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- W4200503276 abstract "Moyamoya disease is an unusual form of chronic cerebrovascular occlusive disease that is characterized by angiographic findings of bilateral stenosis or occlusion at the terminal portion of the internal carotid artery together with an abnormal vascular network at the base of the brain. Clinical symptoms and signs are the manifestations of cerebrovascular events secondary to the intracranial vascular lesions, including hemorrhagic stroke, ischemic stroke, transient ischemic attacks (TIAs) and seizure. Ischemic events are common in childhood, whereas hemorrhagic strokes are frequently seen in adulthood. Incidence is high in Japan and in east Asia. The female-to-male ratio is 1.8:1. Although genetic linkage analysis demonstrated that hereditary factors may be involved in susceptibility to moyamoya disease, etiology has not been fully elucidated yet. Ischemic and hemorrhagic lesions and major arteries are evaluated by CT, MRI, angiography, MR angiography (MRA), and carotid ultrasonography. Antiplatelet agents are prescribed to prevent recurrent ischemic attacks, although they have never been tested thoroughly in clinical trials. Surgical revascularization including direct bypass surgery, indirect bypass surgery, and a combination of the two has been performed to give additional collateral flow to the ischemic brain. A recent multicenter randomized controlled study supported preventative effect of direct bypass against rebleeding in adult-onset hemorrhagic moyamoya disease." @default.
- W4200503276 created "2021-12-31" @default.
- W4200503276 creator A5015689408 @default.
- W4200503276 creator A5031958800 @default.
- W4200503276 creator A5041888985 @default.
- W4200503276 date "2022-01-01" @default.
- W4200503276 modified "2023-09-25" @default.
- W4200503276 title "Moyamoya Disease" @default.
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