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- W4200509532 abstract "β-mannosidosis is a rare autosomal recessive lysosomal storage disease of glycoprotein catabolism caused by a deficiency of β-mannosidase. Clinical presentation includes intellectual deficits, hearing loss, and recurrent respiratory infections. This report describes the dental treatment and follow-up dental care of a child with β-mannosidosis. The patient presented to the dental clinic at the age of 6 years with a localized swelling of his lower posterior teeth. Sickle cell disease and physical and mental developmental delays were noted. Clinical examination revealed a flattened nasal bridge, large head, short neck, open bite, gingival overgrowth, macroglossia, enlarged pulp chambers, and poor oral hygiene. Surgical treatment under general anesthesia included extractions, pulp therapy, and restorations. Four years later, the child returned with generalized gingival inflammation and new carious lesions. Periodontal and restorative treatment was provided, and a preventive dental regimen was established. Mannosidosis cases require complex dental procedures, consultations, and prompt follow-up." @default.
- W4200509532 created "2021-12-31" @default.
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- W4200509532 date "2021-01-01" @default.
- W4200509532 modified "2023-09-23" @default.
- W4200509532 title "Oral manifestation and dental treatment of pediatric patient with beta-mannosidosis: A case report" @default.
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- W4200509532 doi "https://doi.org/10.1177/2050313x211065796" @default.
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