Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200522647> ?p ?o ?g. }
- W4200522647 endingPage "356" @default.
- W4200522647 startingPage "348" @default.
- W4200522647 abstract "To evaluate the utilization of brachytherapy and duration of treatment on overall survival for locally advanced cervical cancer.The National Cancer Database (NCDB) was queried to identify stage II-IVA cervical cancer patients diagnosed in the United States between 2004 and 2015 who were treated with definitive chemoradiation therapy. We defined standard of care (SOC) treatment as receiving external beam radiation therapy (EBRT) and concurrent chemotherapy, brachytherapy (BT), and completing treatment within 8 weeks, and compared SOC treatment to non-SOC. The primary outcome was overall survival (OS). We also evaluated the effect of sociodemographic and clinical variables on receiving SOC.We identified 10,172 women with locally advanced cervical cancer primarily treated with chemotherapy and concurrent EBRT of which 6047 (59.4%) patients received brachytherapy, and only 2978 (29.3%) completed treatment within 8 weeks (SOC). Receipt of SOC was associated with significantly improved overall survival (median OS 131.0 mos vs 95.5 mos, 78.1 mos, 49.2 mos; p < 0.0001). Furthemore, in patients whose treatment extended beyond 8 weeks, brachytherapy was still associated with an improved survival (median OS 95.5 vs 49.2 mos, p < 0.0001). More advanced stage, Non-Hispanic Black race, lower income, lack of insurance or government insurance, less education, and rural residence were associated with decreased likelihood of receiving SOC.Completing standard of care concurrent chemoradiation therapy and brachytherapy in the recommended 8 weeks was associated with a superior overall survival. Patients who received brachytherapy boost show superior survival to patients receiving EBRT alone, regardless of treatment duration. Disparities in care for vulnerable populations highlight the challenges and importance of care coordination for patients with cervical cancer." @default.
- W4200522647 created "2021-12-31" @default.
- W4200522647 creator A5002391153 @default.
- W4200522647 creator A5012199125 @default.
- W4200522647 creator A5024450914 @default.
- W4200522647 creator A5030503143 @default.
- W4200522647 creator A5035956297 @default.
- W4200522647 creator A5044979685 @default.
- W4200522647 creator A5051100455 @default.
- W4200522647 creator A5070123199 @default.
- W4200522647 creator A5087967124 @default.
- W4200522647 date "2022-02-01" @default.
- W4200522647 modified "2023-10-14" @default.
- W4200522647 title "Better late than never: Brachytherapy is more important than timing in treatment of locally advanced cervical cancer" @default.
- W4200522647 cites W1615018686 @default.
- W4200522647 cites W1774451436 @default.
- W4200522647 cites W1985214870 @default.
- W4200522647 cites W1996160554 @default.
- W4200522647 cites W2002122046 @default.
- W4200522647 cites W2004079062 @default.
- W4200522647 cites W2034305918 @default.
- W4200522647 cites W2039067005 @default.
- W4200522647 cites W2061156798 @default.
- W4200522647 cites W2071276232 @default.
- W4200522647 cites W2074365882 @default.
- W4200522647 cites W2076075334 @default.
- W4200522647 cites W2093770400 @default.
- W4200522647 cites W2093777090 @default.
- W4200522647 cites W2105211307 @default.
- W4200522647 cites W2137197268 @default.
- W4200522647 cites W2144044598 @default.
- W4200522647 cites W2152292894 @default.
- W4200522647 cites W2288855485 @default.
- W4200522647 cites W2331715775 @default.
- W4200522647 cites W2333195303 @default.
- W4200522647 cites W2415914679 @default.
- W4200522647 cites W2519514651 @default.
- W4200522647 cites W2555242171 @default.
- W4200522647 cites W2621659165 @default.
- W4200522647 cites W2795364783 @default.
- W4200522647 cites W2795823355 @default.
- W4200522647 cites W2906196686 @default.
- W4200522647 cites W2954705241 @default.
- W4200522647 cites W2968395862 @default.
- W4200522647 cites W2969579014 @default.
- W4200522647 cites W3000734720 @default.
- W4200522647 cites W4376848630 @default.
- W4200522647 doi "https://doi.org/10.1016/j.ygyno.2021.11.015" @default.
- W4200522647 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34865860" @default.
- W4200522647 hasPublicationYear "2022" @default.
- W4200522647 type Work @default.
- W4200522647 citedByCount "8" @default.
- W4200522647 countsByYear W42005226472022 @default.
- W4200522647 countsByYear W42005226472023 @default.
- W4200522647 crossrefType "journal-article" @default.
- W4200522647 hasAuthorship W4200522647A5002391153 @default.
- W4200522647 hasAuthorship W4200522647A5012199125 @default.
- W4200522647 hasAuthorship W4200522647A5024450914 @default.
- W4200522647 hasAuthorship W4200522647A5030503143 @default.
- W4200522647 hasAuthorship W4200522647A5035956297 @default.
- W4200522647 hasAuthorship W4200522647A5044979685 @default.
- W4200522647 hasAuthorship W4200522647A5051100455 @default.
- W4200522647 hasAuthorship W4200522647A5070123199 @default.
- W4200522647 hasAuthorship W4200522647A5087967124 @default.
- W4200522647 hasConcept C121608353 @default.
- W4200522647 hasConcept C126322002 @default.
- W4200522647 hasConcept C143998085 @default.
- W4200522647 hasConcept C146357865 @default.
- W4200522647 hasConcept C151730666 @default.
- W4200522647 hasConcept C2775908122 @default.
- W4200522647 hasConcept C2777416452 @default.
- W4200522647 hasConcept C2778220009 @default.
- W4200522647 hasConcept C509974204 @default.
- W4200522647 hasConcept C71924100 @default.
- W4200522647 hasConcept C86803240 @default.
- W4200522647 hasConceptScore W4200522647C121608353 @default.
- W4200522647 hasConceptScore W4200522647C126322002 @default.
- W4200522647 hasConceptScore W4200522647C143998085 @default.
- W4200522647 hasConceptScore W4200522647C146357865 @default.
- W4200522647 hasConceptScore W4200522647C151730666 @default.
- W4200522647 hasConceptScore W4200522647C2775908122 @default.
- W4200522647 hasConceptScore W4200522647C2777416452 @default.
- W4200522647 hasConceptScore W4200522647C2778220009 @default.
- W4200522647 hasConceptScore W4200522647C509974204 @default.
- W4200522647 hasConceptScore W4200522647C71924100 @default.
- W4200522647 hasConceptScore W4200522647C86803240 @default.
- W4200522647 hasIssue "2" @default.
- W4200522647 hasLocation W42005226471 @default.
- W4200522647 hasLocation W42005226472 @default.
- W4200522647 hasOpenAccess W4200522647 @default.
- W4200522647 hasPrimaryLocation W42005226471 @default.
- W4200522647 hasRelatedWork W2513916013 @default.
- W4200522647 hasRelatedWork W2942848944 @default.
- W4200522647 hasRelatedWork W2966036943 @default.
- W4200522647 hasRelatedWork W3029213237 @default.
- W4200522647 hasRelatedWork W3031343993 @default.
- W4200522647 hasRelatedWork W3104537559 @default.
- W4200522647 hasRelatedWork W4206581437 @default.