FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200505538> ?p ?o ?g. }

• W4200505538 endingPage "S37" @default.
• W4200505538 startingPage "S36" @default.
• W4200505538 abstract "Abstract Background Pre-exposure prophylaxis (PrEP) is a highly effective biomedical strategy to decrease Human Immunodeficiency Virus (HIV) acquisition. Effectiveness of oral PrEP is linked to medication adherence. In 2018, Grady Health System (GHS) launched a PrEP program to increase PrEP access among un- and underinsured individuals living in metro Atlanta, Georgia. The purpose of this study is to determine PrEP medication adherence, PrEP discontinuation rates, and associated individual factors of patients enrolled during the first 18 months of the program’s implementation. Methods A single-center, retrospective chart review was conducted on patients enrolled in the GHS PrEP program between June 1, 2018 and February 29, 2020 who received more than one monthly PrEP prescription. Adherence was estimated using the medication possession ratio (MPR). The primary outcome was mean adherence to PrEP. Secondary outcomes include rate of high percent adherence (MPR &gt; 80%), median time of engagement in care, PrEP discontinuation rates, rates of PrEP re-engagement, and individual factors associated with PrEP discontinuation and low adherence. Results This study included 154 patients, 70.8% of them were Black, 62.3% were cisgender men, 59.1% were uninsured, and the mean age was 34. The majority of patients identified as men who have sex with men (51.9%). Mean PrEP adherence was 89.2%; 77.3% of patients demonstrated a high rate of adherence. No individual or social factors were associated with low adherence, but younger age was associated with higher rates of PrEP discontinuation (p&lt; 0.0061). At the end of the follow up period on October 30, 2020, 53.8% of patients were active in the program and 12.7% of those who discontinued had re-engaged with the program. The average length of program engagement was 9.8 months. Table 1. Baseline socio-demographic characteristics (N=154) Table 2. PrEP Adherence and Discontinuation at the GHS PrEP Program from 2018 to 2020 (N=154) Table 4. Multivariate analysis of individual factors associated with PrEP discontinuation and low adherence Conclusion Mean PrEP adherence at a safety net PrEP program in Atlanta was high and PrEP discontinuation rates were comparable to other PrEP clinics nationwide. We found no association with individual factors previously linked to lower adherence, including Black race, younger age, and insurance status. Program-related factors that may have impacted these findings need to be investigated. Other future areas of research include strategies to optimize engagement in care in younger patients. Disclosures Bradley L. Smith, Pharm.D., AAHIVP, Gilead Sciences, Inc (Advisor or Review Panel member)" @default.
• W4200505538 created "2021-12-31" @default.
• W4200505538 creator A5000359779 @default.
• W4200505538 creator A5022305457 @default.
• W4200505538 creator A5023395806 @default.
• W4200505538 creator A5026666508 @default.
• W4200505538 creator A5039656458 @default.
• W4200505538 creator A5065350993 @default.
• W4200505538 creator A5083350924 @default.
• W4200505538 creator A5087280965 @default.
• W4200505538 creator A5089916321 @default.
• W4200505538 date "2021-11-01" @default.
• W4200505538 modified "2023-09-27" @default.
• W4200505538 title "52. PrEP Adherence and Discontinuation at a Pharmacy-Supported PrEP Program in Atlanta, GA" @default.
• W4200505538 doi "https://doi.org/10.1093/ofid/ofab466.052" @default.
• W4200505538 hasPublicationYear "2021" @default.
• W4200505538 type Work @default.
• W4200505538 citedByCount "0" @default.
• W4200505538 crossrefType "journal-article" @default.
• W4200505538 hasAuthorship W4200505538A5000359779 @default.
• W4200505538 hasAuthorship W4200505538A5022305457 @default.
• W4200505538 hasAuthorship W4200505538A5023395806 @default.
• W4200505538 hasAuthorship W4200505538A5026666508 @default.
• W4200505538 hasAuthorship W4200505538A5039656458 @default.
• W4200505538 hasAuthorship W4200505538A5065350993 @default.
• W4200505538 hasAuthorship W4200505538A5083350924 @default.
• W4200505538 hasAuthorship W4200505538A5087280965 @default.
• W4200505538 hasAuthorship W4200505538A5089916321 @default.
• W4200505538 hasBestOaLocation W42005055381 @default.
• W4200505538 hasConcept C104863432 @default.
• W4200505538 hasConcept C126322002 @default.
• W4200505538 hasConcept C159110408 @default.
• W4200505538 hasConcept C160735492 @default.
• W4200505538 hasConcept C162324750 @default.
• W4200505538 hasConcept C2426938 @default.
• W4200505538 hasConcept C2776939746 @default.
• W4200505538 hasConcept C2776983459 @default.
• W4200505538 hasConcept C2778714722 @default.
• W4200505538 hasConcept C2778715236 @default.
• W4200505538 hasConcept C2779496540 @default.
• W4200505538 hasConcept C2983635472 @default.
• W4200505538 hasConcept C3013748606 @default.
• W4200505538 hasConcept C3018553135 @default.
• W4200505538 hasConcept C50522688 @default.
• W4200505538 hasConcept C512399662 @default.
• W4200505538 hasConcept C71924100 @default.
• W4200505538 hasConceptScore W4200505538C104863432 @default.
• W4200505538 hasConceptScore W4200505538C126322002 @default.
• W4200505538 hasConceptScore W4200505538C159110408 @default.
• W4200505538 hasConceptScore W4200505538C160735492 @default.
• W4200505538 hasConceptScore W4200505538C162324750 @default.
• W4200505538 hasConceptScore W4200505538C2426938 @default.
• W4200505538 hasConceptScore W4200505538C2776939746 @default.
• W4200505538 hasConceptScore W4200505538C2776983459 @default.
• W4200505538 hasConceptScore W4200505538C2778714722 @default.
• W4200505538 hasConceptScore W4200505538C2778715236 @default.
• W4200505538 hasConceptScore W4200505538C2779496540 @default.
• W4200505538 hasConceptScore W4200505538C2983635472 @default.
• W4200505538 hasConceptScore W4200505538C3013748606 @default.
• W4200505538 hasConceptScore W4200505538C3018553135 @default.
• W4200505538 hasConceptScore W4200505538C50522688 @default.
• W4200505538 hasConceptScore W4200505538C512399662 @default.
• W4200505538 hasConceptScore W4200505538C71924100 @default.
• W4200505538 hasIssue "Supplement_1" @default.
• W4200505538 hasLocation W42005055381 @default.
• W4200505538 hasLocation W42005055382 @default.
• W4200505538 hasOpenAccess W4200505538 @default.
• W4200505538 hasPrimaryLocation W42005055381 @default.
• W4200505538 hasRelatedWork W2771585761 @default.
• W4200505538 hasRelatedWork W2774072766 @default.
• W4200505538 hasRelatedWork W2981937604 @default.
• W4200505538 hasRelatedWork W2996474769 @default.
• W4200505538 hasRelatedWork W3007495149 @default.
• W4200505538 hasRelatedWork W3027993650 @default.
• W4200505538 hasRelatedWork W3122948194 @default.
• W4200505538 hasRelatedWork W4200505538 @default.
• W4200505538 hasRelatedWork W4295270119 @default.
• W4200505538 hasRelatedWork W4296360213 @default.
• W4200505538 hasVolume "8" @default.
• W4200505538 isParatext "false" @default.
• W4200505538 isRetracted "false" @default.
• W4200505538 workType "article" @default.