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- W4200445881 endingPage "13047" @default.
- W4200445881 startingPage "13047" @default.
- W4200445881 abstract "Increasing prevalence of metabolic syndrome (MetS) is causing a significant health burden among the European population. Current knowledge supports the notion that endocrine-disrupting chemicals (EDCs) interfere with human metabolism and hormonal balance, contributing to the conventionally recognized lifestyle-related MetS risk factors. This review aims to identify epidemiological studies focusing on the association between MetS or its individual components (e.g., obesity, insulin resistance, diabetes, dyslipidemia and hypertension) and eight HBM4EU priority substances (bisphenol A (BPA), per- and polyfluoroalkyl substances (PFASs), phthalates, polycyclic aromatic hydrocarbons (PAHs), pesticides and heavy metals (cadmium, arsenic and mercury)). Thus far, human biomonitoring (HBM) studies have presented evidence supporting the role of EDC exposures on the development of individual MetS components. The strength of the association varies between the components and EDCs. Current evidence on metabolic disturbances and EDCs is still limited and heterogeneous, and mainly represent studies from North America and Asia, highlighting the need for well-conducted and harmonized HBM programmes among the European population. Rigorous and ongoing HBM in combination with health monitoring can help to identify the most concerning EDC exposures, to guide future risk assessment and policy actions." @default.
- W4200445881 created "2021-12-31" @default.
- W4200445881 creator A5003853930 @default.
- W4200445881 creator A5024253124 @default.
- W4200445881 creator A5040279141 @default.
- W4200445881 creator A5084839127 @default.
- W4200445881 date "2021-12-10" @default.
- W4200445881 modified "2023-10-02" @default.
- W4200445881 title "Metabolic Syndrome and Endocrine Disrupting Chemicals: An Overview of Exposure and Health Effects" @default.
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