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• W4200480587 abstract "The COVID-19 pandemic is the most significant current public health crisis.We conducted a retrospective case series, including patients under 18 years of age admitted to respiratory triage and hospitalized with COVID-19 infection in two hospital centers. Epidemiological, clinical, laboratory and radiological findings were documented. The diagnosis of COVID-19 was confirmed by real-time reverse transcription-polymerase chain reaction (RT-PCR). For the analysis, patients were classified into three groups: no comorbidities, immunocompromised, and with chronic disease.Fifty-four patients with COVID-19 were identified: 40 (74.1%) were admitted through respiratory triage. Of these, 28 (70%) were hospitalized, and 14 (25.9%) were already in the hospital. In addition, 26 (48.1%) presented comorbidities. A mild clinical course was observed in 14 cases (53.7%). The mean age was 6 years, with an interquartile range from 11 months to 13 years. The male sex was more frequent, representing 59.3%. Fever was the most common symptom in 74% of the patients. Lymphopenia was observed in 28.6%, and 69.3% had elevated C-reactive protein. Ground glass injuries were documented in 30.9% of COVID-19 cases; 11.1% of the patients required mechanical ventilation and vasopressor treatment.Fever was the main symptom, and mild infection was the principal presentation. In hospitalized patients with some comorbidity and COVID-19, the disease was more severe, with a high percentage of mortality.La pandemia de COVID-19 es la mayor crisis de salud pública actual.Análisis de una serie de casos retrospectiva de pacientes menores de 18 años que ingresaron al triaje respiratorio y de pacientes hospitalizados con COVID-19 en dos centros hospitalarios. Se registraron variables epidemiológicas, clínicas, de laboratorio y radiológicas. El diagnóstico de COVID-19 fue confirmado por reacción en cadena de la polimerasa con transcriptasa inversa en tiempo real (RT-PCR). Para el análisis, los pacientes se clasificaron en tres grupos: sin comorbilidad, inmunocomprometidos y con enfermedad crónica.Se identificaron 54 pacientes con COVID-19, de los cuales 40 (74.1%) ingresaron por el triaje respiratorio y, de estos, 28 (70%) fueron hospitalizados y 14 (25.9%) ya estaban hospitalizados; 26 pacientes (48.1%) presentaban comorbilidad. El curso clínico leve se observó con mayor frecuencia, en 14 casos (53.7%). La mediana de edad fue de 6 años (rango intercuartílico: 11 meses a 13 años). El sexo masculino fue más frecuente, con el 59.3%. La fiebre fue el síntoma más común, en el 74% de los pacientes. Se observó linfocitopenia en el 28.6%, y el 69.3% presentaron elevación de la proteína C reactiva. Las lesiones en vidrio esmerilado se documentaron en el 30.9% de los casos y el 11.1% de los pacientes requirieron ventilación mecánica y tratamiento vasopresor.La fiebre fue el síntoma principal y la presentación leve de la enfermedad fue la más frecuente. En los pacientes hospitalizados con alguna comorbilidad e infectados por COVID-19, la gravedad de la enfermedad fue mayor, con un alto porcentaje de mortalidad." @default.
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• W4200480587 date "2021-12-20" @default.
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• W4200480587 title "Clinical and epidemiological characteristics of COVID-19 in children: experience in two hospitals" @default.
• W4200480587 doi "https://doi.org/10.24875/bmhim.20000250" @default.
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