FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200504429> ?p ?o ?g. }

• W4200504429 endingPage "456" @default.
• W4200504429 startingPage "451" @default.
• W4200504429 abstract "Kynurenic acid (KYNA) is a metabolite of tryptophan (TRP). KYNA levels have been reported with controversial findings in patients with schizophrenia.This study aimed to investigate the probable effects of medication and illness chronicity on peripheral KYNA levels in schizophrenia.We assessed peripheral (plasma) TRP metabolite levels in 38 drug-free patients with first-episode schizophrenia (FES), 65 patients with chronic schizophrenia (CHS), and 70 healthy controls by using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). The symptom severity of patients was evaluated by using the Positive and Negative Syndrome Scale (PANSS). Finally, we analyzed the association of TRP metabolites with symptom severity.We found significantly higher KYNA levels in FES patients than in both healthy controls (p < 0.01) and CHS patients (p < 0.05). No significant association was observed between plasma TRP metabolite levels and PANSS scores in either FES or CHS patients.In conclusion, elevated plasma KYNA levels may be a promising biomarker in FES patients. Medication and illness chronicity may affect peripheral KYNA levels with a currently unknown mechanism." @default.
• W4200504429 created "2021-12-31" @default.
• W4200504429 creator A5005078210 @default.
• W4200504429 creator A5018837129 @default.
• W4200504429 creator A5025285333 @default.
• W4200504429 creator A5035411450 @default.
• W4200504429 creator A5043336955 @default.
• W4200504429 creator A5083194041 @default.
• W4200504429 date "2021-12-20" @default.
• W4200504429 modified "2023-09-25" @default.
• W4200504429 title "Increased plasma level of kynurenic acid in drug-free patients with first-episode schizophrenia compared to patients with chronic schizophrenia and healthy controls: preliminary data" @default.
• W4200504429 cites W1547937746 @default.
• W4200504429 cites W1896173558 @default.
• W4200504429 cites W1996580716 @default.
• W4200504429 cites W2014887893 @default.
• W4200504429 cites W2023083861 @default.
• W4200504429 cites W2039232652 @default.
• W4200504429 cites W2049985274 @default.
• W4200504429 cites W2072058525 @default.
• W4200504429 cites W2081803015 @default.
• W4200504429 cites W2084911947 @default.
• W4200504429 cites W2118643787 @default.
• W4200504429 cites W2126308470 @default.
• W4200504429 cites W2131932927 @default.
• W4200504429 cites W2137823415 @default.
• W4200504429 cites W2139194458 @default.
• W4200504429 cites W2150265247 @default.
• W4200504429 cites W2260534687 @default.
• W4200504429 cites W2586728661 @default.
• W4200504429 cites W2591858183 @default.
• W4200504429 cites W2713444075 @default.
• W4200504429 cites W2768536557 @default.
• W4200504429 cites W2789527934 @default.
• W4200504429 cites W2805153744 @default.
• W4200504429 cites W2929017669 @default.
• W4200504429 cites W2966694204 @default.
• W4200504429 cites W2999592151 @default.
• W4200504429 cites W3002957766 @default.
• W4200504429 cites W3004861503 @default.
• W4200504429 cites W3011570543 @default.
• W4200504429 cites W3132061645 @default.
• W4200504429 cites W3142125382 @default.
• W4200504429 cites W3160628035 @default.
• W4200504429 cites W3163033365 @default.
• W4200504429 cites W4229548235 @default.
• W4200504429 cites W618617582 @default.
• W4200504429 doi "https://doi.org/10.1080/08039488.2021.1992647" @default.
• W4200504429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34928781" @default.
• W4200504429 hasPublicationYear "2021" @default.
• W4200504429 type Work @default.
• W4200504429 citedByCount "1" @default.
• W4200504429 countsByYear W42005044292023 @default.
• W4200504429 crossrefType "journal-article" @default.
• W4200504429 hasAuthorship W4200504429A5005078210 @default.
• W4200504429 hasAuthorship W4200504429A5018837129 @default.
• W4200504429 hasAuthorship W4200504429A5025285333 @default.
• W4200504429 hasAuthorship W4200504429A5035411450 @default.
• W4200504429 hasAuthorship W4200504429A5043336955 @default.
• W4200504429 hasAuthorship W4200504429A5083194041 @default.
• W4200504429 hasConcept C118552586 @default.
• W4200504429 hasConcept C126322002 @default.
• W4200504429 hasConcept C170493617 @default.
• W4200504429 hasConcept C185592680 @default.
• W4200504429 hasConcept C2776412080 @default.
• W4200504429 hasConcept C2776706248 @default.
• W4200504429 hasConcept C2776841986 @default.
• W4200504429 hasConcept C2776885963 @default.
• W4200504429 hasConcept C2777090001 @default.
• W4200504429 hasConcept C2777477808 @default.
• W4200504429 hasConcept C2777503454 @default.
• W4200504429 hasConcept C2779727114 @default.
• W4200504429 hasConcept C2780035454 @default.
• W4200504429 hasConcept C2780135775 @default.
• W4200504429 hasConcept C2781197716 @default.
• W4200504429 hasConcept C46762472 @default.
• W4200504429 hasConcept C515207424 @default.
• W4200504429 hasConcept C55493867 @default.
• W4200504429 hasConcept C71924100 @default.
• W4200504429 hasConceptScore W4200504429C118552586 @default.
• W4200504429 hasConceptScore W4200504429C126322002 @default.
• W4200504429 hasConceptScore W4200504429C170493617 @default.
• W4200504429 hasConceptScore W4200504429C185592680 @default.
• W4200504429 hasConceptScore W4200504429C2776412080 @default.
• W4200504429 hasConceptScore W4200504429C2776706248 @default.
• W4200504429 hasConceptScore W4200504429C2776841986 @default.
• W4200504429 hasConceptScore W4200504429C2776885963 @default.
• W4200504429 hasConceptScore W4200504429C2777090001 @default.
• W4200504429 hasConceptScore W4200504429C2777477808 @default.
• W4200504429 hasConceptScore W4200504429C2777503454 @default.
• W4200504429 hasConceptScore W4200504429C2779727114 @default.
• W4200504429 hasConceptScore W4200504429C2780035454 @default.
• W4200504429 hasConceptScore W4200504429C2780135775 @default.
• W4200504429 hasConceptScore W4200504429C2781197716 @default.
• W4200504429 hasConceptScore W4200504429C46762472 @default.
• W4200504429 hasConceptScore W4200504429C515207424 @default.
• W4200504429 hasConceptScore W4200504429C55493867 @default.
• W4200504429 hasConceptScore W4200504429C71924100 @default.
• W4200504429 hasIssue "6" @default.

• next