Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200460864> ?p ?o ?g. }
- W4200460864 endingPage "504" @default.
- W4200460864 startingPage "495" @default.
- W4200460864 abstract "Schizophrenia is a chronic and disabling mental illness characterized by a disordered sense of self. Current theories suggest that deficiencies in the sense of control over one's actions (Sense of Agency, SoA) may underlie some of the symptoms of schizophrenia. However, it is not clear if agency deficits are a precursor or a result of psychosis. Here, we investigated full body agency using virtual reality in a cohort of 22q11 deletion syndrome participants with a genetic propensity for schizophrenia. In two experiments employing virtual reality, full body motion tracking, and online feedback, we investigated SoA in two separate domains. Our results show that participants with 22q11DS had a considerable deficit in monitoring their actions, compared to age-matched controls in both the temporal and spatial domain. This was coupled with a bias toward erroneous attribution of actions to the self. These results indicate that nonpsychotic 22q11DS participants have a domain general deficit in the conscious sensorimotor mechanisms underlying the bodily self. Our data reveal an abnormality in the SoA in a cohort with a genetic predisposition for schizophrenia, but without psychosis, providing evidence that deficits in delineation of the self may be a precursor rather than a result of the psychotic state." @default.
- W4200460864 created "2021-12-31" @default.
- W4200460864 creator A5030173881 @default.
- W4200460864 creator A5031829911 @default.
- W4200460864 creator A5035970779 @default.
- W4200460864 creator A5040553801 @default.
- W4200460864 creator A5048392298 @default.
- W4200460864 creator A5051118769 @default.
- W4200460864 creator A5075194192 @default.
- W4200460864 creator A5087845806 @default.
- W4200460864 date "2021-12-22" @default.
- W4200460864 modified "2023-10-05" @default.
- W4200460864 title "Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients" @default.
- W4200460864 cites W10567839 @default.
- W4200460864 cites W1567591130 @default.
- W4200460864 cites W1598485198 @default.
- W4200460864 cites W1951724000 @default.
- W4200460864 cites W1966777288 @default.
- W4200460864 cites W1968870951 @default.
- W4200460864 cites W1978830295 @default.
- W4200460864 cites W1979445479 @default.
- W4200460864 cites W198623452 @default.
- W4200460864 cites W1986907971 @default.
- W4200460864 cites W1989824314 @default.
- W4200460864 cites W1990043440 @default.
- W4200460864 cites W1992287533 @default.
- W4200460864 cites W1998707755 @default.
- W4200460864 cites W2006395252 @default.
- W4200460864 cites W2006473457 @default.
- W4200460864 cites W2009750010 @default.
- W4200460864 cites W2011841102 @default.
- W4200460864 cites W2014484736 @default.
- W4200460864 cites W2024062662 @default.
- W4200460864 cites W2032139276 @default.
- W4200460864 cites W2043253509 @default.
- W4200460864 cites W2054236226 @default.
- W4200460864 cites W2056666788 @default.
- W4200460864 cites W2067547952 @default.
- W4200460864 cites W2069979573 @default.
- W4200460864 cites W2070314367 @default.
- W4200460864 cites W2070461647 @default.
- W4200460864 cites W2071963488 @default.
- W4200460864 cites W2074917937 @default.
- W4200460864 cites W2075125455 @default.
- W4200460864 cites W2076462833 @default.
- W4200460864 cites W2089699258 @default.
- W4200460864 cites W2091093652 @default.
- W4200460864 cites W2096194883 @default.
- W4200460864 cites W2096356851 @default.
- W4200460864 cites W2097861969 @default.
- W4200460864 cites W2099916769 @default.
- W4200460864 cites W2104660409 @default.
- W4200460864 cites W2110023811 @default.
- W4200460864 cites W2114919588 @default.
- W4200460864 cites W2118777739 @default.
- W4200460864 cites W2122450331 @default.
- W4200460864 cites W2125964048 @default.
- W4200460864 cites W2129336069 @default.
- W4200460864 cites W2130309455 @default.
- W4200460864 cites W2134858962 @default.
- W4200460864 cites W2135722102 @default.
- W4200460864 cites W2135848692 @default.
- W4200460864 cites W2138985069 @default.
- W4200460864 cites W2141364268 @default.
- W4200460864 cites W2141451114 @default.
- W4200460864 cites W2146676564 @default.
- W4200460864 cites W2148307166 @default.
- W4200460864 cites W2150991704 @default.
- W4200460864 cites W2152092126 @default.
- W4200460864 cites W2153707159 @default.
- W4200460864 cites W2156691676 @default.
- W4200460864 cites W2158146863 @default.
- W4200460864 cites W2158370744 @default.
- W4200460864 cites W2162956002 @default.
- W4200460864 cites W2163725438 @default.
- W4200460864 cites W2167469007 @default.
- W4200460864 cites W2167701625 @default.
- W4200460864 cites W2168731009 @default.
- W4200460864 cites W2171381636 @default.
- W4200460864 cites W2531553530 @default.
- W4200460864 cites W2605067064 @default.
- W4200460864 cites W2753797053 @default.
- W4200460864 cites W2774486220 @default.
- W4200460864 cites W2798074670 @default.
- W4200460864 cites W2803735852 @default.
- W4200460864 cites W2905702364 @default.
- W4200460864 cites W2926352957 @default.
- W4200460864 cites W2995708135 @default.
- W4200460864 cites W3006223906 @default.
- W4200460864 cites W3049715998 @default.
- W4200460864 cites W3086993538 @default.
- W4200460864 cites W3090793875 @default.
- W4200460864 cites W3111760060 @default.
- W4200460864 cites W3137895442 @default.
- W4200460864 cites W3152071080 @default.
- W4200460864 cites W3156426893 @default.
- W4200460864 cites W3157808595 @default.
- W4200460864 cites W3190639431 @default.