Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200565327> ?p ?o ?g. }
- W4200565327 endingPage "26395" @default.
- W4200565327 startingPage "26388" @default.
- W4200565327 abstract "Abstract A new reaction mode of palladium/norbornene (Pd/NBE) cooperative catalysis is reported involving the selective coupling of two different carbon‐based electrophiles for vicinal double C‐H functionalization of five‐membered heteroarenes in a site‐selective and redox‐neutral manner. The key is to use alkynyl bromides as the second electrophile, which allows vicinal difunctionalization of a wide range of heteroarenes including pyrroles, thiophenes and furans at their C4 and C5 positions. One‐ or two‐step tetrafunctionalizations of simple pyrrole and thiophene have also been realized. The C2‐substituted NBEs prove most effective in these reactions, and the mechanistic exploration discloses the origin of the high selectivity of this transformation. Synthetic utility of this method has been exemplified in the concise preparations of thiophene‐containing organic materials and a protein kinase inhibitor analogue. Preliminary success has also been achieved in a direct annulation event, using a tethered ketone as the second electrophile." @default.
- W4200565327 created "2021-12-31" @default.
- W4200565327 creator A5023312754 @default.
- W4200565327 creator A5034185896 @default.
- W4200565327 date "2021-11-10" @default.
- W4200565327 modified "2023-09-26" @default.
- W4200565327 title "Redox‐Neutral Vicinal Difunctionalization of Five‐Membered Heteroarenes with Dual Electrophiles" @default.
- W4200565327 cites W1561994016 @default.
- W4200565327 cites W1900550888 @default.
- W4200565327 cites W1974001124 @default.
- W4200565327 cites W1977120818 @default.
- W4200565327 cites W1997836065 @default.
- W4200565327 cites W2007344962 @default.
- W4200565327 cites W2017526840 @default.
- W4200565327 cites W2021021033 @default.
- W4200565327 cites W2021428410 @default.
- W4200565327 cites W2025004555 @default.
- W4200565327 cites W2042415587 @default.
- W4200565327 cites W2045718125 @default.
- W4200565327 cites W2050408187 @default.
- W4200565327 cites W2056067304 @default.
- W4200565327 cites W2057052945 @default.
- W4200565327 cites W2066309940 @default.
- W4200565327 cites W2072356342 @default.
- W4200565327 cites W2078403880 @default.
- W4200565327 cites W2121780766 @default.
- W4200565327 cites W2133275647 @default.
- W4200565327 cites W2140187528 @default.
- W4200565327 cites W2146928339 @default.
- W4200565327 cites W2147744585 @default.
- W4200565327 cites W2156521616 @default.
- W4200565327 cites W2161243905 @default.
- W4200565327 cites W2166918689 @default.
- W4200565327 cites W2310460235 @default.
- W4200565327 cites W2330402550 @default.
- W4200565327 cites W2332846669 @default.
- W4200565327 cites W2413721036 @default.
- W4200565327 cites W2465616692 @default.
- W4200565327 cites W2470659897 @default.
- W4200565327 cites W2601109746 @default.
- W4200565327 cites W2603278492 @default.
- W4200565327 cites W2626861271 @default.
- W4200565327 cites W2763153500 @default.
- W4200565327 cites W2768289151 @default.
- W4200565327 cites W2776659797 @default.
- W4200565327 cites W2786290201 @default.
- W4200565327 cites W2796725706 @default.
- W4200565327 cites W2800117630 @default.
- W4200565327 cites W2808817087 @default.
- W4200565327 cites W2810123606 @default.
- W4200565327 cites W2884302869 @default.
- W4200565327 cites W2894305660 @default.
- W4200565327 cites W2895566609 @default.
- W4200565327 cites W2898744666 @default.
- W4200565327 cites W2907559794 @default.
- W4200565327 cites W2919334956 @default.
- W4200565327 cites W2941778284 @default.
- W4200565327 cites W2963566360 @default.
- W4200565327 cites W2964199421 @default.
- W4200565327 cites W2966568798 @default.
- W4200565327 cites W2984639643 @default.
- W4200565327 cites W2990946610 @default.
- W4200565327 cites W2999290238 @default.
- W4200565327 cites W3001310858 @default.
- W4200565327 cites W3014618695 @default.
- W4200565327 cites W3017633759 @default.
- W4200565327 cites W3041497967 @default.
- W4200565327 cites W3048453564 @default.
- W4200565327 cites W3091718007 @default.
- W4200565327 cites W3179030291 @default.
- W4200565327 cites W4205891150 @default.
- W4200565327 cites W4210982029 @default.
- W4200565327 cites W4236391966 @default.
- W4200565327 cites W4237922335 @default.
- W4200565327 cites W4241472398 @default.
- W4200565327 cites W4242918878 @default.
- W4200565327 cites W4252446087 @default.
- W4200565327 doi "https://doi.org/10.1002/ange.202110971" @default.
- W4200565327 hasPublicationYear "2021" @default.
- W4200565327 type Work @default.
- W4200565327 citedByCount "2" @default.
- W4200565327 countsByYear W42005653272022 @default.
- W4200565327 crossrefType "journal-article" @default.
- W4200565327 hasAuthorship W4200565327A5023312754 @default.
- W4200565327 hasAuthorship W4200565327A5034185896 @default.
- W4200565327 hasConcept C118792377 @default.
- W4200565327 hasConcept C121349320 @default.
- W4200565327 hasConcept C161790260 @default.
- W4200565327 hasConcept C166940927 @default.
- W4200565327 hasConcept C178790620 @default.
- W4200565327 hasConcept C185592680 @default.
- W4200565327 hasConcept C21951064 @default.
- W4200565327 hasConcept C2777738585 @default.
- W4200565327 hasConcept C2779400197 @default.
- W4200565327 hasConcept C2779953032 @default.
- W4200565327 hasConcept C2780547246 @default.
- W4200565327 hasConcept C50027330 @default.
- W4200565327 hasConcept C521977710 @default.