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• W4200511034 abstract "Abstract Background: Falls impose significant health and economic burdens among older populations, making their prevention a priority. Health economic decision models can inform whether the falls prevention intervention represents a cost-effective use of resources and/or meet additional decisional objectives such as reducing social inequities of health. This study aims to conduct a systematic review (SR) of community-based falls prevention models to: (i) systematically identify such models; (ii) synthesise and critically appraise the modelling methods/results; and (iii) formulate methodological and commissioning recommendations. Methods: The SR followed the PRISMA guideline, covering the period 2003-2020, 12 academic databases and grey literature. A study was included if it: targeted community-dwelling persons aged 60 and over and/or aged 50-59 at high falls risk; evaluated intervention(s) designed to reduce falls or fall-related injuries; against any comparator(s); reported outcomes of economic evaluation; used decision modelling; and had English full text. Extracted data fields were grouped under higher categories: (A) model and evaluation overview; (B) falls epidemiology features; (C) falls prevention intervention features; and (D) evaluation methods and outcomes. A checklist for falls prevention economic evaluations assessed reporting/methodological quality. Extracted fields were narratively synthesised and critically appraised to inform methodological and commissioning recommendations. The SR protocol is registered in the Prospective Register of Systematic Reviews (CRD42021232147). Results: 46 models were identified. The most prevalent issue according to the checklist was non-incorporation of all-cause care costs. Based on general population, lifetime models conducting cost-utility analyses, seven interventions produced favourable ICERs relative to no intervention under the cost-effectiveness threshold of £30,000 per QALY gained; of these, results for (1) combined multifactorial and environmental intervention, (2) physical activity promotion for women, and (3) targeted vitamin D supplementation were from validated models. Decision-makers should explore the transferability and feasible reaches of these interventions in their local settings. There was some evidence that exercise and home modification exacerbate existing social inequities of health. Sixteen methodological recommendations were formulated from critical appraisal. Conclusion: There is significant methodological heterogeneity across falls prevention models. This SR’s appraisals of modelling methods should facilitate the conceptualisation of future falls prevention models. Its synthesis of evaluation outcomes could inform commissioning." @default.
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• W4200511034 date "2021-12-06" @default.
• W4200511034 modified "2023-09-27" @default.
• W4200511034 title "Economic Models of Community-Based Falls Prevention: A Systematic Review With Subsequent Commissioning And Methodological Recommendations" @default.
• W4200511034 doi "https://doi.org/10.21203/rs.3.rs-1090843/v1" @default.
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