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- W4200468276 abstract "This study investigated the influence of whole body cooling on local thermal sensitivity to warm (40°C) and cold (20°C) stimuli in 10 young (age: 24 ± 2 yrs) and 10 older males (age: 69 ± 4 yrs).Local warm and cold sensitivity was assessed at eight body regions using a 25 cm2 pressure controlled thermal probe after 40 min of whole body exposure to a thermoneutral (NEUT: 25°C/40% RH) and a cold (COLD: 12°C/50% RH) environment. Gastrointestinal temperature (Tgi), mean and local skin temperature, heart rate, whole body thermal sensation and comfort, and skin blood flow were also measured.Whole body cooling blunted local cold sensitivity but warm sensitivity was maintained in both age groups. Furthermore, a significant age-related decline (from young to older group) in sensitivity to a warm stimulus was observed in both NEUT and COLD conditions. Older males also had a greater ΔTgi compared to the young but had similar thermal sensation and comfort responses.The observed interaction effect of local cold stimulation and whole body cooling may be related to both stimuli triggering similar TRP channels, whereas the lack of interaction between local warm stimuli and whole body cooling may be related to these two stimuli triggering different TRP channels. The findings reiterate the potential thermoregulatory risks (e.g. cold injury and hypothermia) associated with ageing, even with such short exposure times." @default.
- W4200468276 created "2021-12-31" @default.
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- W4200468276 date "2022-02-01" @default.
- W4200468276 modified "2023-10-02" @default.
- W4200468276 title "Age comparison of changes in local warm and cold sensitivity due to whole body cooling" @default.
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- W4200468276 doi "https://doi.org/10.1016/j.jtherbio.2021.103174" @default.
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