Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200461750> ?p ?o ?g. }
- W4200461750 endingPage "121358" @default.
- W4200461750 startingPage "121358" @default.
- W4200461750 abstract "Ideal dressing materials for complex and large asymmetric burns should have the dual properties of anti-bacterial and regenerative with advanced applicability of direct deposit on the wound at the patient bedside. In this study, core-shell nanofibers (polycaprolactone; PCL and polyethylene oxide; PEO) with different percent of silver sulfadiazine (SSD) loading (2-10%) were prepared by the airbrushing method using a custom build device. Results indicate a sustained release profile of silver sulfadiazine (SSD) up to 28 days and concentration-dependent anti-bacterial activity. The morphology and proliferation of human dermal fibroblast (HDF) cells and human dental follicle stem cells (HDFSC) on the silver sulfadiazine loaded nanofibers confirm the biocompatibility of airbrushed nanofibers. Moreover, upregulation of extracellular matrix (ECM) proteins (Col I, Col III, and elastin) support the differentiation and regenerative properties of silver sulfadiazine nanofiber mats. This was further confirmed by the complete recovery of rabbit burn wound models within 7 days of silver sulfadiazine loaded nanofiber dressing. Histopathology data show silver sulfadiazine loaded core-shell nanofibers' anti-inflammatory and proliferative activity without any adverse response on the tissue. Overall data display that the airbrushed silver sulfadiazine-loaded core-shell nanofibers are effective dressing material with the possibility of direct fiber deposition on the wound to cover, heal, and regenerate large asymmetric burn wounds." @default.
- W4200461750 created "2021-12-31" @default.
- W4200461750 creator A5007629634 @default.
- W4200461750 creator A5009988412 @default.
- W4200461750 creator A5042661533 @default.
- W4200461750 creator A5049761968 @default.
- W4200461750 creator A5049855626 @default.
- W4200461750 creator A5066202330 @default.
- W4200461750 creator A5070350230 @default.
- W4200461750 creator A5085310698 @default.
- W4200461750 creator A5090924974 @default.
- W4200461750 date "2022-02-01" @default.
- W4200461750 modified "2023-10-15" @default.
- W4200461750 title "Silver sulfadiazine loaded core-shell airbrushed nanofibers for burn wound healing application" @default.
- W4200461750 cites W1791740470 @default.
- W4200461750 cites W1973422187 @default.
- W4200461750 cites W2004312602 @default.
- W4200461750 cites W2019444633 @default.
- W4200461750 cites W2033249991 @default.
- W4200461750 cites W2066735594 @default.
- W4200461750 cites W2077287304 @default.
- W4200461750 cites W2117808317 @default.
- W4200461750 cites W2118927867 @default.
- W4200461750 cites W2152773911 @default.
- W4200461750 cites W2331998009 @default.
- W4200461750 cites W2340361128 @default.
- W4200461750 cites W2507542036 @default.
- W4200461750 cites W2527738025 @default.
- W4200461750 cites W2589770862 @default.
- W4200461750 cites W2605309112 @default.
- W4200461750 cites W2622263840 @default.
- W4200461750 cites W2742167711 @default.
- W4200461750 cites W2774475547 @default.
- W4200461750 cites W2804431829 @default.
- W4200461750 cites W2837698172 @default.
- W4200461750 cites W2901417479 @default.
- W4200461750 cites W2908231263 @default.
- W4200461750 cites W2920428490 @default.
- W4200461750 cites W2922437909 @default.
- W4200461750 cites W2928332582 @default.
- W4200461750 cites W2929722587 @default.
- W4200461750 cites W2942415783 @default.
- W4200461750 cites W2947075584 @default.
- W4200461750 cites W2947094299 @default.
- W4200461750 cites W2962744446 @default.
- W4200461750 cites W2962763288 @default.
- W4200461750 cites W2968874011 @default.
- W4200461750 cites W2989485834 @default.
- W4200461750 cites W2991571923 @default.
- W4200461750 cites W3007523428 @default.
- W4200461750 cites W3012715695 @default.
- W4200461750 cites W3034658855 @default.
- W4200461750 cites W3036144060 @default.
- W4200461750 cites W3040105333 @default.
- W4200461750 cites W3043372307 @default.
- W4200461750 cites W3082954171 @default.
- W4200461750 cites W657006119 @default.
- W4200461750 doi "https://doi.org/10.1016/j.ijpharm.2021.121358" @default.
- W4200461750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34896560" @default.
- W4200461750 hasPublicationYear "2022" @default.
- W4200461750 type Work @default.
- W4200461750 citedByCount "8" @default.
- W4200461750 countsByYear W42004617502022 @default.
- W4200461750 countsByYear W42004617502023 @default.
- W4200461750 crossrefType "journal-article" @default.
- W4200461750 hasAuthorship W4200461750A5007629634 @default.
- W4200461750 hasAuthorship W4200461750A5009988412 @default.
- W4200461750 hasAuthorship W4200461750A5042661533 @default.
- W4200461750 hasAuthorship W4200461750A5049761968 @default.
- W4200461750 hasAuthorship W4200461750A5049855626 @default.
- W4200461750 hasAuthorship W4200461750A5066202330 @default.
- W4200461750 hasAuthorship W4200461750A5070350230 @default.
- W4200461750 hasAuthorship W4200461750A5085310698 @default.
- W4200461750 hasAuthorship W4200461750A5090924974 @default.
- W4200461750 hasConcept C127413603 @default.
- W4200461750 hasConcept C136229726 @default.
- W4200461750 hasConcept C141071460 @default.
- W4200461750 hasConcept C159985019 @default.
- W4200461750 hasConcept C185592680 @default.
- W4200461750 hasConcept C191897082 @default.
- W4200461750 hasConcept C192562407 @default.
- W4200461750 hasConcept C2776532303 @default.
- W4200461750 hasConcept C2777230088 @default.
- W4200461750 hasConcept C2778269047 @default.
- W4200461750 hasConcept C2779868350 @default.
- W4200461750 hasConcept C2780269544 @default.
- W4200461750 hasConcept C42360764 @default.
- W4200461750 hasConcept C501593827 @default.
- W4200461750 hasConcept C521977710 @default.
- W4200461750 hasConcept C55493867 @default.
- W4200461750 hasConcept C71924100 @default.
- W4200461750 hasConcept C91129048 @default.
- W4200461750 hasConceptScore W4200461750C127413603 @default.
- W4200461750 hasConceptScore W4200461750C136229726 @default.
- W4200461750 hasConceptScore W4200461750C141071460 @default.
- W4200461750 hasConceptScore W4200461750C159985019 @default.
- W4200461750 hasConceptScore W4200461750C185592680 @default.
- W4200461750 hasConceptScore W4200461750C191897082 @default.