Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200438766> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4200438766 endingPage "414" @default.
- W4200438766 startingPage "407" @default.
- W4200438766 abstract "Introduction: Multiple factors contribute to increased risk of dehydration in amyotrophic lateral sclerosis (ALS), which contributes to shortened survival independent of nutritional status. The assessment of hydration by doubly labeled water is restricted due to the limited availability of this gold standard technique for clinical use. This prompted us to examine the utility of urine-specific gravity (USG) as a predictor of hydration need in ALS subjects. Material and Methods: Using data from a multicenter study of 80 ALS subjects with 250 visits, we conducted a secondary analysis of the original data set from doubly labeled water experiments. We used a cross-section of the data (one visit per 75 subjects) in the model selection step (“test set”), and a repeated measures analysis in the validation step with data from 63 subjects and 142 follow-up visits. The sensitivity to detect inadequate water turnover rate (a surrogate for water intake) was the goal of the predictive model presented for clinical use. Results and discussion: The final predictive model to estimate water requirement included USG, gender, body mass index, and the ALSFRS gross motor subscale score. We developed a best-fit equation to estimate water intake from USG, determine hydration status, and improve clinical care of real-world ALS subjects." @default.
- W4200438766 created "2021-12-31" @default.
- W4200438766 creator A5023627853 @default.
- W4200438766 creator A5049944904 @default.
- W4200438766 creator A5057215950 @default.
- W4200438766 creator A5063159901 @default.
- W4200438766 creator A5074766239 @default.
- W4200438766 creator A5075022413 @default.
- W4200438766 date "2021-12-17" @default.
- W4200438766 modified "2023-10-05" @default.
- W4200438766 title "Urine specific gravity to identify and predict hydration need in ALS" @default.
- W4200438766 cites W16413480 @default.
- W4200438766 cites W1823883969 @default.
- W4200438766 cites W1919406672 @default.
- W4200438766 cites W1977988586 @default.
- W4200438766 cites W1997921463 @default.
- W4200438766 cites W2025099429 @default.
- W4200438766 cites W2025147543 @default.
- W4200438766 cites W2030907336 @default.
- W4200438766 cites W2092771089 @default.
- W4200438766 cites W2108381339 @default.
- W4200438766 cites W2115758920 @default.
- W4200438766 cites W2119648350 @default.
- W4200438766 cites W2122461239 @default.
- W4200438766 cites W2140150532 @default.
- W4200438766 cites W2161938104 @default.
- W4200438766 cites W2184101038 @default.
- W4200438766 cites W2231450779 @default.
- W4200438766 cites W225398628 @default.
- W4200438766 cites W2606315231 @default.
- W4200438766 cites W2772331326 @default.
- W4200438766 cites W2989213907 @default.
- W4200438766 doi "https://doi.org/10.1080/21678421.2021.2013894" @default.
- W4200438766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34918583" @default.
- W4200438766 hasPublicationYear "2021" @default.
- W4200438766 type Work @default.
- W4200438766 citedByCount "0" @default.
- W4200438766 crossrefType "journal-article" @default.
- W4200438766 hasAuthorship W4200438766A5023627853 @default.
- W4200438766 hasAuthorship W4200438766A5049944904 @default.
- W4200438766 hasAuthorship W4200438766A5057215950 @default.
- W4200438766 hasAuthorship W4200438766A5063159901 @default.
- W4200438766 hasAuthorship W4200438766A5074766239 @default.
- W4200438766 hasAuthorship W4200438766A5075022413 @default.
- W4200438766 hasConcept C105795698 @default.
- W4200438766 hasConcept C126322002 @default.
- W4200438766 hasConcept C135760203 @default.
- W4200438766 hasConcept C20685875 @default.
- W4200438766 hasConcept C2779134260 @default.
- W4200438766 hasConcept C2780026642 @default.
- W4200438766 hasConcept C2780596555 @default.
- W4200438766 hasConcept C33923547 @default.
- W4200438766 hasConcept C40993552 @default.
- W4200438766 hasConcept C70410870 @default.
- W4200438766 hasConcept C71924100 @default.
- W4200438766 hasConceptScore W4200438766C105795698 @default.
- W4200438766 hasConceptScore W4200438766C126322002 @default.
- W4200438766 hasConceptScore W4200438766C135760203 @default.
- W4200438766 hasConceptScore W4200438766C20685875 @default.
- W4200438766 hasConceptScore W4200438766C2779134260 @default.
- W4200438766 hasConceptScore W4200438766C2780026642 @default.
- W4200438766 hasConceptScore W4200438766C2780596555 @default.
- W4200438766 hasConceptScore W4200438766C33923547 @default.
- W4200438766 hasConceptScore W4200438766C40993552 @default.
- W4200438766 hasConceptScore W4200438766C70410870 @default.
- W4200438766 hasConceptScore W4200438766C71924100 @default.
- W4200438766 hasFunder F4320307128 @default.
- W4200438766 hasFunder F4320309825 @default.
- W4200438766 hasFunder F4320310050 @default.
- W4200438766 hasFunder F4320310419 @default.
- W4200438766 hasFunder F4320312462 @default.
- W4200438766 hasFunder F4320337359 @default.
- W4200438766 hasIssue "5-6" @default.
- W4200438766 hasLocation W42004387661 @default.
- W4200438766 hasLocation W42004387662 @default.
- W4200438766 hasOpenAccess W4200438766 @default.
- W4200438766 hasPrimaryLocation W42004387661 @default.
- W4200438766 hasRelatedWork W1721695164 @default.
- W4200438766 hasRelatedWork W1790132802 @default.
- W4200438766 hasRelatedWork W2020201321 @default.
- W4200438766 hasRelatedWork W2087451326 @default.
- W4200438766 hasRelatedWork W2095364349 @default.
- W4200438766 hasRelatedWork W2898722641 @default.
- W4200438766 hasRelatedWork W3012131704 @default.
- W4200438766 hasRelatedWork W3193547925 @default.
- W4200438766 hasRelatedWork W338430866 @default.
- W4200438766 hasRelatedWork W4283458268 @default.
- W4200438766 hasVolume "23" @default.
- W4200438766 isParatext "false" @default.
- W4200438766 isRetracted "false" @default.
- W4200438766 workType "article" @default.