Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200528059> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4200528059 abstract "Abstract Venous thromboembolic disease is a complex and multifactorial pathology, the result of the interaction of both genetic and environmental factors. The Virchow triad, first described in 1859, is still valid to explain the pathogenesis of thrombosis, where three main factors are reflected: a) hypercoagulable state; b) impaired blood flow; c) endothelial injury. The outbreak of a new COVID-19 pandemic has led to drastic confinement measures, with the consequent syndrome of immobility, as occurred in Spain between the months of March to June 2020. Pregnancy and hormonal contraception have proven to be an environmental factor predisposing to venous thrombosis. The presence of genetic factors, such as the mutation of the prothrombin gene G20210A, has been shown to be a risk factor for the presentation of venous thrombosis. We present the case of a 23-year-old non-smoking woman, a heterozygous carrier of a prothrombin gene mutation G20210A (hypercoagulability), who after confinement due to COVID-19 (impaired blood flow due to immobility) and use of hormonal patch contraceptives (endothelial abnormality), triggered deep vein thrombosis (DVT) / pulmonary thromboembolism (PE) that required hospital admission; and who, after rapid withdrawal of anticoagulant treatment, presented a second and a third episode of DVT. We highlight the usefulness of evaluating risk factors in G20210A heterozygous patients and the proper management of anticoagulation to avoid recurrences in patients susceptible to DVT / PE." @default.
- W4200528059 created "2021-12-31" @default.
- W4200528059 creator A5003502343 @default.
- W4200528059 creator A5049055505 @default.
- W4200528059 creator A5051755708 @default.
- W4200528059 creator A5057942703 @default.
- W4200528059 creator A5070005641 @default.
- W4200528059 creator A5070510127 @default.
- W4200528059 creator A5084904076 @default.
- W4200528059 creator A5091767492 @default.
- W4200528059 date "2021-12-20" @default.
- W4200528059 modified "2023-09-28" @default.
- W4200528059 title "Immobility due to COVID-19 confinement, use of contraceptives and presence of the G20210A mutation. Validity of the Virchow triad for the presentation of Deep Venous Thrombosis and Pulmonary Thromboembolism." @default.
- W4200528059 doi "https://doi.org/10.21203/rs.3.rs-1104706/v2" @default.
- W4200528059 hasPublicationYear "2021" @default.
- W4200528059 type Work @default.
- W4200528059 citedByCount "0" @default.
- W4200528059 crossrefType "posted-content" @default.
- W4200528059 hasAuthorship W4200528059A5003502343 @default.
- W4200528059 hasAuthorship W4200528059A5049055505 @default.
- W4200528059 hasAuthorship W4200528059A5051755708 @default.
- W4200528059 hasAuthorship W4200528059A5057942703 @default.
- W4200528059 hasAuthorship W4200528059A5070005641 @default.
- W4200528059 hasAuthorship W4200528059A5070510127 @default.
- W4200528059 hasAuthorship W4200528059A5084904076 @default.
- W4200528059 hasAuthorship W4200528059A5091767492 @default.
- W4200528059 hasBestOaLocation W42005280591 @default.
- W4200528059 hasConcept C126322002 @default.
- W4200528059 hasConcept C164705383 @default.
- W4200528059 hasConcept C2776265017 @default.
- W4200528059 hasConcept C2777175894 @default.
- W4200528059 hasConcept C2777872019 @default.
- W4200528059 hasConcept C2778959117 @default.
- W4200528059 hasConcept C2780011451 @default.
- W4200528059 hasConcept C2780868729 @default.
- W4200528059 hasConcept C71924100 @default.
- W4200528059 hasConceptScore W4200528059C126322002 @default.
- W4200528059 hasConceptScore W4200528059C164705383 @default.
- W4200528059 hasConceptScore W4200528059C2776265017 @default.
- W4200528059 hasConceptScore W4200528059C2777175894 @default.
- W4200528059 hasConceptScore W4200528059C2777872019 @default.
- W4200528059 hasConceptScore W4200528059C2778959117 @default.
- W4200528059 hasConceptScore W4200528059C2780011451 @default.
- W4200528059 hasConceptScore W4200528059C2780868729 @default.
- W4200528059 hasConceptScore W4200528059C71924100 @default.
- W4200528059 hasLocation W42005280591 @default.
- W4200528059 hasOpenAccess W4200528059 @default.
- W4200528059 hasPrimaryLocation W42005280591 @default.
- W4200528059 hasRelatedWork W1828798278 @default.
- W4200528059 hasRelatedWork W2000380123 @default.
- W4200528059 hasRelatedWork W2050658763 @default.
- W4200528059 hasRelatedWork W2097472521 @default.
- W4200528059 hasRelatedWork W2098487730 @default.
- W4200528059 hasRelatedWork W2173718391 @default.
- W4200528059 hasRelatedWork W2419059933 @default.
- W4200528059 hasRelatedWork W2981730791 @default.
- W4200528059 hasRelatedWork W3119849786 @default.
- W4200528059 hasRelatedWork W4220829352 @default.
- W4200528059 isParatext "false" @default.
- W4200528059 isRetracted "false" @default.
- W4200528059 workType "article" @default.