Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200561657> ?p ?o ?g. }
- W4200561657 endingPage "9" @default.
- W4200561657 startingPage "9" @default.
- W4200561657 abstract "Periodontitis is a multifactorial chronic inflammatory disease that affects tooth-supporting soft/hard tissues of the dentition. The dental plaque biofilm is considered as a primary etiological factor in susceptible patients; however, other factors contribute to progression, such as diabetes and smoking. Current management utilizes mechanical biofilm removal as the gold standard of treatment. Antibacterial agents might be indicated in certain conditions as an adjunct to this mechanical approach. However, in view of the growing concern about bacterial resistance, alternative approaches have been investigated. Currently, a range of antimicrobial agents and protocols have been used in clinical management, but these remain largely non-validated. This review aimed to evaluate the efficacy of adjunctive antibiotic use in periodontal management and to compare them to recently suggested alternatives. Evidence from in vitro, observational and clinical trial studies suggests efficacy in the use of adjunctive antimicrobials in patients with grade C periodontitis of young age or where the associated risk factors are inconsistent with the amount of bone loss present. Meanwhile, alternative approaches such as photodynamic therapy, bacteriophage therapy and probiotics showed limited supportive evidence, and more studies are warranted to validate their efficiency." @default.
- W4200561657 created "2021-12-31" @default.
- W4200561657 creator A5002969674 @default.
- W4200561657 creator A5013353745 @default.
- W4200561657 creator A5016483338 @default.
- W4200561657 creator A5022481506 @default.
- W4200561657 creator A5034288325 @default.
- W4200561657 creator A5091408144 @default.
- W4200561657 date "2021-12-22" @default.
- W4200561657 modified "2023-10-14" @default.
- W4200561657 title "Classic vs. Novel Antibacterial Approaches for Eradicating Dental Biofilm as Adjunct to Periodontal Debridement: An Evidence-Based Overview" @default.
- W4200561657 cites W125939506 @default.
- W4200561657 cites W1495582815 @default.
- W4200561657 cites W1948857334 @default.
- W4200561657 cites W1965799929 @default.
- W4200561657 cites W1968149571 @default.
- W4200561657 cites W1968340922 @default.
- W4200561657 cites W1970179763 @default.
- W4200561657 cites W1970397496 @default.
- W4200561657 cites W1973435715 @default.
- W4200561657 cites W1980595924 @default.
- W4200561657 cites W1981781283 @default.
- W4200561657 cites W1985779476 @default.
- W4200561657 cites W1994482779 @default.
- W4200561657 cites W1994499151 @default.
- W4200561657 cites W2002086667 @default.
- W4200561657 cites W2008620315 @default.
- W4200561657 cites W2016267328 @default.
- W4200561657 cites W2018546603 @default.
- W4200561657 cites W2019544722 @default.
- W4200561657 cites W2022813005 @default.
- W4200561657 cites W2025370768 @default.
- W4200561657 cites W2031105985 @default.
- W4200561657 cites W2036760952 @default.
- W4200561657 cites W2039631247 @default.
- W4200561657 cites W2040154973 @default.
- W4200561657 cites W2041395965 @default.
- W4200561657 cites W2045812506 @default.
- W4200561657 cites W2047181164 @default.
- W4200561657 cites W2049899624 @default.
- W4200561657 cites W2063051937 @default.
- W4200561657 cites W2064490771 @default.
- W4200561657 cites W2065536131 @default.
- W4200561657 cites W2066595318 @default.
- W4200561657 cites W2070115603 @default.
- W4200561657 cites W2072529591 @default.
- W4200561657 cites W2079399872 @default.
- W4200561657 cites W2079692416 @default.
- W4200561657 cites W2079883332 @default.
- W4200561657 cites W2080223747 @default.
- W4200561657 cites W2089453517 @default.
- W4200561657 cites W2094894598 @default.
- W4200561657 cites W2095011303 @default.
- W4200561657 cites W2096052895 @default.
- W4200561657 cites W2096279874 @default.
- W4200561657 cites W2098438203 @default.
- W4200561657 cites W2099652820 @default.
- W4200561657 cites W2101548120 @default.
- W4200561657 cites W2104094339 @default.
- W4200561657 cites W2106351298 @default.
- W4200561657 cites W2116475591 @default.
- W4200561657 cites W2119596678 @default.
- W4200561657 cites W2119629693 @default.
- W4200561657 cites W2121636869 @default.
- W4200561657 cites W2121671563 @default.
- W4200561657 cites W2121748291 @default.
- W4200561657 cites W2123686512 @default.
- W4200561657 cites W2126922170 @default.
- W4200561657 cites W2129265198 @default.
- W4200561657 cites W2131296994 @default.
- W4200561657 cites W2133877274 @default.
- W4200561657 cites W2133971477 @default.
- W4200561657 cites W2139318392 @default.
- W4200561657 cites W2141474275 @default.
- W4200561657 cites W2143261190 @default.
- W4200561657 cites W2149898918 @default.
- W4200561657 cites W2150900523 @default.
- W4200561657 cites W2158125149 @default.
- W4200561657 cites W2164006773 @default.
- W4200561657 cites W2166739522 @default.
- W4200561657 cites W2167402870 @default.
- W4200561657 cites W2168519960 @default.
- W4200561657 cites W2169103138 @default.
- W4200561657 cites W2171574454 @default.
- W4200561657 cites W2173093977 @default.
- W4200561657 cites W2334701886 @default.
- W4200561657 cites W2419504090 @default.
- W4200561657 cites W2544044951 @default.
- W4200561657 cites W2559411880 @default.
- W4200561657 cites W2566411326 @default.
- W4200561657 cites W2587462805 @default.
- W4200561657 cites W2600121819 @default.
- W4200561657 cites W2604539372 @default.
- W4200561657 cites W2625963313 @default.
- W4200561657 cites W2727949562 @default.
- W4200561657 cites W2730741903 @default.
- W4200561657 cites W2739967550 @default.
- W4200561657 cites W2740420335 @default.