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- W4200548501 endingPage "756" @default.
- W4200548501 startingPage "735" @default.
- W4200548501 abstract "Mannich bases identified by Professor Carl Mannich have been the most extensively explored scaffolds for more than 100 years now. The versatile biological roles that they play have promoted their applications in many clinical conditions. The present review highlights the application of Mannich bases as cytotoxic agents, categorizing them into synthetic, semisynthetic and prodrugs classes and gives an exhaustive account of the work reported in the last two decades. The methods of synthesis of these cytotoxic agents, their anti-cancer potential in various cell lines and promising leads for future drug development have also been discussed. Structure-activity relationships along with the targets on which these cytotoxic Mannich bases act have been included as well." @default.
- W4200548501 created "2021-12-31" @default.
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- W4200548501 creator A5087290514 @default.
- W4200548501 date "2022-08-01" @default.
- W4200548501 modified "2023-09-23" @default.
- W4200548501 title "Mannich Bases: Centrality in Cytotoxic Drug Design" @default.
- W4200548501 cites W1244116556 @default.
- W4200548501 cites W1416485680 @default.
- W4200548501 cites W1457117875 @default.
- W4200548501 cites W1521652143 @default.
- W4200548501 cites W1878707781 @default.
- W4200548501 cites W1900824189 @default.
- W4200548501 cites W1965226930 @default.
- W4200548501 cites W1969876766 @default.
- W4200548501 cites W1971080824 @default.
- W4200548501 cites W1979153024 @default.
- W4200548501 cites W1979657535 @default.
- W4200548501 cites W1982271708 @default.
- W4200548501 cites W1987489104 @default.
- W4200548501 cites W1995591348 @default.
- W4200548501 cites W2000061453 @default.
- W4200548501 cites W2000704821 @default.
- W4200548501 cites W2005200305 @default.
- W4200548501 cites W2014527391 @default.
- W4200548501 cites W2027182632 @default.
- W4200548501 cites W2027346421 @default.
- W4200548501 cites W2028595772 @default.
- W4200548501 cites W2044177750 @default.
- W4200548501 cites W2048441067 @default.
- W4200548501 cites W2053077214 @default.
- W4200548501 cites W2057848370 @default.
- W4200548501 cites W2060101089 @default.
- W4200548501 cites W2065630179 @default.
- W4200548501 cites W2069595441 @default.
- W4200548501 cites W2072793080 @default.
- W4200548501 cites W2100719274 @default.
- W4200548501 cites W2102183947 @default.
- W4200548501 cites W2107714285 @default.
- W4200548501 cites W2120154243 @default.
- W4200548501 cites W2122005207 @default.
- W4200548501 cites W2134265484 @default.
- W4200548501 cites W2136011430 @default.
- W4200548501 cites W2141144571 @default.
- W4200548501 cites W2141497020 @default.
- W4200548501 cites W2145786098 @default.
- W4200548501 cites W2147792248 @default.
- W4200548501 cites W2164187183 @default.
- W4200548501 cites W2166765047 @default.
- W4200548501 cites W2171126186 @default.
- W4200548501 cites W2252500298 @default.
- W4200548501 cites W2320163152 @default.
- W4200548501 cites W2325963753 @default.
- W4200548501 cites W2326479765 @default.
- W4200548501 cites W2333089669 @default.
- W4200548501 cites W2353789499 @default.
- W4200548501 cites W2406913770 @default.
- W4200548501 cites W2413587347 @default.
- W4200548501 cites W2517383615 @default.
- W4200548501 cites W2556941899 @default.
- W4200548501 cites W2559918222 @default.
- W4200548501 cites W2618511195 @default.
- W4200548501 cites W2618631136 @default.
- W4200548501 cites W2625008318 @default.
- W4200548501 cites W2626660961 @default.
- W4200548501 cites W2735950720 @default.
- W4200548501 cites W2749887563 @default.
- W4200548501 cites W2764174910 @default.
- W4200548501 cites W2767285849 @default.
- W4200548501 cites W2796260470 @default.
- W4200548501 cites W2797837302 @default.
- W4200548501 cites W2804449354 @default.
- W4200548501 cites W2883671449 @default.
- W4200548501 cites W2899807611 @default.
- W4200548501 cites W2903497270 @default.
- W4200548501 cites W2909527160 @default.
- W4200548501 cites W2941186255 @default.
- W4200548501 cites W2949222898 @default.
- W4200548501 cites W2951091216 @default.
- W4200548501 cites W2951816265 @default.
- W4200548501 cites W2951890455 @default.
- W4200548501 cites W2953806257 @default.
- W4200548501 cites W2958712449 @default.
- W4200548501 cites W2997468590 @default.
- W4200548501 cites W3003681926 @default.