Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200501183> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4200501183 abstract "Abstract Background Pancreatic adenocarcinoma (PDAC) is one of the most lethal tumours with a five-year survival rate of less than 7% for all stages. However, current evidence suggests neoadjuvant treatment (NAT) may have survival benefits in those with borderline resectable disease. Post-operative pancreatic fistula (POPF) is a potential complication after pancreaticoduodenectomy (PD) and is associated with long-term morbidity. The rate of developing POPF post-PD in those receiving NAT is currently unclear. Methods Patients undergoing PD (both classical and pylorus-preserving) were identified from a prospectively collected local database. Those who received NAT prior to surgery were identified, and case-matched controls based on their age and sex, were then identified from the database. Post-operative drain amylase levels were used to compare POPF between groups. For the analysis, drain amylase levels greater than three times the upper limit of normal at day five were consistent with biochemical POPF. Results A total of 34 patients (14 females, 20 males) underwent PD after receiving NAT at our unit from January 2013 to July 2021. The median age was 66 years at the time of surgery. Two patients (5.9%) in the NAC group had biochemical leaks on day five compared to 4 (11.8%) in the case-matched control group (p = 0.7). Conclusions Our early data suggest a possibility of a lower incidence of biochemical POPF in those undergoing PD post-NAT. Aetiology on the development of POPD post-NAT is still unclear, and this requires further study and long-term follow up." @default.
- W4200501183 created "2021-12-31" @default.
- W4200501183 creator A5004104224 @default.
- W4200501183 creator A5007992268 @default.
- W4200501183 creator A5010780371 @default.
- W4200501183 creator A5015927502 @default.
- W4200501183 creator A5028912750 @default.
- W4200501183 creator A5042451343 @default.
- W4200501183 creator A5044836213 @default.
- W4200501183 creator A5058757810 @default.
- W4200501183 creator A5070495773 @default.
- W4200501183 creator A5086010363 @default.
- W4200501183 date "2021-12-01" @default.
- W4200501183 modified "2023-10-17" @default.
- W4200501183 title "P-P47 Impact of neoadjuvant chemotherapy on postoperative pancreatic fistula in patients undergoing pancreaticoduodenectomy" @default.
- W4200501183 doi "https://doi.org/10.1093/bjs/znab430.269" @default.
- W4200501183 hasPublicationYear "2021" @default.
- W4200501183 type Work @default.
- W4200501183 citedByCount "0" @default.
- W4200501183 crossrefType "journal-article" @default.
- W4200501183 hasAuthorship W4200501183A5004104224 @default.
- W4200501183 hasAuthorship W4200501183A5007992268 @default.
- W4200501183 hasAuthorship W4200501183A5010780371 @default.
- W4200501183 hasAuthorship W4200501183A5015927502 @default.
- W4200501183 hasAuthorship W4200501183A5028912750 @default.
- W4200501183 hasAuthorship W4200501183A5042451343 @default.
- W4200501183 hasAuthorship W4200501183A5044836213 @default.
- W4200501183 hasAuthorship W4200501183A5058757810 @default.
- W4200501183 hasAuthorship W4200501183A5070495773 @default.
- W4200501183 hasAuthorship W4200501183A5086010363 @default.
- W4200501183 hasBestOaLocation W42005011831 @default.
- W4200501183 hasConcept C120665830 @default.
- W4200501183 hasConcept C121332964 @default.
- W4200501183 hasConcept C121608353 @default.
- W4200501183 hasConcept C126322002 @default.
- W4200501183 hasConcept C141071460 @default.
- W4200501183 hasConcept C159110652 @default.
- W4200501183 hasConcept C2776694085 @default.
- W4200501183 hasConcept C2778292576 @default.
- W4200501183 hasConcept C2778764654 @default.
- W4200501183 hasConcept C2778975757 @default.
- W4200501183 hasConcept C2780911694 @default.
- W4200501183 hasConcept C2781182431 @default.
- W4200501183 hasConcept C530470458 @default.
- W4200501183 hasConcept C61511704 @default.
- W4200501183 hasConcept C71924100 @default.
- W4200501183 hasConcept C81182388 @default.
- W4200501183 hasConcept C90924648 @default.
- W4200501183 hasConceptScore W4200501183C120665830 @default.
- W4200501183 hasConceptScore W4200501183C121332964 @default.
- W4200501183 hasConceptScore W4200501183C121608353 @default.
- W4200501183 hasConceptScore W4200501183C126322002 @default.
- W4200501183 hasConceptScore W4200501183C141071460 @default.
- W4200501183 hasConceptScore W4200501183C159110652 @default.
- W4200501183 hasConceptScore W4200501183C2776694085 @default.
- W4200501183 hasConceptScore W4200501183C2778292576 @default.
- W4200501183 hasConceptScore W4200501183C2778764654 @default.
- W4200501183 hasConceptScore W4200501183C2778975757 @default.
- W4200501183 hasConceptScore W4200501183C2780911694 @default.
- W4200501183 hasConceptScore W4200501183C2781182431 @default.
- W4200501183 hasConceptScore W4200501183C530470458 @default.
- W4200501183 hasConceptScore W4200501183C61511704 @default.
- W4200501183 hasConceptScore W4200501183C71924100 @default.
- W4200501183 hasConceptScore W4200501183C81182388 @default.
- W4200501183 hasConceptScore W4200501183C90924648 @default.
- W4200501183 hasIssue "Supplement_9" @default.
- W4200501183 hasLocation W42005011831 @default.
- W4200501183 hasOpenAccess W4200501183 @default.
- W4200501183 hasPrimaryLocation W42005011831 @default.
- W4200501183 hasRelatedWork W2010762426 @default.
- W4200501183 hasRelatedWork W2066147875 @default.
- W4200501183 hasRelatedWork W2157448707 @default.
- W4200501183 hasRelatedWork W2350884673 @default.
- W4200501183 hasRelatedWork W2417961914 @default.
- W4200501183 hasRelatedWork W2474039552 @default.
- W4200501183 hasRelatedWork W2895207514 @default.
- W4200501183 hasRelatedWork W2945124548 @default.
- W4200501183 hasRelatedWork W3091620187 @default.
- W4200501183 hasRelatedWork W62711790 @default.
- W4200501183 hasVolume "108" @default.
- W4200501183 isParatext "false" @default.
- W4200501183 isRetracted "false" @default.
- W4200501183 workType "article" @default.