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- W4200518918 abstract "During the late 1930s, there was a change in emphasis from scleral to corneal contact lenses, which placed different demands on material design and development. Contact lens materials are based on polymer hydrogel or silicone hydrogel, with additional manufacturing technologies employed to produce the final lens. Hyaluronic acid (HA) is one of the most widely used biocompatible polymers for medical use. Since HA is a natural mucopolysaccharide that is widely distributed in the interstices of tissues, it is present in a large amount in the synovial fluid, cartilage, skin, eyeballs, and the like of a human. Three-dimensional tissue constructs with human cells have opened a new avenue of tissue engineering for pharmaceutical and pathophysiological applications. When active substances are encapsulated in drug delivery systems, their bioavailability and therapeutic index can be improved over an extended period of time. A drug delivery system including polymer microspheres has been developed for injection, implants, transdermal patches, and aerosols." @default.
- W4200518918 created "2021-12-31" @default.
- W4200518918 date "2021-09-12" @default.
- W4200518918 modified "2023-10-17" @default.
- W4200518918 title "Medical Applications" @default.
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- W4200518918 doi "https://doi.org/10.1002/9781119851547.ch6" @default.
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