FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200526515> ?p ?o ?g. }

• W4200526515 endingPage "103e" @default.
• W4200526515 startingPage "95e" @default.
• W4200526515 abstract "Antiplatelet agents are typically withheld perioperatively because of bleeding concerns. Dual antiplatelet therapy, such as aspirin and clopidogrel, has significant morbidity and mortality benefits in patients with ischemic heart disease or peripheral vascular disease. This study aims to evaluate the impact of perioperative dual antiplatelet therapy in the lower extremity free tissue transfer population.Lower extremity free tissue transfers performed by the senior author (K.K.E.) from 2011 to 2019 were retrospectively reviewed. Demographics, comorbidities, perioperative dual antiplatelet therapy, and free tissue transfer characteristics were recorded. Outcomes of interest included flap success, hematoma formation, blood transfusion requirements, and cardiac event occurrence.One hundred ninety-five free tissue transfers were included. Median age at the time of free tissue transfer was 56.5 years. Median Charlson Comorbidity Index was 3. Thirty-four patients were on clopidogrel, which was either withheld (n = 20) or continued (n = 14) on the day of free tissue transfer. Incidence of blood transfusion was significantly higher in both the withheld and continued versus nonclopidogrel groups. Flap success was statistically equivalent between groups (withheld, 90.0 percent; continued, 92.9 percent; nonclopidogrel, 95.0 percent; p = 0.346). Cardiac events occurred most often in the continued group (21.4 percent) compared to the withheld (5.0 percent) and nonclopidogrel (0.6 percent) groups. On multivariate analysis, holding clopidogrel remained significant for increased odds of postoperative transfusion. The clopidogrel group was no longer significant for intraoperative transfusion.Despite increases in volume of blood products transfused, free tissue transfer can be performed safely with perioperative dual antiplatelet therapy. Withholding dual antiplatelet therapy on the day of free tissue transfer was not associated with decreased intraoperative transfusion; thus, dual antiplatelet therapy can safely be continued throughout the operative course to minimize cardiovascular risk.Therapeutic, III." @default.
• W4200526515 created "2021-12-31" @default.
• W4200526515 creator A5007191169 @default.
• W4200526515 creator A5009879127 @default.
• W4200526515 creator A5026246165 @default.
• W4200526515 creator A5046491701 @default.
• W4200526515 creator A5055614632 @default.
• W4200526515 creator A5059348383 @default.
• W4200526515 creator A5072350157 @default.
• W4200526515 creator A5072512492 @default.
• W4200526515 date "2021-12-21" @default.
• W4200526515 modified "2023-10-17" @default.
• W4200526515 title "Should Antiplatelet Therapy Be Withheld Perioperatively? The First Study Examining Outcomes in Patients Receiving Dual Antiplatelet Therapy in the Lower Extremity Free Flap Population" @default.
• W4200526515 cites W1541363229 @default.
• W4200526515 cites W1964801580 @default.
• W4200526515 cites W1993089452 @default.
• W4200526515 cites W2000129463 @default.
• W4200526515 cites W2010496221 @default.
• W4200526515 cites W2016594382 @default.
• W4200526515 cites W2022356593 @default.
• W4200526515 cites W2024352468 @default.
• W4200526515 cites W2030405104 @default.
• W4200526515 cites W2037668591 @default.
• W4200526515 cites W2048732439 @default.
• W4200526515 cites W2062966560 @default.
• W4200526515 cites W2063095595 @default.
• W4200526515 cites W2078178450 @default.
• W4200526515 cites W2087481165 @default.
• W4200526515 cites W2089352331 @default.
• W4200526515 cites W2101840986 @default.
• W4200526515 cites W2144730936 @default.
• W4200526515 cites W2151333262 @default.
• W4200526515 cites W2151610422 @default.
• W4200526515 cites W2155421471 @default.
• W4200526515 cites W2327931724 @default.
• W4200526515 cites W2345022629 @default.
• W4200526515 cites W2467139046 @default.
• W4200526515 cites W2534235959 @default.
• W4200526515 cites W2612463268 @default.
• W4200526515 cites W2782945788 @default.
• W4200526515 cites W2801462821 @default.
• W4200526515 cites W2917715501 @default.
• W4200526515 cites W2923415813 @default.
• W4200526515 cites W3014048838 @default.
• W4200526515 cites W4239001534 @default.
• W4200526515 cites W4289886312 @default.
• W4200526515 doi "https://doi.org/10.1097/prs.0000000000008666" @default.
• W4200526515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34936629" @default.
• W4200526515 hasPublicationYear "2021" @default.
• W4200526515 type Work @default.
• W4200526515 citedByCount "1" @default.
• W4200526515 countsByYear W42005265152023 @default.
• W4200526515 crossrefType "journal-article" @default.
• W4200526515 hasAuthorship W4200526515A5007191169 @default.
• W4200526515 hasAuthorship W4200526515A5009879127 @default.
• W4200526515 hasAuthorship W4200526515A5026246165 @default.
• W4200526515 hasAuthorship W4200526515A5046491701 @default.
• W4200526515 hasAuthorship W4200526515A5055614632 @default.
• W4200526515 hasAuthorship W4200526515A5059348383 @default.
• W4200526515 hasAuthorship W4200526515A5072350157 @default.
• W4200526515 hasAuthorship W4200526515A5072512492 @default.
• W4200526515 hasConcept C126322002 @default.
• W4200526515 hasConcept C141071460 @default.
• W4200526515 hasConcept C2777628954 @default.
• W4200526515 hasConcept C2777849778 @default.
• W4200526515 hasConcept C2779159551 @default.
• W4200526515 hasConcept C2780014101 @default.
• W4200526515 hasConcept C2908647359 @default.
• W4200526515 hasConcept C31174226 @default.
• W4200526515 hasConcept C42219234 @default.
• W4200526515 hasConcept C71924100 @default.
• W4200526515 hasConcept C99454951 @default.
• W4200526515 hasConceptScore W4200526515C126322002 @default.
• W4200526515 hasConceptScore W4200526515C141071460 @default.
• W4200526515 hasConceptScore W4200526515C2777628954 @default.
• W4200526515 hasConceptScore W4200526515C2777849778 @default.
• W4200526515 hasConceptScore W4200526515C2779159551 @default.
• W4200526515 hasConceptScore W4200526515C2780014101 @default.
• W4200526515 hasConceptScore W4200526515C2908647359 @default.
• W4200526515 hasConceptScore W4200526515C31174226 @default.
• W4200526515 hasConceptScore W4200526515C42219234 @default.
• W4200526515 hasConceptScore W4200526515C71924100 @default.
• W4200526515 hasConceptScore W4200526515C99454951 @default.
• W4200526515 hasIssue "1" @default.
• W4200526515 hasLocation W42005265151 @default.
• W4200526515 hasLocation W42005265152 @default.
• W4200526515 hasOpenAccess W4200526515 @default.
• W4200526515 hasPrimaryLocation W42005265151 @default.
• W4200526515 hasRelatedWork W1972991584 @default.
• W4200526515 hasRelatedWork W2039043600 @default.
• W4200526515 hasRelatedWork W2351585108 @default.
• W4200526515 hasRelatedWork W2351906597 @default.
• W4200526515 hasRelatedWork W2358011965 @default.
• W4200526515 hasRelatedWork W2375932762 @default.
• W4200526515 hasRelatedWork W24224509 @default.
• W4200526515 hasRelatedWork W2807843051 @default.
• W4200526515 hasRelatedWork W2883947381 @default.
• W4200526515 hasRelatedWork W4251016252 @default.

• next