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• W4200563404 endingPage "152291" @default.
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• W4200563404 abstract "Sensory over-responsivity (SOR) refers to excessively intense and/or prolonged behavioral responses to environmental stimuli typically perceived as non-aversive. SOR is prevalent in several neurodevelopmental disorders, including chronic tic disorders (CTDs) and obsessive-compulsive disorder (OCD). Few studies have examined the extent and clinical correlates of SOR across disorders, limiting insights into the phenomenon's transdiagnostic clinical and biological relevance. Such cross-disorder comparisons are of particular interest for CTDs and OCD given their frequent co-occurrence. We sought to compare the magnitude of SOR between adults with CTD and adults with OCD and to identify the clinical factors most strongly associated with SOR across these disorders. We enrolled 207 age- and sex-matched participants across four diagnostic categories: CTD without OCD (designated “CTD/OCD-”; n = 37), CTD with OCD (“CTD/OCD+”; n = 32), OCD without tic disorder (“OCD”; n = 69), and healthy controls (n = 69). Participants completed a self-report battery of rating scales assessing SOR (Sensory Gating Inventory, SGI), obsessive-compulsive symptoms (Dimensional Obsessive-Compulsive Scale, DOCS), inattention and hyperactivity (Adult ADHD Self-Report Screening Scale for DSM-5, ASRS-5), anxiety (Generalized Anxiety Disorder-7), and depression (Patient Health Questionnaire-9). CTD participants were also administered the Yale Global Tic Severity Scale (YGTSS). To examine between-group differences in SOR, we compared SGI score across all groups and between pairs of groups. To examine the relationship of SOR with other clinical factors, we performed multivariable linear regression. CTD/OCD-, CTD/OCD+, and OCD participants were 86.7%, 87.6%, and 89.5%, respectively, more likely to have higher SGI total scores than healthy controls. SGI total score did not differ between CTD/OCD-, CTD/OCD+, and OCD groups. In the regression model of log-transformed SGI total score, OCD diagnosis, DOCS score, and ASRS-5 score each contributed significantly to model goodness-of-fit, whereas CTD diagnosis and YGTSS total tic score did not. SOR is prevalent in adults with CTD and in adults with OCD but does not significantly differ in magnitude between these disorders. Across CTD, OCD, and healthy control adult populations, SOR is independently associated with both obsessive-compulsive and ADHD symptoms, suggesting a transdiagnostic relationship between these sensory and psychiatric manifestations. Future cross-disorder, longitudinal, and translational research is needed to clarify the role and prognostic import of SOR in CTDs, OCD, and other neurodevelopmental disorders." @default.
• W4200563404 created "2021-12-31" @default.
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• W4200563404 date "2022-02-01" @default.
• W4200563404 modified "2023-10-14" @default.
• W4200563404 title "Cross-disorder comparison of sensory over-responsivity in chronic tic disorders and obsessive-compulsive disorder" @default.
• W4200563404 cites W1523220139 @default.
• W4200563404 cites W1769700044 @default.
• W4200563404 cites W1870699277 @default.
• W4200563404 cites W1897540775 @default.
• W4200563404 cites W1903774788 @default.
• W4200563404 cites W1967962717 @default.
• W4200563404 cites W1970091823 @default.
• W4200563404 cites W1977465442 @default.
• W4200563404 cites W1979617279 @default.
• W4200563404 cites W1979944402 @default.
• W4200563404 cites W1984200400 @default.
• W4200563404 cites W1986747470 @default.
• W4200563404 cites W1988022951 @default.
• W4200563404 cites W1989813452 @default.
• W4200563404 cites W1991526533 @default.
• W4200563404 cites W1995375461 @default.
• W4200563404 cites W1995571427 @default.
• W4200563404 cites W1996586144 @default.
• W4200563404 cites W1999962303 @default.
• W4200563404 cites W2001633786 @default.
• W4200563404 cites W2007486119 @default.
• W4200563404 cites W2010651179 @default.
• W4200563404 cites W2011307457 @default.
• W4200563404 cites W2018157180 @default.
• W4200563404 cites W2019101336 @default.
• W4200563404 cites W2024182137 @default.
• W4200563404 cites W2033442056 @default.
• W4200563404 cites W2039655209 @default.
• W4200563404 cites W2040477268 @default.
• W4200563404 cites W2042326664 @default.
• W4200563404 cites W2043705607 @default.
• W4200563404 cites W2045861558 @default.
• W4200563404 cites W2046792752 @default.
• W4200563404 cites W2048405858 @default.
• W4200563404 cites W2049398634 @default.
• W4200563404 cites W2051190092 @default.
• W4200563404 cites W2051540231 @default.
• W4200563404 cites W2053418196 @default.
• W4200563404 cites W2053922060 @default.
• W4200563404 cites W2054260463 @default.
• W4200563404 cites W2054471938 @default.
• W4200563404 cites W2056469339 @default.
• W4200563404 cites W2058393559 @default.
• W4200563404 cites W2059476663 @default.
• W4200563404 cites W2069967943 @default.
• W4200563404 cites W2078668867 @default.
• W4200563404 cites W2085741294 @default.
• W4200563404 cites W2089804295 @default.
• W4200563404 cites W2090905688 @default.
• W4200563404 cites W2093274439 @default.
• W4200563404 cites W2096065423 @default.
• W4200563404 cites W2106068319 @default.
• W4200563404 cites W2107555020 @default.
• W4200563404 cites W2108710427 @default.
• W4200563404 cites W2118328164 @default.
• W4200563404 cites W2119126350 @default.
• W4200563404 cites W2132322340 @default.
• W4200563404 cites W2137129675 @default.
• W4200563404 cites W2139847983 @default.
• W4200563404 cites W2144592891 @default.
• W4200563404 cites W2146283620 @default.
• W4200563404 cites W2147797459 @default.
• W4200563404 cites W2153654111 @default.
• W4200563404 cites W2158314844 @default.
• W4200563404 cites W2167106420 @default.
• W4200563404 cites W2169609489 @default.
• W4200563404 cites W2183447823 @default.
• W4200563404 cites W2213175826 @default.
• W4200563404 cites W2237402247 @default.
• W4200563404 cites W2250262852 @default.
• W4200563404 cites W2274382726 @default.
• W4200563404 cites W2280520533 @default.
• W4200563404 cites W2288066763 @default.
• W4200563404 cites W2322562838 @default.
• W4200563404 cites W2338184685 @default.
• W4200563404 cites W2338593949 @default.
• W4200563404 cites W2415859261 @default.
• W4200563404 cites W2428358607 @default.
• W4200563404 cites W2554090897 @default.
• W4200563404 cites W2582737854 @default.
• W4200563404 cites W2586047144 @default.
• W4200563404 cites W2591089055 @default.
• W4200563404 cites W2604231045 @default.
• W4200563404 cites W2605277942 @default.
• W4200563404 cites W2765150568 @default.

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