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- W4200556218 endingPage "370" @default.
- W4200556218 startingPage "343" @default.
- W4200556218 abstract "Nanotechnology has played a significant role in the field of bone tissue regeneration, owing to its size-dependent characteristics and special structures. Bioceramic materials have been extensively researched to relate with hierarchical structures of natural bone tissues and to form bone-like scaffolds. The materials are designed to repair, restore, and improve the function of damaged and diseased part of host body. Bioactive glass, glass–ceramics, and calcium phosphates have been widely used in delivering antibiotics, biologically active agents, growth factors, nucleic acids, or peptides at the cure site. Sometimes, to avoid post-surgical infections, nanomaterials' surfaces have been modified and loaded with specific antibiotics to avoid bacterial infections and biofilm formation thereafter. These materials are considered as multifunctional due to their osteoconductive, osteoproductive, and osteoinductive properties as well as due to their ability to load, shield, and deliver the required therapeutic agents at the target site. Therefore, these biomaterials are an ideal and promising component for preparation of scaffolds in bone tissue engineering. This chapter thus gives information about the generations of bioactive glasses, especially the mesoporous bioactive glass, their different synthesis techniques, mechanism behind their bioactivity, roles of therapeutic ion doping, drug delivery and surface functionalization, and detailed in vivo studies toward bone tissue regeneration applications." @default.
- W4200556218 created "2021-12-31" @default.
- W4200556218 creator A5017997606 @default.
- W4200556218 creator A5025563982 @default.
- W4200556218 creator A5072175984 @default.
- W4200556218 date "2021-12-10" @default.
- W4200556218 modified "2023-10-12" @default.
- W4200556218 title "Mesoporous Bioactive Glass for Bone Tissue Regeneration and Drug Delivery" @default.
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