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- W4200559545 abstract "With the dramatic increase in cancer incidence all over the world in the last decades, studies on identifying novel efficient anti-cancer agents have been intensified. Historically, natural products have represented one of the most important sources of new lead compounds with a wide range of biological activities. In this article, the multifaceted anti-cancer action of propolis-derived flavonoid, galangin, is presented, discussing its antioxidant, anti-inflammatory, antiproliferative, pro-apoptotic, anti-angiogenic, and anti-metastatic effects in various cancer cells. In addition, co-effects with standard chemotherapeutic drugs as well as other natural compounds are also under discussion, besides highlighting modern nanotechnological advancements for overcoming the low bioavailability issue characteristic of galangin. Although further studies are needed for confirming the anti-cancer potential of galangin in vivo malignant systems, exploring this natural compound might open new perspectives in molecular oncology." @default.
- W4200559545 created "2021-12-31" @default.
- W4200559545 creator A5005552049 @default.
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- W4200559545 creator A5085290172 @default.
- W4200559545 date "2021-12-14" @default.
- W4200559545 modified "2023-09-30" @default.
- W4200559545 title "Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets" @default.
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