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- W4200531904 endingPage "450" @default.
- W4200531904 startingPage "431" @default.
- W4200531904 abstract "The interpretation of fetal heart rate (FHR) patterns is the only available method to continuously monitor fetal well-being during labour. One of the most important yet contentious aspects of the FHR pattern is changes in FHR variability (FHRV). Some clinical studies suggest that loss of FHRV during labour is a sign of fetal compromise so this is reflected in practice guidelines. Surprisingly, there is little systematic evidence to support this observation. In this review we methodically dissect the potential pathways controlling FHRV during labour-like hypoxaemia. Before labour, FHRV is controlled by the combined activity of the parasympathetic and sympathetic nervous systems, in part regulated by a complex interplay between fetal sleep state and behaviour. By contrast, preclinical studies using multiple autonomic blockades have now shown that sympathetic neural control of FHRV was potently suppressed between periods of labour-like hypoxaemia, and thus, that the parasympathetic system is the sole neural regulator of FHRV once FHR decelerations are present during labour. We further discuss the pattern of changes in FHRV during progressive fetal compromise and highlight potential biochemical, behavioural and clinical factors that may regulate parasympathetic-mediated FHRV during labour. Further studies are needed to investigate the regulators of parasympathetic activity to better understand the dynamic changes in FHRV and their true utility during labour." @default.
- W4200531904 created "2021-12-31" @default.
- W4200531904 creator A5021565295 @default.
- W4200531904 creator A5024849794 @default.
- W4200531904 creator A5035531146 @default.
- W4200531904 creator A5039019537 @default.
- W4200531904 creator A5041737432 @default.
- W4200531904 creator A5047041488 @default.
- W4200531904 creator A5055000902 @default.
- W4200531904 creator A5072063662 @default.
- W4200531904 date "2022-01-17" @default.
- W4200531904 modified "2023-10-10" @default.
- W4200531904 title "Physiological control of fetal heart rate variability during labour: implications and controversies" @default.
- W4200531904 cites W1486674181 @default.
- W4200531904 cites W1522527561 @default.
- W4200531904 cites W1535291517 @default.
- W4200531904 cites W1557124023 @default.
- W4200531904 cites W1563556120 @default.
- W4200531904 cites W1565097905 @default.
- W4200531904 cites W1605582164 @default.
- W4200531904 cites W1875915783 @default.
- W4200531904 cites W1902039366 @default.
- W4200531904 cites W1931727703 @default.
- W4200531904 cites W1961621860 @default.
- W4200531904 cites W1963583436 @default.
- W4200531904 cites W1964439184 @default.
- W4200531904 cites W1966299575 @default.
- W4200531904 cites W1966418572 @default.
- W4200531904 cites W1967315322 @default.
- W4200531904 cites W1968227908 @default.
- W4200531904 cites W1968413151 @default.
- W4200531904 cites W1971224092 @default.
- W4200531904 cites W1972181163 @default.
- W4200531904 cites W1974070751 @default.
- W4200531904 cites W1975714289 @default.
- W4200531904 cites W1983251001 @default.
- W4200531904 cites W1984892864 @default.
- W4200531904 cites W1987737506 @default.
- W4200531904 cites W1988575365 @default.
- W4200531904 cites W1992047100 @default.
- W4200531904 cites W1992778608 @default.
- W4200531904 cites W1993546852 @default.
- W4200531904 cites W2000609745 @default.
- W4200531904 cites W2003354105 @default.
- W4200531904 cites W2004311975 @default.
- W4200531904 cites W2004491405 @default.
- W4200531904 cites W2005720877 @default.
- W4200531904 cites W2006654146 @default.
- W4200531904 cites W2008878099 @default.
- W4200531904 cites W2015659439 @default.
- W4200531904 cites W2016489696 @default.
- W4200531904 cites W2020840913 @default.
- W4200531904 cites W2021597987 @default.
- W4200531904 cites W2025991670 @default.
- W4200531904 cites W2027480337 @default.
- W4200531904 cites W2030107446 @default.
- W4200531904 cites W2032730099 @default.
- W4200531904 cites W2032791162 @default.
- W4200531904 cites W2040318851 @default.
- W4200531904 cites W2041590388 @default.
- W4200531904 cites W2042898259 @default.
- W4200531904 cites W2043672068 @default.
- W4200531904 cites W2044362164 @default.
- W4200531904 cites W2044852007 @default.
- W4200531904 cites W2048689237 @default.
- W4200531904 cites W2050487194 @default.
- W4200531904 cites W2051253089 @default.
- W4200531904 cites W2052758549 @default.
- W4200531904 cites W2053769666 @default.
- W4200531904 cites W2053853941 @default.
- W4200531904 cites W2053854848 @default.
- W4200531904 cites W2055205986 @default.
- W4200531904 cites W2060279163 @default.
- W4200531904 cites W2060856095 @default.
- W4200531904 cites W2062372784 @default.
- W4200531904 cites W2062537021 @default.
- W4200531904 cites W2064474297 @default.
- W4200531904 cites W2066009922 @default.
- W4200531904 cites W2067407353 @default.
- W4200531904 cites W2067735113 @default.
- W4200531904 cites W2072015224 @default.
- W4200531904 cites W2072562682 @default.
- W4200531904 cites W2072691177 @default.
- W4200531904 cites W2073938984 @default.
- W4200531904 cites W2077573465 @default.
- W4200531904 cites W2078693874 @default.
- W4200531904 cites W2081465735 @default.
- W4200531904 cites W2083733099 @default.
- W4200531904 cites W2084846100 @default.
- W4200531904 cites W2088252999 @default.
- W4200531904 cites W2090062755 @default.
- W4200531904 cites W2090120142 @default.
- W4200531904 cites W2090314939 @default.
- W4200531904 cites W2093950834 @default.
- W4200531904 cites W2093975802 @default.
- W4200531904 cites W2094205289 @default.
- W4200531904 cites W2095445560 @default.
- W4200531904 cites W2100696828 @default.