FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200569662> ?p ?o ?g. }

• W4200569662 abstract "Abstract Social isolation has been suggested to increase the risk to develop cognitive decline. However, our knowledge on causality and neurobiological underpinnings is still limited. In this preregistered analysis, we tested the impact of social isolation on central features of brain and cognitive aging using a longitudinal population-based magnetic resonance imaging (MRI) study. Assaying 1335 cognitively healthy participants (50-80 years old, 659 women) at baseline and 895 participants after ∼6 years follow-up, we found baseline social isolation and change in social isolation to be associated with smaller volumes of the hippocampus, reduced cortical thickness and poorer cognitive functions. Combining advanced neuroimaging outcomes with prevalent lifestyle characteristics from a well-characterized population of middle- to older aged adults, we provide evidence that social isolation contributes to human brain atrophy and cognitive decline. Within-subject effects of social isolation were similar to between-subject effects, indicating an opportunity to reduce dementia risk by promoting social networks." @default.
• W4200569662 created "2021-12-31" @default.
• W4200569662 creator A5002869107 @default.
• W4200569662 creator A5010965658 @default.
• W4200569662 creator A5020270555 @default.
• W4200569662 creator A5025964385 @default.
• W4200569662 creator A5027776523 @default.
• W4200569662 creator A5028426288 @default.
• W4200569662 creator A5031005510 @default.
• W4200569662 creator A5033292535 @default.
• W4200569662 creator A5059855065 @default.
• W4200569662 creator A5066801947 @default.
• W4200569662 creator A5082637425 @default.
• W4200569662 date "2021-12-16" @default.
• W4200569662 modified "2023-10-16" @default.
• W4200569662 title "Social isolation is linked to declining grey matter structure and cognitive functions in the LIFE-Adult panel study" @default.
• W4200569662 cites W1749244360 @default.
• W4200569662 cites W1820863330 @default.
• W4200569662 cites W1919216659 @default.
• W4200569662 cites W1967202791 @default.
• W4200569662 cites W1981457167 @default.
• W4200569662 cites W1993571512 @default.
• W4200569662 cites W1999574550 @default.
• W4200569662 cites W2000617794 @default.
• W4200569662 cites W2004772296 @default.
• W4200569662 cites W2012133068 @default.
• W4200569662 cites W2015227273 @default.
• W4200569662 cites W2023803373 @default.
• W4200569662 cites W2042221209 @default.
• W4200569662 cites W2042865986 @default.
• W4200569662 cites W2072843066 @default.
• W4200569662 cites W2081861598 @default.
• W4200569662 cites W2084085196 @default.
• W4200569662 cites W2085037176 @default.
• W4200569662 cites W2095448457 @default.
• W4200569662 cites W2105090664 @default.
• W4200569662 cites W2105381419 @default.
• W4200569662 cites W2112778345 @default.
• W4200569662 cites W2113085067 @default.
• W4200569662 cites W2116281003 @default.
• W4200569662 cites W2128127086 @default.
• W4200569662 cites W2132114367 @default.
• W4200569662 cites W2133703021 @default.
• W4200569662 cites W2139886607 @default.
• W4200569662 cites W2142864721 @default.
• W4200569662 cites W2155988679 @default.
• W4200569662 cites W2156362071 @default.
• W4200569662 cites W2159019462 @default.
• W4200569662 cites W2162896254 @default.
• W4200569662 cites W2263173985 @default.
• W4200569662 cites W2278034893 @default.
• W4200569662 cites W2312464103 @default.
• W4200569662 cites W2322155286 @default.
• W4200569662 cites W2327332664 @default.
• W4200569662 cites W2337665433 @default.
• W4200569662 cites W2341545815 @default.
• W4200569662 cites W2419641359 @default.
• W4200569662 cites W2606872799 @default.
• W4200569662 cites W2774486220 @default.
• W4200569662 cites W2779812635 @default.
• W4200569662 cites W2787666045 @default.
• W4200569662 cites W2801801043 @default.
• W4200569662 cites W2893904267 @default.
• W4200569662 cites W2896003083 @default.
• W4200569662 cites W2898523231 @default.
• W4200569662 cites W2898978953 @default.
• W4200569662 cites W2911135784 @default.
• W4200569662 cites W2919786092 @default.
• W4200569662 cites W2937543516 @default.
• W4200569662 cites W2942662932 @default.
• W4200569662 cites W2945690835 @default.
• W4200569662 cites W2977685912 @default.
• W4200569662 cites W2985923507 @default.
• W4200569662 cites W2990762867 @default.
• W4200569662 cites W3005752402 @default.
• W4200569662 cites W3008215350 @default.
• W4200569662 cites W3033043465 @default.
• W4200569662 cites W3037007306 @default.
• W4200569662 cites W3046275966 @default.
• W4200569662 cites W3092849554 @default.
• W4200569662 cites W3097527510 @default.
• W4200569662 cites W3111446413 @default.
• W4200569662 cites W3134120952 @default.
• W4200569662 cites W3157448257 @default.
• W4200569662 cites W3163915883 @default.
• W4200569662 cites W3188599700 @default.
• W4200569662 cites W3197837485 @default.
• W4200569662 cites W3199357992 @default.
• W4200569662 cites W4200569662 @default.
• W4200569662 cites W4244323414 @default.
• W4200569662 cites W4251497824 @default.
• W4200569662 cites W4252015615 @default.
• W4200569662 cites W4252655171 @default.
• W4200569662 cites W4254057566 @default.
• W4200569662 cites W4281763070 @default.
• W4200569662 cites W4282943132 @default.
• W4200569662 doi "https://doi.org/10.1101/2021.12.14.21267787" @default.
• W4200569662 hasPublicationYear "2021" @default.
• W4200569662 type Work @default.
• W4200569662 citedByCount "2" @default.

• next