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• W4200478635 endingPage "16525" @default.
• W4200478635 startingPage "16515" @default.
• W4200478635 abstract "Excess dietary seleno-l-methionine (Se-Met) induces various adverse effects in fish inhabiting the Se-contaminated environments. However, there is an extreme paucity of data on the effects of excess dietary Se-Met on the microbiota in the gastrointestinal (GI) tract in fish. In this study, Japanese medaka Oryzias latipes (three months old) were fed the Se-Met enriched diets at environmentally relevant concentrations: 2.90 (Control: (C), 6.69 (L), 11.89 (M), and 27.05 (H) μg Se/g dw) for 60 d. Histopathological, high throughput sequencing, and biochemical approaches were used to investigate the alterations in histology and microbial communities of the GI tract, enzymatic activity, and transcripts of closely related genes. The results showed that the fish weight was reduced at ∼13% from the L and H treatments. Decreased height and thickness of villus in the GI tract were observed in the H treatment. Meanwhile, the level of D-lactate and activity of diamine oxidase (DAO), protease, and lipase were inhibited in the H treatment. The transcripts of the genes related to the inflammation (i.e., IL-1β and IL-8) were elevated, while those of the genes related to the intestinal barrier (i.e., cdh1, ZO-1, ocln, and cldn7) were inhibited in the H treatment. In addition, alpha diversity at the genus level was higher in the L treatment than the control, and the composition of the microbial community was altered by dietary Se-Met. Furthermore, 5 genera (Rhodobacter, Cloacibacterium, Bdellovibrio, Shinella, and Aeromonas) exhibited the largest variation in abundance among treatments. This study has demonstrated that excess dietary Se-Met inhibits growth, causes hispathological damage to the GI tract, and alters the composition of the microbial community in Oryzias latipes." @default.
• W4200478635 created "2021-12-31" @default.
• W4200478635 creator A5032342559 @default.
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• W4200478635 date "2021-12-07" @default.
• W4200478635 modified "2023-10-03" @default.
• W4200478635 title "Dietary Seleno-<scp>l</scp>-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka <i>Oryzias latipes</i>" @default.
• W4200478635 cites W1503669377 @default.
• W4200478635 cites W1561920413 @default.
• W4200478635 cites W1606088617 @default.
• W4200478635 cites W1963670169 @default.
• W4200478635 cites W1968739283 @default.
• W4200478635 cites W1969612218 @default.
• W4200478635 cites W1969984380 @default.
• W4200478635 cites W1978469056 @default.
• W4200478635 cites W1992152055 @default.
• W4200478635 cites W1996648940 @default.
• W4200478635 cites W1997039338 @default.
• W4200478635 cites W1997892998 @default.
• W4200478635 cites W2006275267 @default.
• W4200478635 cites W2010726876 @default.
• W4200478635 cites W2020146381 @default.
• W4200478635 cites W2021469461 @default.
• W4200478635 cites W2027077137 @default.
• W4200478635 cites W2028789107 @default.
• W4200478635 cites W2029314137 @default.
• W4200478635 cites W2029598860 @default.
• W4200478635 cites W2030009677 @default.
• W4200478635 cites W2042045767 @default.
• W4200478635 cites W2043651027 @default.
• W4200478635 cites W2043731532 @default.
• W4200478635 cites W2045782178 @default.
• W4200478635 cites W2048244789 @default.
• W4200478635 cites W2053332821 @default.
• W4200478635 cites W2054460269 @default.
• W4200478635 cites W2055793601 @default.
• W4200478635 cites W2059235491 @default.
• W4200478635 cites W2062658141 @default.
• W4200478635 cites W2075863546 @default.
• W4200478635 cites W2079669753 @default.
• W4200478635 cites W2093930599 @default.
• W4200478635 cites W2093962372 @default.
• W4200478635 cites W2102090879 @default.
• W4200478635 cites W2110235509 @default.
• W4200478635 cites W2130440900 @default.
• W4200478635 cites W2137522518 @default.
• W4200478635 cites W2143531675 @default.
• W4200478635 cites W2146316143 @default.
• W4200478635 cites W2158421682 @default.
• W4200478635 cites W2167454999 @default.
• W4200478635 cites W2329345240 @default.
• W4200478635 cites W2345411160 @default.
• W4200478635 cites W2396185588 @default.
• W4200478635 cites W2409366127 @default.
• W4200478635 cites W2467881715 @default.
• W4200478635 cites W2480662323 @default.
• W4200478635 cites W2482000845 @default.
• W4200478635 cites W2518276548 @default.
• W4200478635 cites W2605052214 @default.
• W4200478635 cites W2736401245 @default.
• W4200478635 cites W2763621344 @default.
• W4200478635 cites W2782266673 @default.
• W4200478635 cites W2805028939 @default.
• W4200478635 cites W2807194798 @default.
• W4200478635 cites W2892077925 @default.
• W4200478635 cites W2903235790 @default.
• W4200478635 cites W2914833654 @default.
• W4200478635 cites W2942995341 @default.
• W4200478635 cites W2960871149 @default.
• W4200478635 cites W2963276645 @default.
• W4200478635 cites W2969391308 @default.
• W4200478635 cites W2978047156 @default.
• W4200478635 cites W2981954579 @default.
• W4200478635 cites W2990766130 @default.
• W4200478635 cites W2996302775 @default.
• W4200478635 cites W3010800906 @default.
• W4200478635 cites W3041120289 @default.
• W4200478635 cites W3046338675 @default.
• W4200478635 cites W3084214197 @default.
• W4200478635 cites W3088114376 @default.
• W4200478635 cites W3092928132 @default.
• W4200478635 cites W3093219257 @default.
• W4200478635 cites W3128162554 @default.
• W4200478635 cites W3130938010 @default.
• W4200478635 cites W3137795654 @default.
• W4200478635 cites W3193960725 @default.
• W4200478635 cites W4255800959 @default.
• W4200478635 doi "https://doi.org/10.1021/acs.est.1c04533" @default.
• W4200478635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34874707" @default.
• W4200478635 hasPublicationYear "2021" @default.
• W4200478635 type Work @default.

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