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- W4200438304 abstract "Gluten is a complex of structure-building proteins founds in certain cereal grains including wheat, barley, and rye. Gluten-containing grains play an important role in food technology and have become the most widely consumed dietary components worldwide. The gluten content of wheat varieties has gradually increased over time, leading to a significant spread of gluten-related disorders (GRDs). Celiac disease (CeD), dermatitis herpetiformis (DH), gluten ataxia (GA) as autoimmune, wheat allergy (WA) as allergic and non-celiac gluten sensitivity (NCGS) as non-autoimmune-allergic diseases are the five main categories of GRDs. Each GRD occurs following specific pathophysiological responses to gluten, and recent advances have been made in unraveling each of these disorders’ pathogenic pathways. GRDs present with typical and atypical manifestations. Similar presentations of GRDs make their final diagnosis challenging. A long-life gluten-free diet (GFD) is the mainstay of GRDs treatment, warranting good health in the majority of patients. Regular monitoring and follow-up strategies include evaluating symptoms, assessing GFD adherence, and looking for disease complications are necessary for proper handling of GRDs." @default.
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- W4200438304 date "2022-01-01" @default.
- W4200438304 modified "2023-09-26" @default.
- W4200438304 title "Introduction" @default.
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- W4200438304 doi "https://doi.org/10.1016/b978-0-12-821846-4.00001-2" @default.
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