in 2019 UK pounds with a healthcare system perspective. Results In the low prevalence scenario, no screening had the highest probability of cost-effectiveness. Among screening strategies, the two CRA screening options were the most likely to be cost-effective. Screening was more likely to be cost-effective than no screening in the prevalence of 1 CPE colonised in 500 admitted patients or more. There was substantial uncertainty with the probabilities rarely exceeding 40% and similar results between strategies. Screening reduced non-isolated bed-days and CPE colonisation. The cost of screening was low in relation to total costs. Conclusion The specificity of the CRA checklist was the parameter with the highest impact on the cost-effectiveness. Further primary data collection is needed to build models with less uncertainty in the parameters." @default.
• W4200437721 created "2021-12-31" @default.
• W4200437721 creator A5005336577 @default.
• W4200437721 creator A5011937800 @default.
• W4200437721 creator A5014846731 @default.
• W4200437721 creator A5040146643 @default.
• W4200437721 creator A5048192920 @default.
• W4200437721 creator A5056020076 @default.
• W4200437721 creator A5061139677 @default.
• W4200437721 creator A5069412942 @default.
• W4200437721 creator A5072214291 @default.
• W4200437721 creator A5086194680 @default.
• W4200437721 creator A5088126993 @default.
• W4200437721 date "2021-12-21" @default.
• W4200437721 modified "2023-09-30" @default.
• W4200437721 title "Probabilistic microsimulation to examine the cost-effectiveness of hospital admission screening strategies for carbapenemase-producing enterobacteriaceae (CPE) in the United Kingdom" @default.
• W4200437721 cites W1501030611 @default.
• W4200437721 cites W1895606344 @default.
• W4200437721 cites W1968471686 @default.
• W4200437721 cites W1981667259 @default.
• W4200437721 cites W1999789157 @default.
• W4200437721 cites W2078615887 @default.
• W4200437721 cites W2078845655 @default.
• W4200437721 cites W2083379102 @default.
• W4200437721 cites W2112947088 @default.
• W4200437721 cites W2118519564 @default.
• W4200437721 cites W2118778931 @default.
• W4200437721 cites W2131553265 @default.
• W4200437721 cites W2165699474 @default.
• W4200437721 cites W2176157669 @default.
• W4200437721 cites W2205644552 @default.
• W4200437721 cites W2517337009 @default.
• W4200437721 cites W2529931137 @default.
• W4200437721 cites W2579174706 @default.
• W4200437721 cites W2607194758 @default.
• W4200437721 cites W2757303946 @default.
• W4200437721 cites W2771344044 @default.
• W4200437721 cites W2773943145 @default.
• W4200437721 cites W2884943253 @default.
• W4200437721 cites W2887359797 @default.
• W4200437721 cites W2901183389 @default.
• W4200437721 cites W2918206043 @default.
• W4200437721 cites W2929636164 @default.
• W4200437721 cites W2946467275 @default.
• W4200437721 cites W2947107637 @default.
• W4200437721 cites W2954164407 @default.
• W4200437721 cites W3010226067 @default.
• W4200437721 doi "https://doi.org/10.1007/s10198-021-01419-5" @default.
• W4200437721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34932169" @default.
• W4200437721 hasPublicationYear "2021" @default.
• W4200437721 type Work @default.
• W4200437721 citedByCount "2" @default.
• W4200437721 countsByYear W42004377212023 @default.
• W4200437721 crossrefType "journal-article" @default.
• W4200437721 hasAuthorship W4200437721A5005336577 @default.
• W4200437721 hasAuthorship W4200437721A5011937800 @default.
• W4200437721 hasAuthorship W4200437721A5014846731 @default.
• W4200437721 hasAuthorship W4200437721A5040146643 @default.
• W4200437721 hasAuthorship W4200437721A5048192920 @default.
• W4200437721 hasAuthorship W4200437721A5056020076 @default.
• W4200437721 hasAuthorship W4200437721A5061139677 @default.
• W4200437721 hasAuthorship W4200437721A5069412942 @default.
• W4200437721 hasAuthorship W4200437721A5072214291 @default.
• W4200437721 hasAuthorship W4200437721A5086194680 @default.
• W4200437721 hasAuthorship W4200437721A5088126993 @default.
• W4200437721 hasBestOaLocation W42004377211 @default.
• W4200437721 hasConcept C112930515 @default.
• W4200437721 hasConcept C119599485 @default.
• W4200437721 hasConcept C127413603 @default.
• W4200437721 hasConcept C138816342 @default.
• W4200437721 hasConcept C151730666 @default.
• W4200437721 hasConcept C159110408 @default.
• W4200437721 hasConcept C177713679 @default.
• W4200437721 hasConcept C194828623 @default.
• W4200437721 hasConcept C22212356 @default.
• W4200437721 hasConcept C2779356329 @default.
• W4200437721 hasConcept C2780015235 @default.
• W4200437721 hasConcept C3019080777 @default.
• W4200437721 hasConcept C71924100 @default.
• W4200437721 hasConcept C761482 @default.
• W4200437721 hasConcept C86803240 @default.
• W4200437721 hasConceptScore W4200437721C112930515 @default.
• W4200437721 hasConceptScore W4200437721C119599485 @default.
• W4200437721 hasConceptScore W4200437721C127413603 @default.
• W4200437721 hasConceptScore W4200437721C138816342 @default.
• W4200437721 hasConceptScore W4200437721C151730666 @default.
• W4200437721 hasConceptScore W4200437721C159110408 @default.
• W4200437721 hasConceptScore W4200437721C177713679 @default.
• W4200437721 hasConceptScore W4200437721C194828623 @default.
• W4200437721 hasConceptScore W4200437721C22212356 @default.
• W4200437721 hasConceptScore W4200437721C2779356329 @default.
• W4200437721 hasConceptScore W4200437721C2780015235 @default.
• W4200437721 hasConceptScore W4200437721C3019080777 @default.
• W4200437721 hasConceptScore W4200437721C71924100 @default.
• W4200437721 hasConceptScore W4200437721C761482 @default.
• W4200437721 hasConceptScore W4200437721C86803240 @default.
• W4200437721 hasIssue "7" @default.
• W4200437721 hasLocation W42004377211 @default.

• next