FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200529482> ?p ?o ?g. }

• W4200529482 abstract "Epstein-Barr virus (EBV) causes infectious mononucleosis (IM) that can lead to chronic fatigue syndrome. The CEBA-project (Chronic fatigue following acute EBV infection in Adolescents) has followed 200 patients with IM and here we present an immunological profiling of adolescents with IM related to clinical characteristics.Patients were sampled within 6 weeks of debut of symptoms and after 6 months. Peripheral blood mononuclear cells (PBMC) were cultured and stimulated in vitro (n=68), and supernatants analyzed for cytokine release. Plasma was analyzed for inflammatory markers (n=200). The Chalder Fatigue Questionnaire diagnosed patients with and without chronic fatigue at 6 months (CF+ and CF- group, respectively) (n=32 and n=91, in vitro and plasma cohorts, respectively.Broad activation of PBMC at baseline, with high levels of RANTES (Regulated on activation, normal T-cell expressed and secreted) in the CF+ group, and broad inflammatory response in plasma with high levels of T-cell markers was obeserved. At 6 months, there was an increased β-agonist response and RANTES was still elevated in cultures from the CF+ group. Plasma showed decrease of inflammatory markers except for CRP which was consistently elevated in the CF+ group.Patients developing chronic fatigue after IM have signs of T-cell activation and low-grade chronic inflammation at baseline and after 6 months.https://clinicaltrials.gov/, identifier NCT02335437." @default.
• W4200529482 created "2021-12-31" @default.
• W4200529482 creator A5034439136 @default.
• W4200529482 creator A5039625009 @default.
• W4200529482 creator A5056743131 @default.
• W4200529482 creator A5061250666 @default.
• W4200529482 creator A5078394585 @default.
• W4200529482 creator A5083687567 @default.
• W4200529482 creator A5087063624 @default.
• W4200529482 creator A5087127940 @default.
• W4200529482 date "2021-12-20" @default.
• W4200529482 modified "2023-10-16" @default.
• W4200529482 title "Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue" @default.
• W4200529482 cites W1970646683 @default.
• W4200529482 cites W1986366990 @default.
• W4200529482 cites W1988775430 @default.
• W4200529482 cites W2013906360 @default.
• W4200529482 cites W2051892927 @default.
• W4200529482 cites W2059954439 @default.
• W4200529482 cites W2085735549 @default.
• W4200529482 cites W2093534560 @default.
• W4200529482 cites W2112802342 @default.
• W4200529482 cites W2121629072 @default.
• W4200529482 cites W2136415723 @default.
• W4200529482 cites W2154881642 @default.
• W4200529482 cites W2218054076 @default.
• W4200529482 cites W2336628460 @default.
• W4200529482 cites W2612662388 @default.
• W4200529482 cites W2741112791 @default.
• W4200529482 cites W2790767990 @default.
• W4200529482 cites W2790846487 @default.
• W4200529482 cites W2801029519 @default.
• W4200529482 cites W2893603535 @default.
• W4200529482 cites W2909909804 @default.
• W4200529482 cites W2941870996 @default.
• W4200529482 cites W2960589007 @default.
• W4200529482 cites W2995337439 @default.
• W4200529482 cites W2996538150 @default.
• W4200529482 doi "https://doi.org/10.3389/fimmu.2021.715102" @default.
• W4200529482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34987499" @default.
• W4200529482 hasPublicationYear "2021" @default.
• W4200529482 type Work @default.
• W4200529482 citedByCount "9" @default.
• W4200529482 countsByYear W42005294822022 @default.
• W4200529482 countsByYear W42005294822023 @default.
• W4200529482 crossrefType "journal-article" @default.
• W4200529482 hasAuthorship W4200529482A5034439136 @default.
• W4200529482 hasAuthorship W4200529482A5039625009 @default.
• W4200529482 hasAuthorship W4200529482A5056743131 @default.
• W4200529482 hasAuthorship W4200529482A5061250666 @default.
• W4200529482 hasAuthorship W4200529482A5078394585 @default.
• W4200529482 hasAuthorship W4200529482A5083687567 @default.
• W4200529482 hasAuthorship W4200529482A5087063624 @default.
• W4200529482 hasAuthorship W4200529482A5087127940 @default.
• W4200529482 hasBestOaLocation W42005294821 @default.
• W4200529482 hasConcept C126322002 @default.
• W4200529482 hasConcept C137061746 @default.
• W4200529482 hasConcept C202751555 @default.
• W4200529482 hasConcept C203014093 @default.
• W4200529482 hasConcept C2522874641 @default.
• W4200529482 hasConcept C2776129502 @default.
• W4200529482 hasConcept C2776914184 @default.
• W4200529482 hasConcept C2778690821 @default.
• W4200529482 hasConcept C2779566273 @default.
• W4200529482 hasConcept C3020395016 @default.
• W4200529482 hasConcept C55493867 @default.
• W4200529482 hasConcept C71924100 @default.
• W4200529482 hasConcept C86803240 @default.
• W4200529482 hasConceptScore W4200529482C126322002 @default.
• W4200529482 hasConceptScore W4200529482C137061746 @default.
• W4200529482 hasConceptScore W4200529482C202751555 @default.
• W4200529482 hasConceptScore W4200529482C203014093 @default.
• W4200529482 hasConceptScore W4200529482C2522874641 @default.
• W4200529482 hasConceptScore W4200529482C2776129502 @default.
• W4200529482 hasConceptScore W4200529482C2776914184 @default.
• W4200529482 hasConceptScore W4200529482C2778690821 @default.
• W4200529482 hasConceptScore W4200529482C2779566273 @default.
• W4200529482 hasConceptScore W4200529482C3020395016 @default.
• W4200529482 hasConceptScore W4200529482C55493867 @default.
• W4200529482 hasConceptScore W4200529482C71924100 @default.
• W4200529482 hasConceptScore W4200529482C86803240 @default.
• W4200529482 hasLocation W42005294821 @default.
• W4200529482 hasLocation W42005294822 @default.
• W4200529482 hasLocation W42005294823 @default.
• W4200529482 hasLocation W42005294824 @default.
• W4200529482 hasLocation W42005294825 @default.
• W4200529482 hasOpenAccess W4200529482 @default.
• W4200529482 hasPrimaryLocation W42005294821 @default.
• W4200529482 hasRelatedWork W2021748243 @default.
• W4200529482 hasRelatedWork W2030238129 @default.
• W4200529482 hasRelatedWork W2049182512 @default.
• W4200529482 hasRelatedWork W2062790308 @default.
• W4200529482 hasRelatedWork W2087976276 @default.
• W4200529482 hasRelatedWork W2113148377 @default.
• W4200529482 hasRelatedWork W2276972059 @default.
• W4200529482 hasRelatedWork W2778574415 @default.
• W4200529482 hasRelatedWork W4200529482 @default.
• W4200529482 hasRelatedWork W9581748 @default.
• W4200529482 hasVolume "12" @default.
• W4200529482 isParatext "false" @default.

• next