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• W4200526820 abstract "Environmental risk factors such as Western diet, pollution, alcoholism, tobacco intake, and physical inactivity may be associated with lower intake of Mediterranean-style foods, which may predispose the person to deficiencies in antioxidant vitamins and minerals in all the body systems. A deficiency in these vitamins and minerals, as well as other antioxidant, predisposes the person to oxidative stress and inflammation leading to increased risk of non-communicable diseases. Therefore antioxidant vitamin deficiencies appear to be important in the pathogenesis of cardiovascular diseases (CVDs) and other chronic diseases. Epidemiological studies have shown that vitamin A, E, D, and C and beta-carotene as well as folic acid, B vitamins, niacin, magnesium, zinc, selenium, and chromium are inversely associated with risk for morbidity and mortality due to CVDs and cancer. However, randomized, controlled intervention trials showed no evidence of benefit from vitamin supplementation in CVDs and cancers, and adverse effects were observed in some of the important studies. Hence there is no evidence to support the use of vitamins in the prevention of CVDs and cancer. There is some evidence that higher doses of vitamin C as well as other micronutrients such as iron, calcium, magnesium, folic acid, B vitamins, and vitamin D may provide protection to certain populations, such as pregnant women and individuals with undernutrition. Further studies are necessary to determine the role of vitamins and minerals in children, chronically ill elderly people, and cases of malnutrition." @default.
• W4200526820 created "2021-12-31" @default.
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• W4200526820 date "2022-01-01" @default.
• W4200526820 modified "2023-09-28" @default.
• W4200526820 title "Vitamins and minerals as nutraceuticals in cardiovascular diseases and other chronic diseases" @default.
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