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- W4200559809 abstract "Population aging is occurring rapidly worldwide, challenging the global economy and healthcare services. Brain aging is a significant contributor to various age-related neurological and neuropsychological disorders, including Alzheimer's disease and Parkinson's disease. Several extrinsic factors, such as exposure to ionizing radiation, can accelerate senescence. Multiple human and animal studies have reported that exposure to ionizing radiation can have varied effects on organ aging and lead to the prolongation or shortening of life span depending on the radiation dose or dose rate. This paper reviews the effects of radiation on the aging of different types of brain cells, including neurons, microglia, astrocytes, and cerebral endothelial cells. Further, the relevant molecular mechanisms are discussed. Overall, this review highlights how radiation-induced senescence in different cell types may lead to brain aging, which could result in the development of various neurological and neuropsychological disorders. Therefore, treatment targeting radiation-induced oxidative stress and neuroinflammation may prevent radiation-induced brain aging and the neurological and neuropsychological disorders it may cause." @default.
- W4200559809 created "2021-12-31" @default.
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- W4200559809 date "2021-12-17" @default.
- W4200559809 modified "2023-10-17" @default.
- W4200559809 title "Ionizing Radiation-Induced Brain Cell Aging and the Potential Underlying Molecular Mechanisms" @default.
- W4200559809 cites W1489456875 @default.
- W4200559809 cites W1509805561 @default.
- W4200559809 cites W1520954824 @default.
- W4200559809 cites W1543224150 @default.
- W4200559809 cites W1565351177 @default.
- W4200559809 cites W1590561480 @default.
- W4200559809 cites W1592054096 @default.
- W4200559809 cites W1609916908 @default.
- W4200559809 cites W1688786414 @default.
- W4200559809 cites W1726562753 @default.
- W4200559809 cites W1814306862 @default.
- W4200559809 cites W1821766353 @default.
- W4200559809 cites W1955393669 @default.
- W4200559809 cites W1964483580 @default.
- W4200559809 cites W1966056603 @default.
- W4200559809 cites W1969072319 @default.
- W4200559809 cites W1970924670 @default.
- W4200559809 cites W1974396693 @default.
- W4200559809 cites W1976391651 @default.
- W4200559809 cites W1977559188 @default.
- W4200559809 cites W1981323260 @default.
- W4200559809 cites W1982481909 @default.
- W4200559809 cites W1983835791 @default.
- W4200559809 cites W1985792602 @default.
- W4200559809 cites W1989754990 @default.
- W4200559809 cites W1990267923 @default.
- W4200559809 cites W1992049020 @default.
- W4200559809 cites W1992935314 @default.
- W4200559809 cites W1993571663 @default.
- W4200559809 cites W1994674541 @default.
- W4200559809 cites W1995856499 @default.
- W4200559809 cites W1997312624 @default.
- W4200559809 cites W2001273962 @default.
- W4200559809 cites W2001403475 @default.
- W4200559809 cites W2001720505 @default.
- W4200559809 cites W2002648786 @default.
- W4200559809 cites W2003425662 @default.
- W4200559809 cites W2003427109 @default.
- W4200559809 cites W2004349171 @default.
- W4200559809 cites W2006086694 @default.
- W4200559809 cites W2008382643 @default.
- W4200559809 cites W2009129665 @default.
- W4200559809 cites W2009891171 @default.
- W4200559809 cites W2010179451 @default.
- W4200559809 cites W2010230081 @default.
- W4200559809 cites W2010417927 @default.
- W4200559809 cites W2012099961 @default.
- W4200559809 cites W2012699085 @default.
- W4200559809 cites W2015541518 @default.
- W4200559809 cites W2015958589 @default.
- W4200559809 cites W2018365251 @default.
- W4200559809 cites W2020580213 @default.
- W4200559809 cites W2023942118 @default.
- W4200559809 cites W2025338451 @default.
- W4200559809 cites W2026433865 @default.
- W4200559809 cites W2027272551 @default.
- W4200559809 cites W2028169108 @default.
- W4200559809 cites W2028361915 @default.
- W4200559809 cites W2030877933 @default.
- W4200559809 cites W2033236322 @default.
- W4200559809 cites W2034191007 @default.
- W4200559809 cites W2034657763 @default.
- W4200559809 cites W2037655774 @default.
- W4200559809 cites W2038735315 @default.
- W4200559809 cites W2038861500 @default.
- W4200559809 cites W2039846010 @default.
- W4200559809 cites W2040881358 @default.
- W4200559809 cites W2041968141 @default.
- W4200559809 cites W2043122628 @default.
- W4200559809 cites W2046466087 @default.
- W4200559809 cites W2049083004 @default.
- W4200559809 cites W2049212848 @default.
- W4200559809 cites W2051021067 @default.
- W4200559809 cites W2055408207 @default.
- W4200559809 cites W2058209163 @default.
- W4200559809 cites W2058567239 @default.
- W4200559809 cites W2059718338 @default.
- W4200559809 cites W2060261324 @default.
- W4200559809 cites W2060395669 @default.
- W4200559809 cites W2061560102 @default.
- W4200559809 cites W2061765285 @default.
- W4200559809 cites W2064487089 @default.
- W4200559809 cites W2066727707 @default.
- W4200559809 cites W2066786994 @default.
- W4200559809 cites W2068337326 @default.