FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200501192> ?p ?o ?g. }

• W4200501192 endingPage "339350" @default.
• W4200501192 startingPage "339350" @default.
• W4200501192 abstract "Point of care (POC), also identified as on-site testing, has evolved as a rapid and accurate technique for drug of abuse screening and analysis. The aim of this work is to detect tropicamide (TPC) abuse in biological fluids; we selected rat plasma as example. We developed a disposal miniaturized, portable, green, and budget-friendly POC solid-state electrochemical sensor based on potentiometric transduction. To attain that, an innovative microfabricated electrode modified with conducting polymer poly(3-octylthiophene) (POT) has been placed on sensitized printed circuit board (PCB). A two-stage optimization process was implemented to develop the fabricated electrode. The first stage of the optimization process depends on screening various ionophores in order to enhance the sensor selectivity towards tropicamide. Copper nanoparticles exhibited the highest selectivity towards TPC. The second stage was utilizing a polymer as an ion-to-electron transducer layer between the copper nanoparticles impregnated ion sensing membrane and the microfabricated solid-contact ion-selective electrode. This polymer was added to boost the stability of the potential drift (1.2 mV/h) due to the hydrophobic behavior of the POT, which precludes the formation of an aqueous layer at the Cu electrode/polymeric membrane interface and improve the limit of detection (1.1 × 10-8 M). Nernstian potentiometric response was accomplished for TPC with a slope of 58.46 ± 0.43 mV/decade and E0 ∼ 189.39 ± 2.12 over the concentration range 1.0 × 10-7 to 1.0 × 10-2 M. The suggested sensor's intrinsic figure of merits include a quick response time (13 ± 2 s) and long life time (45 days). The proposed sensor has been successfully employed in the selective determination of TPC in pharmaceutical formulations, and biological fluids. When the results were compared to those of the official approach, there was no statistically significant difference. The Eco-Scale tool assessed and measured the greenness profile of the established method." @default.
• W4200501192 created "2021-12-31" @default.
• W4200501192 creator A5029193461 @default.
• W4200501192 creator A5029733893 @default.
• W4200501192 creator A5041728291 @default.
• W4200501192 creator A5062368567 @default.
• W4200501192 creator A5062378622 @default.
• W4200501192 creator A5073807774 @default.
• W4200501192 date "2022-02-01" @default.
• W4200501192 modified "2023-09-26" @default.
• W4200501192 title "Nanoparticle-enhanced in-line potentiometric ion sensor for point-of-care diagnostics for tropicamide abuse in biological fluid" @default.
• W4200501192 cites W1978415620 @default.
• W4200501192 cites W1996842820 @default.
• W4200501192 cites W2004671837 @default.
• W4200501192 cites W2009907824 @default.
• W4200501192 cites W2027328166 @default.
• W4200501192 cites W2037181348 @default.
• W4200501192 cites W2037447236 @default.
• W4200501192 cites W2040526752 @default.
• W4200501192 cites W2051004637 @default.
• W4200501192 cites W2056394951 @default.
• W4200501192 cites W2063357296 @default.
• W4200501192 cites W2075489519 @default.
• W4200501192 cites W2075997494 @default.
• W4200501192 cites W2079109852 @default.
• W4200501192 cites W2082405251 @default.
• W4200501192 cites W2087547279 @default.
• W4200501192 cites W2147768883 @default.
• W4200501192 cites W2273582519 @default.
• W4200501192 cites W2313505840 @default.
• W4200501192 cites W2341083424 @default.
• W4200501192 cites W2566675395 @default.
• W4200501192 cites W2613448788 @default.
• W4200501192 cites W2774886854 @default.
• W4200501192 cites W2909174108 @default.
• W4200501192 cites W2910284181 @default.
• W4200501192 cites W2975399231 @default.
• W4200501192 cites W2985676105 @default.
• W4200501192 cites W2996397914 @default.
• W4200501192 cites W3008502457 @default.
• W4200501192 cites W3047639126 @default.
• W4200501192 cites W3080905231 @default.
• W4200501192 cites W3088671577 @default.
• W4200501192 cites W3091690150 @default.
• W4200501192 cites W3132672796 @default.
• W4200501192 doi "https://doi.org/10.1016/j.aca.2021.339350" @default.
• W4200501192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35057968" @default.
• W4200501192 hasPublicationYear "2022" @default.
• W4200501192 type Work @default.
• W4200501192 citedByCount "5" @default.
• W4200501192 countsByYear W42005011922022 @default.
• W4200501192 countsByYear W42005011922023 @default.
• W4200501192 crossrefType "journal-article" @default.
• W4200501192 hasAuthorship W4200501192A5029193461 @default.
• W4200501192 hasAuthorship W4200501192A5029733893 @default.
• W4200501192 hasAuthorship W4200501192A5041728291 @default.
• W4200501192 hasAuthorship W4200501192A5062368567 @default.
• W4200501192 hasAuthorship W4200501192A5062378622 @default.
• W4200501192 hasAuthorship W4200501192A5073807774 @default.
• W4200501192 hasConcept C113196181 @default.
• W4200501192 hasConcept C119128265 @default.
• W4200501192 hasConcept C124614425 @default.
• W4200501192 hasConcept C127413603 @default.
• W4200501192 hasConcept C147789679 @default.
• W4200501192 hasConcept C155672457 @default.
• W4200501192 hasConcept C171250308 @default.
• W4200501192 hasConcept C17525397 @default.
• W4200501192 hasConcept C185592680 @default.
• W4200501192 hasConcept C192562407 @default.
• W4200501192 hasConcept C195767000 @default.
• W4200501192 hasConcept C40290423 @default.
• W4200501192 hasConcept C41625074 @default.
• W4200501192 hasConcept C42360764 @default.
• W4200501192 hasConcept C43617362 @default.
• W4200501192 hasConcept C52859227 @default.
• W4200501192 hasConcept C55493867 @default.
• W4200501192 hasConceptScore W4200501192C113196181 @default.
• W4200501192 hasConceptScore W4200501192C119128265 @default.
• W4200501192 hasConceptScore W4200501192C124614425 @default.
• W4200501192 hasConceptScore W4200501192C127413603 @default.
• W4200501192 hasConceptScore W4200501192C147789679 @default.
• W4200501192 hasConceptScore W4200501192C155672457 @default.
• W4200501192 hasConceptScore W4200501192C171250308 @default.
• W4200501192 hasConceptScore W4200501192C17525397 @default.
• W4200501192 hasConceptScore W4200501192C185592680 @default.
• W4200501192 hasConceptScore W4200501192C192562407 @default.
• W4200501192 hasConceptScore W4200501192C195767000 @default.
• W4200501192 hasConceptScore W4200501192C40290423 @default.
• W4200501192 hasConceptScore W4200501192C41625074 @default.
• W4200501192 hasConceptScore W4200501192C42360764 @default.
• W4200501192 hasConceptScore W4200501192C43617362 @default.
• W4200501192 hasConceptScore W4200501192C52859227 @default.
• W4200501192 hasConceptScore W4200501192C55493867 @default.
• W4200501192 hasLocation W42005011921 @default.
• W4200501192 hasLocation W42005011922 @default.
• W4200501192 hasOpenAccess W4200501192 @default.
• W4200501192 hasPrimaryLocation W42005011921 @default.
• W4200501192 hasRelatedWork W1590691788 @default.

• next