Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200458809> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4200458809 abstract "Cell-derived influenza vaccines are not subject to egg-adaptive mutations that have potential to decrease vaccine effectiveness. This retrospective analysis estimated the relative vaccine effectiveness (rVE) of cell-derived quadrivalent influenza vaccine (IIV4c) compared to standard egg-derived quadrivalent influenza vaccines (IIV4e) among recipients aged 4-64 years in the United States during the 2019-2020 influenza season.The IQVIA PharMetrics Plus administrative claims database was utilized. Study outcomes were assessed postvaccination through the end of the study period (7 March 2020). Inverse probability of treatment weighting (IPTW) was implemented to adjust for covariate imbalance. Adjusted rVE against influenza-related hospitalizations/emergency room (ER) visits and other clinical outcomes was estimated through IPTW-weighted Poisson regression models for the IIV4c and IIV4e cohorts and for the subgroup with ≥1 high-risk condition. Sensitivity analyses modifying the outcome assessment period as well as a doubly-robust analysis were also conducted. IPTW-weighted generalized linear models were used to estimate predicted annualized all-cause costs.The final sample comprised 1 150 134 IIV4c and 3 924 819 IIV4e recipients following IPTW adjustment. IIV4c was more effective in preventing influenza-related hospitalizations/ER visits as well as respiratory-related hospitalizations/ER visits compared to IIV4e. IIV4c was also more effective for the high-risk subgroup and across the sensitivity analyses. IIV4c was also associated with significantly lower annualized all-cause total costs compared to IIV4e (-$467), driven by lower costs for outpatient medical services and inpatient hospitalizations.IIV4c was significantly more effective in preventing influenza-related hospitalizations/ER visits compared to IIV4e and was associated with significantly lower all-cause costs." @default.
- W4200458809 created "2021-12-31" @default.
- W4200458809 creator A5011077808 @default.
- W4200458809 creator A5016565734 @default.
- W4200458809 creator A5029255725 @default.
- W4200458809 creator A5030519106 @default.
- W4200458809 creator A5051264386 @default.
- W4200458809 creator A5057426873 @default.
- W4200458809 creator A5065999728 @default.
- W4200458809 date "2021-12-04" @default.
- W4200458809 modified "2023-10-17" @default.
- W4200458809 title "A Real-World Clinical and Economic Analysis of Cell-Derived Quadrivalent Influenza Vaccine Compared to Standard Egg-Derived Quadrivalent Influenza Vaccines During the 2019–2020 Influenza Season in the United States" @default.
- W4200458809 cites W2110818436 @default.
- W4200458809 cites W2144387798 @default.
- W4200458809 cites W2765297310 @default.
- W4200458809 cites W2765398298 @default.
- W4200458809 cites W2767495920 @default.
- W4200458809 cites W2794531861 @default.
- W4200458809 cites W2899816568 @default.
- W4200458809 cites W2904354111 @default.
- W4200458809 cites W2904715936 @default.
- W4200458809 cites W2913781601 @default.
- W4200458809 cites W2979887792 @default.
- W4200458809 cites W3007443927 @default.
- W4200458809 cites W3008443627 @default.
- W4200458809 cites W3014346874 @default.
- W4200458809 cites W3029151080 @default.
- W4200458809 cites W3045976236 @default.
- W4200458809 cites W3046094430 @default.
- W4200458809 cites W3118346798 @default.
- W4200458809 cites W3125941622 @default.
- W4200458809 doi "https://doi.org/10.1093/ofid/ofab604" @default.
- W4200458809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35028334" @default.
- W4200458809 hasPublicationYear "2021" @default.
- W4200458809 type Work @default.
- W4200458809 citedByCount "10" @default.
- W4200458809 countsByYear W42004588092022 @default.
- W4200458809 countsByYear W42004588092023 @default.
- W4200458809 crossrefType "journal-article" @default.
- W4200458809 hasAuthorship W4200458809A5011077808 @default.
- W4200458809 hasAuthorship W4200458809A5016565734 @default.
- W4200458809 hasAuthorship W4200458809A5029255725 @default.
- W4200458809 hasAuthorship W4200458809A5030519106 @default.
- W4200458809 hasAuthorship W4200458809A5051264386 @default.
- W4200458809 hasAuthorship W4200458809A5057426873 @default.
- W4200458809 hasAuthorship W4200458809A5065999728 @default.
- W4200458809 hasBestOaLocation W42004588091 @default.
- W4200458809 hasConcept C126322002 @default.
- W4200458809 hasConcept C144024400 @default.
- W4200458809 hasConcept C149923435 @default.
- W4200458809 hasConcept C159047783 @default.
- W4200458809 hasConcept C187212893 @default.
- W4200458809 hasConcept C194828623 @default.
- W4200458809 hasConcept C22070199 @default.
- W4200458809 hasConcept C2780689484 @default.
- W4200458809 hasConcept C2908647359 @default.
- W4200458809 hasConcept C2911097425 @default.
- W4200458809 hasConcept C71924100 @default.
- W4200458809 hasConcept C73269764 @default.
- W4200458809 hasConcept C99454951 @default.
- W4200458809 hasConceptScore W4200458809C126322002 @default.
- W4200458809 hasConceptScore W4200458809C144024400 @default.
- W4200458809 hasConceptScore W4200458809C149923435 @default.
- W4200458809 hasConceptScore W4200458809C159047783 @default.
- W4200458809 hasConceptScore W4200458809C187212893 @default.
- W4200458809 hasConceptScore W4200458809C194828623 @default.
- W4200458809 hasConceptScore W4200458809C22070199 @default.
- W4200458809 hasConceptScore W4200458809C2780689484 @default.
- W4200458809 hasConceptScore W4200458809C2908647359 @default.
- W4200458809 hasConceptScore W4200458809C2911097425 @default.
- W4200458809 hasConceptScore W4200458809C71924100 @default.
- W4200458809 hasConceptScore W4200458809C73269764 @default.
- W4200458809 hasConceptScore W4200458809C99454951 @default.
- W4200458809 hasIssue "1" @default.
- W4200458809 hasLocation W42004588091 @default.
- W4200458809 hasLocation W42004588092 @default.
- W4200458809 hasLocation W42004588093 @default.
- W4200458809 hasLocation W42004588094 @default.
- W4200458809 hasLocation W42004588095 @default.
- W4200458809 hasOpenAccess W4200458809 @default.
- W4200458809 hasPrimaryLocation W42004588091 @default.
- W4200458809 hasRelatedWork W147953552 @default.
- W4200458809 hasRelatedWork W2287377033 @default.
- W4200458809 hasRelatedWork W2962970969 @default.
- W4200458809 hasRelatedWork W2971459369 @default.
- W4200458809 hasRelatedWork W3132683572 @default.
- W4200458809 hasRelatedWork W3136997019 @default.
- W4200458809 hasRelatedWork W4210822343 @default.
- W4200458809 hasRelatedWork W4299355133 @default.
- W4200458809 hasRelatedWork W4321601927 @default.
- W4200458809 hasRelatedWork W4367838377 @default.
- W4200458809 hasVolume "9" @default.
- W4200458809 isParatext "false" @default.
- W4200458809 isRetracted "false" @default.
- W4200458809 workType "article" @default.