FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200467852> ?p ?o ?g. }

• W4200467852 endingPage "1274" @default.
• W4200467852 startingPage "1262" @default.
• W4200467852 abstract "Abstract In the past decade, studies on the mammalian gut microbiome have revealed that different animal species have distinct gut microbial compositions. The functional ramifications of this variation in microbial composition remain unclear: do these taxonomic differences indicate microbial adaptations to host-specific functionality, or are these diverse microbial communities essentially functionally redundant, as has been indicated by previous metagenomics studies? Here, we examine the metabolic content of mammalian gut microbiomes as a direct window into ecosystem function, using an untargeted metabolomics platform to analyze 101 fecal samples from a range of 25 exotic mammalian species in collaboration with a zoological center. We find that mammalian metabolomes are chemically diverse and strongly linked to microbiome composition, and that metabolome composition is further correlated to the phylogeny of the mammalian host. Specific metabolites enriched in different animal species included modified and degraded host and dietary compounds such as bile acids and triterpenoids, as well as fermentation products such as lactate and short-chain fatty acids. Our results suggest that differences in microbial taxonomic composition are indeed translated to host-specific metabolism, indicating that taxonomically distant microbiomes are more functionally diverse than redundant." @default.
• W4200467852 created "2021-12-31" @default.
• W4200467852 creator A5017194182 @default.
• W4200467852 creator A5017209910 @default.
• W4200467852 creator A5028203074 @default.
• W4200467852 creator A5062285900 @default.
• W4200467852 creator A5067869927 @default.
• W4200467852 creator A5078518544 @default.
• W4200467852 creator A5082720301 @default.
• W4200467852 creator A5085526613 @default.
• W4200467852 creator A5088912364 @default.
• W4200467852 date "2021-12-13" @default.
• W4200467852 modified "2023-10-18" @default.
• W4200467852 title "Mammalian gut metabolomes mirror microbiome composition and host phylogeny" @default.
• W4200467852 cites W1480892354 @default.
• W4200467852 cites W1611854178 @default.
• W4200467852 cites W1840453322 @default.
• W4200467852 cites W1953702613 @default.
• W4200467852 cites W1973217994 @default.
• W4200467852 cites W1976474336 @default.
• W4200467852 cites W1985716651 @default.
• W4200467852 cites W1989299822 @default.
• W4200467852 cites W1990590570 @default.
• W4200467852 cites W2004592921 @default.
• W4200467852 cites W2006317824 @default.
• W4200467852 cites W2021266658 @default.
• W4200467852 cites W2023491827 @default.
• W4200467852 cites W2024330772 @default.
• W4200467852 cites W2027974246 @default.
• W4200467852 cites W2028596084 @default.
• W4200467852 cites W2034285706 @default.
• W4200467852 cites W2040547956 @default.
• W4200467852 cites W2049506766 @default.
• W4200467852 cites W2053310956 @default.
• W4200467852 cites W2056279562 @default.
• W4200467852 cites W2064490992 @default.
• W4200467852 cites W2071273298 @default.
• W4200467852 cites W2073475802 @default.
• W4200467852 cites W2081465448 @default.
• W4200467852 cites W2083212229 @default.
• W4200467852 cites W2087580548 @default.
• W4200467852 cites W20889061 @default.
• W4200467852 cites W2091910674 @default.
• W4200467852 cites W2109018631 @default.
• W4200467852 cites W2112874908 @default.
• W4200467852 cites W2115438056 @default.
• W4200467852 cites W2117029130 @default.
• W4200467852 cites W2120398282 @default.
• W4200467852 cites W2122914905 @default.
• W4200467852 cites W2127059753 @default.
• W4200467852 cites W2128769815 @default.
• W4200467852 cites W2137111266 @default.
• W4200467852 cites W2138559236 @default.
• W4200467852 cites W2139129413 @default.
• W4200467852 cites W2139907115 @default.
• W4200467852 cites W2144568881 @default.
• W4200467852 cites W2149573313 @default.
• W4200467852 cites W2153452535 @default.
• W4200467852 cites W2159482845 @default.
• W4200467852 cites W2162904770 @default.
• W4200467852 cites W2163250554 @default.
• W4200467852 cites W2166171121 @default.
• W4200467852 cites W2257201151 @default.
• W4200467852 cites W2297247152 @default.
• W4200467852 cites W2312022769 @default.
• W4200467852 cites W2337896384 @default.
• W4200467852 cites W2345991090 @default.
• W4200467852 cites W2401404581 @default.
• W4200467852 cites W2477618789 @default.
• W4200467852 cites W2504233374 @default.
• W4200467852 cites W2504691963 @default.
• W4200467852 cites W2520355709 @default.
• W4200467852 cites W2548357532 @default.
• W4200467852 cites W2550084345 @default.
• W4200467852 cites W2553365624 @default.
• W4200467852 cites W2589580339 @default.
• W4200467852 cites W2604308930 @default.
• W4200467852 cites W2666871553 @default.
• W4200467852 cites W2743115441 @default.
• W4200467852 cites W2767046664 @default.
• W4200467852 cites W2776194694 @default.
• W4200467852 cites W2778026792 @default.
• W4200467852 cites W2797101767 @default.
• W4200467852 cites W2800712778 @default.
• W4200467852 cites W2803475077 @default.
• W4200467852 cites W2805711297 @default.
• W4200467852 cites W2806494097 @default.
• W4200467852 cites W2844764223 @default.
• W4200467852 cites W2883251903 @default.
• W4200467852 cites W2884158320 @default.
• W4200467852 cites W2890638703 @default.
• W4200467852 cites W2917494464 @default.
• W4200467852 cites W2951517287 @default.
• W4200467852 cites W2956419562 @default.
• W4200467852 cites W2964962118 @default.
• W4200467852 cites W2979675761 @default.
• W4200467852 cites W2987666536 @default.
• W4200467852 cites W2988490574 @default.

• next